-
1
-
-
0344303666
-
Depentylation of methyl-n-[4,5-3H]amylnitrosamine by rat liver microsomes and by human cytochrome P450 2E1
-
Chen, S. C., Wang, X. J., Vennerstrom, J. L., Gonzalez, F., Korzekwa, K., and Mirvish, S. S. Depentylation of methyl-n-[4,5-3H]amylnitrosamine by rat liver microsomes and by human cytochrome P450 2E1. Proc. Am. Assoc. Cancer Res., 36: 149, 1995.
-
(1995)
Proc. Am. Assoc. Cancer Res.
, vol.36
, pp. 149
-
-
Chen, S.C.1
Wang, X.J.2
Vennerstrom, J.L.3
Gonzalez, F.4
Korzekwa, K.5
Mirvish, S.S.6
-
2
-
-
0345166121
-
Depentylation of methyl-n-amylnitrosamine by rat esophageal microsomes
-
Chen, S. C., Gelboin, H. V., and Mirvish, S. S. Depentylation of methyl-n-amylnitrosamine by rat esophageal microsomes. Proc. Am. Assoc. Cancer Res., 38: 339, 1997.
-
(1997)
Proc. Am. Assoc. Cancer Res.
, vol.38
, pp. 339
-
-
Chen, S.C.1
Gelboin, H.V.2
Mirvish, S.S.3
-
3
-
-
0018717884
-
Carcinogenesis in rat esophagus by intraperitoneal injection of different doses of methyl-n-amylnitrosamine
-
Bulay, O., and Mirvish, S. S. Carcinogenesis in rat esophagus by intraperitoneal injection of different doses of methyl-n-amylnitrosamine. Cancer Res., 39: 3644-3648, 1979.
-
(1979)
Cancer Res.
, vol.39
, pp. 3644-3648
-
-
Bulay, O.1
Mirvish, S.S.2
-
4
-
-
0029071838
-
Role of N-nitroso compounds (NOC) in etiology of gastric, esophageal, nasopharyngeal and bladder cancer, and contribution to cancer of known exposures to NOC
-
Mirvish, S. S. Role of N-nitroso compounds (NOC) in etiology of gastric, esophageal, nasopharyngeal and bladder cancer, and contribution to cancer of known exposures to NOC. Cancer Lett., 93: 17-48, 1995.
-
(1995)
Cancer Lett.
, vol.93
, pp. 17-48
-
-
Mirvish, S.S.1
-
5
-
-
0022992114
-
Synthesis of nitrosomethylisoamylamine from isoamylamine and sodium nitrite by fungi
-
Lond.
-
Ji, C., Li, M. H., Li, J. L., and Lu, S. J. Synthesis of nitrosomethylisoamylamine from isoamylamine and sodium nitrite by fungi. Carcinogenesis (Lond.), 7: 301-303, 1986.
-
(1986)
Carcinogenesis
, vol.7
, pp. 301-303
-
-
Ji, C.1
Li, M.H.2
Li, J.L.3
Lu, S.J.4
-
6
-
-
0002624810
-
N-Nitroso carcinogens
-
C. E. Searle (ed.), Washington, DC: American Chemical Society
-
Preussmann, R., and Stewart, B. W. N-Nitroso carcinogens. In. C. E. Searle (ed.), Chemical Carcinogens. ACS Monograph 182, pp. 643-828. Washington, DC: American Chemical Society, 1984.
-
(1984)
Chemical Carcinogens. ACS Monograph
, vol.182
, pp. 643-828
-
-
Preussmann, R.1
Stewart, B.W.2
-
7
-
-
0001760345
-
Isolation and characterization of N-alkyl-N-(hydroxymethyl)nitrosamines from N-alkyl-N-(hydroperoxymethyl)nitrosamines by deoxygenation
-
Mochizuki, M., Anjo, T., and Okada, M. Isolation and characterization of N-alkyl-N-(hydroxymethyl)nitrosamines from N-alkyl-N-(hydroperoxymethyl)nitrosamines by deoxygenation. Tetrahedron Lett., 21: 3693-3696, 1980.
-
(1980)
Tetrahedron Lett.
, vol.21
, pp. 3693-3696
-
-
Mochizuki, M.1
Anjo, T.2
Okada, M.3
-
8
-
-
0344303643
-
Further studies on nitrosamine diffusion through rat esophagus as a factor in esophageal carcinogenesis
-
Haorah, J., Miller, D. W., Brand, R., Wang, X., Chen, S. C. and Mirvish, S. S. Further studies on nitrosamine diffusion through rat esophagus as a factor in esophageal carcinogenesis. Proc. Am. Assoc. Cancer Res. 39: 332, 1998.
-
(1998)
Proc. Am. Assoc. Cancer Res.
, vol.39
, pp. 332
-
-
Haorah, J.1
Miller, D.W.2
Brand, R.3
Wang, X.4
Chen, S.C.5
Mirvish, S.S.6
-
9
-
-
0024455901
-
Formation of hydroxy derivatives, aldehydes and nitrite from N-nitrosomethyl-N-amylamine by rat liver microsomes and by purified cytochrome P-450 IIB1
-
Ji, C., Mirvish, S. S., Nickols, J., Ishizaki, H., Lee, M. J., and Yang, C. S. Formation of hydroxy derivatives, aldehydes and nitrite from N-nitrosomethyl-N-amylamine by rat liver microsomes and by purified cytochrome P-450 IIB1. Cancer Res., 49: 5299-5304, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 5299-5304
-
-
Ji, C.1
Mirvish, S.S.2
Nickols, J.3
Ishizaki, H.4
Lee, M.J.5
Yang, C.S.6
-
10
-
-
0020444622
-
The metabolism of a series of methylakylnitrosamines
-
Lond.
-
Farrelly, J. G., and Stewart, M. L. The metabolism of a series of methylakylnitrosamines. Carcinogenesis (Lond.), 3: 1299-1302, 1982.
-
(1982)
Carcinogenesis
, vol.3
, pp. 1299-1302
-
-
Farrelly, J.G.1
Stewart, M.L.2
-
11
-
-
0025890298
-
Positional specificity for methyl-n-amylnitrosamine hydroxylation by cytochrome P-450 isozymes determined with monoclonal antibodies
-
Mirvish, S. S., Huang, Q., Ji, C. Wang, S., Park, S. S., and Gelboin, H. V. Positional specificity for methyl-n-amylnitrosamine hydroxylation by cytochrome P-450 isozymes determined with monoclonal antibodies. Cancer Res.. 51: 1059-1064, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 1059-1064
-
-
Mirvish, S.S.1
Huang, Q.2
Ji, C.3
Wang, S.4
Park, S.S.5
Gelboin, H.V.6
-
12
-
-
0026638747
-
Metabolism of N-nitrosomethyl-n-amylamine by microsomes from human and rat esophagus
-
Huang, Q., Stoner, G., Resau, J., Nickols, J., and Mirvish, S. S. Metabolism of N-nitrosomethyl-n-amylamine by microsomes from human and rat esophagus. Cancer Res., 52: 3547-3551, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 3547-3551
-
-
Huang, Q.1
Stoner, G.2
Resau, J.3
Nickols, J.4
Mirvish, S.S.5
-
13
-
-
0028557306
-
Evidence for a high-affinity enzyme in rat esophageal microsomes which α-hydroxylates N′-nitrosonornicotine
-
Lond.
-
Murphy, S. E., and Spina, D. A. Evidence for a high-affinity enzyme in rat esophageal microsomes which α-hydroxylates N′-nitrosonornicotine. Carcinogenesis (Lond.), 15: 2709-2713, 1994.
-
(1994)
Carcinogenesis
, vol.15
, pp. 2709-2713
-
-
Murphy, S.E.1
Spina, D.A.2
-
14
-
-
0023790514
-
Organ and cell specificity of DNA methylation by N-nitrosomethylamylamine in rats
-
Koenigsmann, M., Schmerold, I., Jeltsch, W., Ludeke, B., Kleihues, P., and Wiessler, M. Organ and cell specificity of DNA methylation by N-nitrosomethylamylamine in rats. Cancer Res. 48: 5482-5486, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 5482-5486
-
-
Koenigsmann, M.1
Schmerold, I.2
Jeltsch, W.3
Ludeke, B.4
Kleihues, P.5
Wiessler, M.6
-
15
-
-
0027318421
-
Inhibitory effect of phenylethyl and phenylhexyl isothiocyanate on metabolism of and DNA alkylation by N-nitrosomethylamylamine in the rat
-
Lond.
-
Huang, Q., Lawson, T. A., Chung, F. L., and Mirvish, S. S. Inhibitory effect of phenylethyl and phenylhexyl isothiocyanate on metabolism of and DNA alkylation by N-nitrosomethylamylamine in the rat. Carcinogenesis (Lond.), 14: 749-754, 1993.
-
(1993)
Carcinogenesis
, vol.14
, pp. 749-754
-
-
Huang, Q.1
Lawson, T.A.2
Chung, F.L.3
Mirvish, S.S.4
-
16
-
-
0029102767
-
Use of monoclonal antibodies to cytochrome P450s to indicate the critical dealkylation and the P450s involved in methyl-n-amylnitrosamine mutagenicity in the presence of induced rat liver microsomes
-
Mirvish, S. S., Huang, Q., Williamson, J., Chen, S. C., and Gelboin. H. V. Use of monoclonal antibodies to cytochrome P450s to indicate the critical dealkylation and the P450s involved in methyl-n-amylnitrosamine mutagenicity in the presence of induced rat liver microsomes. Mutat. Res., 331: 161-170, 1995.
-
(1995)
Mutat. Res.
, vol.331
, pp. 161-170
-
-
Mirvish, S.S.1
Huang, Q.2
Williamson, J.3
Chen, S.C.4
Gelboin, H.V.5
-
17
-
-
0023924310
-
Cytochrome P450-dependent formation of ethylene from N-nitrosoethylamines
-
Ding, X., and Coon, M. J. Cytochrome P450-dependent formation of ethylene from N-nitrosoethylamines. Drug Metab. Dispos., 16: 265-269, 1988.
-
(1988)
Drug Metab. Dispos.
, vol.16
, pp. 265-269
-
-
Ding, X.1
Coon, M.J.2
-
19
-
-
0026319299
-
Expression of cytochrome P450 cDNAs in human B lymphoblastoid cells: Applications to toxicology and metabolite analysis
-
Crespi, C. L. Expression of cytochrome P450 cDNAs in human B lymphoblastoid cells: applications to toxicology and metabolite analysis. Methods Enzymol., 206: 123-129, 1991.
-
(1991)
Methods Enzymol.
, vol.206
, pp. 123-129
-
-
Crespi, C.L.1
-
20
-
-
0026689048
-
Duodenoesophageal reflux and the development of esophageal adenocarcinoma in rats
-
Attwood, S. E. A., Smyrk, T. C., DeMeester, T. R., Mirvish, S. S., Stein, H. J., and Hinder, R. A. Duodenoesophageal reflux and the development of esophageal adenocarcinoma in rats. Surgery. 111: 503-510, 1992.
-
(1992)
Surgery
, vol.111
, pp. 503-510
-
-
Attwood, S.E.A.1
Smyrk, T.C.2
DeMeester, T.R.3
Mirvish, S.S.4
Stein, H.J.5
Hinder, R.A.6
-
21
-
-
0027759647
-
Cytochrome P450 and monoclonal antibodies
-
Gelboin, H. V. Cytochrome P450 and monoclonal antibodies. Pharmacol Rev., 45: 413-453, 1993.
-
(1993)
Pharmacol Rev.
, vol.45
, pp. 413-453
-
-
Gelboin, H.V.1
-
22
-
-
0021958424
-
Beta to omega hydroxylation of the esophageal carcinogen methyl-n-amylnitrosamine by the rat esophagus and other tissues
-
Mirvish, S. S., Wang, M. Y., Smith, J. W., Deshpande, A. D., Makary, M., and Issenberg, P. Beta to omega hydroxylation of the esophageal carcinogen methyl-n-amylnitrosamine by the rat esophagus and other tissues. Cancer Res., 45: 577-583, 1985
-
(1985)
Cancer Res.
, vol.45
, pp. 577-583
-
-
Mirvish, S.S.1
Wang, M.Y.2
Smith, J.W.3
Deshpande, A.D.4
Makary, M.5
Issenberg, P.6
-
23
-
-
0023680132
-
Hydroxy metabolites of methyl-n-amylnitrosamine produced by esophagus, stomach, liver and other tissues of the neonatal to adult rat and hamster
-
Mirvish, S. S., Ji, C., and Rosinsky, S. Hydroxy metabolites of methyl-n-amylnitrosamine produced by esophagus, stomach, liver and other tissues of the neonatal to adult rat and hamster. Cancer Res., 48: 5663-5668, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 5663-5668
-
-
Mirvish, S.S.1
Ji, C.2
Rosinsky, S.3
-
24
-
-
0031149716
-
Inhibition of coumarin 7-hydroxylase activity in human liver microsomes
-
Draper, A. J., Madan, A., and Parkinson, A. Inhibition of coumarin 7-hydroxylase activity in human liver microsomes. Arch. Biochem. Biophys., 341: 47-61, 1997.
-
(1997)
Arch. Biochem. Biophys.
, vol.341
, pp. 47-61
-
-
Draper, A.J.1
Madan, A.2
Parkinson, A.3
-
25
-
-
0021842439
-
Catalytic and immunological comparison of coumarin 7-hydoxylation in different species
-
Kaipainen, P., Koivusaari, U., and Lang, M. Catalytic and immunological comparison of coumarin 7-hydoxylation in different species. Comp. Biochem. Physiol., 81C: 293-296, 1985.
-
(1985)
Comp. Biochem. Physiol.
, vol.81 C
, pp. 293-296
-
-
Kaipainen, P.1
Koivusaari, U.2
Lang, M.3
-
26
-
-
0021795267
-
Characterization of a major form of rat hepatic microsomal cytochrome P-450 induced by isoniazid
-
Ryan, D. E., Ramanathan, L., Idia, S., Thomas, P. E., Haniu, M., Shively, J. E., Lieber, C. S., and Levin, W. Characterization of a major form of rat hepatic microsomal cytochrome P-450 induced by isoniazid. J. Biol. Chem. 260:6385-6391, 1985.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 6385-6391
-
-
Ryan, D.E.1
Ramanathan, L.2
Idia, S.3
Thomas, P.E.4
Haniu, M.5
Shively, J.E.6
Lieber, C.S.7
Levin, W.8
-
27
-
-
0000689283
-
Immunoblotting and immunodetection
-
J. Janssen (ed.). New York: J. Wiley and Sons
-
Gallagher, S., Winston, S. E., Fuller, S. A., and Hurrell, J. G. R. Immunoblotting and immunodetection. In: J. Janssen (ed.). Current Protocols in Molecular Biology, pp. 10.8.1-10.8.17. New York: J. Wiley and Sons, 1993.
-
(1993)
Current Protocols in Molecular Biology
, pp. 1081-10817
-
-
Gallagher, S.1
Winston, S.E.2
Fuller, S.A.3
Hurrell, J.G.R.4
-
28
-
-
0023263168
-
Nature of N-nitrosodimethylamine demethylase and its inhibitors
-
Yoo, J. S. H., Cheung, R. J., Patten, C. J., Wade, D., and Yang, C. S. Nature of N-nitrosodimethylamine demethylase and its inhibitors. Cancer Res., 47: 3378-3383, 1987.
-
(1987)
Cancer Res.
, vol.47
, pp. 3378-3383
-
-
Yoo, J.S.H.1
Cheung, R.J.2
Patten, C.J.3
Wade, D.4
Yang, C.S.5
-
29
-
-
0027178457
-
Hydroxylation and dealkylation of methyl-n-bulylnitrosamine and role of certain cytochrome P450 isozymes in these reactions
-
Huang, Q., Wang, S., Chen, S. C., Babcook, D. M., Park, S. S., Gelboin, H. V., and Mirvish, S. S. Hydroxylation and dealkylation of methyl-n-bulylnitrosamine and role of certain cytochrome P450 isozymes in these reactions. Cancer Lett., 69: 107-116, 1993.
-
(1993)
Cancer Lett.
, vol.69
, pp. 107-116
-
-
Huang, Q.1
Wang, S.2
Chen, S.C.3
Babcook, D.M.4
Park, S.S.5
Gelboin, H.V.6
Mirvish, S.S.7
-
30
-
-
0345111361
-
Biochemical studies on induction, inhibition, and activation
-
H. P. A. Illing (ed.), Boca Raton, FL: CRC Press, Inc.
-
Benford, D. J., and Bridges, J. W. Biochemical studies on induction, inhibition, and activation. In: H. P. A. Illing (ed.), Xenobiotic Metabolism and Disposition: The Design of Studies on Novel Compounds, pp. 194-207. Boca Raton, FL: CRC Press, Inc., 1998.
-
(1998)
Xenobiotic Metabolism and Disposition: The Design of Studies on Novel Compounds
, pp. 194-207
-
-
Benford, D.J.1
Bridges, J.W.2
-
31
-
-
0004262303
-
-
New York: Academic Press
-
Dixon, M., Webb, M. C., Thorne, C. J. R., and Tiplon, K. F. Enzymes. 3rd ed., pp. 341-353. New York: Academic Press, 1979.
-
(1979)
Enzymes. 3rd Ed.
, pp. 341-353
-
-
Dixon, M.1
Webb, M.C.2
Thorne, C.J.R.3
Tiplon, K.F.4
-
32
-
-
0029877531
-
The effects of dietary ellagic acid on rat hepatic and esophageal mucosal cytochromes P450 and phase II enzymes
-
Lond.
-
Ahn, D., Putt, D., Kresty, L., Stoner, G. D., Fromm, D., and Hollenberg, P. F. The effects of dietary ellagic acid on rat hepatic and esophageal mucosal cytochromes P450 and phase II enzymes. Carcinogenesis (Lond.), 17: 821-828, 1996.
-
(1996)
Carcinogenesis
, vol.17
, pp. 821-828
-
-
Ahn, D.1
Putt, D.2
Kresty, L.3
Stoner, G.D.4
Fromm, D.5
Hollenberg, P.F.6
-
33
-
-
0018414638
-
Comparison of the in vitro mutagenicity and metabolism of dimethylnitrosamine and benzo[a]pyrene in tissues from inbred mice treated with phenobarbital, 3-methylcholanthrene or polychlorinated biphenyls
-
Hutton, J. J., Meier, J., and Hackney, C. Comparison of the in vitro mutagenicity and metabolism of dimethylnitrosamine and benzo[a]pyrene in tissues from inbred mice treated with phenobarbital, 3-methylcholanthrene or polychlorinated biphenyls. Mutat. Res., 66: 75-94, 1979.
-
(1979)
Mutat. Res.
, vol.66
, pp. 75-94
-
-
Hutton, J.J.1
Meier, J.2
Hackney, C.3
-
34
-
-
0025139064
-
Hepatic microsomal oxygenation of aldehydes to carboxylic acids
-
Watanabe, K., Narimatsu, S., Yamamoto, I., and Yoshimura, H. Hepatic microsomal oxygenation of aldehydes to carboxylic acids. Biochem. Biophys. Res. Commun., 166: 1308-1312, 1990.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.166
, pp. 1308-1312
-
-
Watanabe, K.1
Narimatsu, S.2
Yamamoto, I.3
Yoshimura, H.4
-
35
-
-
0345111360
-
α-Hydroxylation of N-nitrosobenzylmethylamine (NBZMA) by rat esophageal microsomes and cytochrome P450 2A3
-
Washington, DC: American Chemical Society
-
Murphy, S. E., Von Weymarn, L. B., Felicia, N. D., and Ding, X. α-Hydroxylation of N-nitrosobenzylmethylamine (NBZMA) by rat esophageal microsomes and cytochrome P450 2A3. In: Abstracts Division Chemical Toxicology. 216th Am. Chem. Soc. Natl. Meet., p. 1. Washington, DC: American Chemical Society, 1998.
-
(1998)
Abstracts Division Chemical Toxicology. 216th Am. Chem. Soc. Natl. Meet.
, pp. 1
-
-
Murphy, S.E.1
Von Weymarn, L.B.2
Felicia, N.D.3
Ding, X.4
-
36
-
-
0024349184
-
Mouse steroid 15a-hydroxylase gene family: Identification of type II P450 as coumarin 7-hydroxylase
-
Negishi, M., Lindberg, R., Burkhart, B., Ichikawa, T., Honkakoskie, P., and Lang, M. Mouse steroid 15a-hydroxylase gene family: identification of type II P450 as coumarin 7-hydroxylase. Biochemistry, 28: 4169-4172, 1989.
-
(1989)
Biochemistry
, vol.28
, pp. 4169-4172
-
-
Negishi, M.1
Lindberg, R.2
Burkhart, B.3
Ichikawa, T.4
Honkakoskie, P.5
Lang, M.6
-
37
-
-
0028810306
-
Cytochrome P450 2A of nasal epithelium: Regulation and role in carcinogen metabolism
-
Bereziat, J. C., Raffalli, F., Schmezer, P., Frei, E., Geneste, O., and Lang, M. A. Cytochrome P450 2A of nasal epithelium: regulation and role in carcinogen metabolism. Mol. Carcinogenesis, 14: 130-139, 1995.
-
(1995)
Mol. Carcinogenesis
, vol.14
, pp. 130-139
-
-
Bereziat, J.C.1
Raffalli, F.2
Schmezer, P.3
Frei, E.4
Geneste, O.5
Lang, M.A.6
-
38
-
-
0025635625
-
Roles of cytochrome P450IIE1 in the dealkylation and denitrosation of N-nitrosodimethylamine and N-nitrosodiethylamine in rat liver microsomes
-
Lond.
-
Yoo, J. S. H., Ishizaki, H., and Yang, C. S. Roles of cytochrome P450IIE1 in the dealkylation and denitrosation of N-nitrosodimethylamine and N-nitrosodiethylamine in rat liver microsomes. Carcinogenesis (Lond.), 11: 2239-2243, 1990.
-
(1990)
Carcinogenesis
, vol.11
, pp. 2239-2243
-
-
Yoo, J.S.H.1
Ishizaki, H.2
Yang, C.S.3
-
39
-
-
0024514295
-
Substrate specificity and alkyl group selectivity in the metabolism of N-nitrosodialkylamines
-
Lee, M., Ishizaki, H., Brady, J. F., and Yang, C. S. Substrate specificity and alkyl group selectivity in the metabolism of N-nitrosodialkylamines. Cancer Res., 49: 1470-1474, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 1470-1474
-
-
Lee, M.1
Ishizaki, H.2
Brady, J.F.3
Yang, C.S.4
-
40
-
-
0029873617
-
Identification of the cytochrome P450 isozymes involved in the metabolism of N-nitrosodipropyl-, N-nitrosodibutyl- and N-nitroso-n-butyl-n-propylamine
-
Lond.
-
Shu, L. M., and Hollenberg, P. F. Identification of the cytochrome P450 isozymes involved in the metabolism of N-nitrosodipropyl-, N-nitrosodibutyl- and N-nitroso-n-butyl-n-propylamine. Carcinogenesis (Lond.), 17: 839-848, 1996.
-
(1996)
Carcinogenesis
, vol.17
, pp. 839-848
-
-
Shu, L.M.1
Hollenberg, P.F.2
-
41
-
-
0026793493
-
Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa
-
Lond.
-
Smith, T. J., Guo, Z., Hong, J-Y., Ning, S. M., Thomas, P. E., and Yang, C. S. Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa. Carcinogenesis (Lond.), 13: 1409-1414, 1992.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1409-1414
-
-
Smith, T.J.1
Guo, Z.2
Hong, J.-Y.3
Ning, S.M.4
Thomas, P.E.5
Yang, C.S.6
-
42
-
-
0025992864
-
Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes
-
Guengerich, F. P., and Shimada, T. Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes. Chem. Res. Toxicol., 4: 391-407, 1991.
-
(1991)
Chem. Res. Toxicol.
, vol.4
, pp. 391-407
-
-
Guengerich, F.P.1
Shimada, T.2
-
43
-
-
0029862553
-
Baculovirus-mediated expression and characterization of rat CYP2A3 and human CYP2A6: Role in metabolic activation of nasal toxicants
-
Liu, C., Zhuo, X. L., Gonzalez, F. J., and Ding, X. X. Baculovirus-mediated expression and characterization of rat CYP2A3 and human CYP2A6: role in metabolic activation of nasal toxicants. Mol. Pharmacol. 50: 781-788, 1996.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 781-788
-
-
Liu, C.1
Zhuo, X.L.2
Gonzalez, F.J.3
Ding, X.X.4
-
44
-
-
0029789370
-
Expression of CYP2A genes in rodent and human nasal mucosa
-
Su, T., Sheng, J. J., Lipinskas, T. W., and Ding, X. Expression of CYP2A genes in rodent and human nasal mucosa. Drug Metab. Dispos., 24: 884-890, 1996.
-
(1996)
Drug Metab. Dispos.
, vol.24
, pp. 884-890
-
-
Su, T.1
Sheng, J.J.2
Lipinskas, T.W.3
Ding, X.4
-
45
-
-
0003973797
-
Depentylation and demethylation of methyl-n-amylnitrosamine by microsomes from human esophagus and other organs
-
Chen, S. C., and Mirvish, S. S. Depentylation and demethylation of methyl-n-amylnitrosamine by microsomes from human esophagus and other organs. Proc. Am. Assoc. Cancer Res., 37: 132, 1996.
-
(1996)
Proc. Am. Assoc. Cancer Res.
, vol.37
, pp. 132
-
-
Chen, S.C.1
Mirvish, S.S.2
-
46
-
-
0028556582
-
Human CYP2A6 activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): Mutational specificity in the gpt gene of AS52 cells
-
Lond.
-
Tiano, H. F., Wang, R-L., Hosokawa, M., Crespi, C., Tindall, K. R., and Langenbach, R. Human CYP2A6 activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): mutational specificity in the gpt gene of AS52 cells. Carcinogenesis (Lond.), 15: 2859-2866, 1994.
-
(1994)
Carcinogenesis
, vol.15
, pp. 2859-2866
-
-
Tiano, H.F.1
Wang, R.-L.2
Hosokawa, M.3
Crespi, C.4
Tindall, K.R.5
Langenbach, R.6
-
47
-
-
0027270458
-
High variability of nitrosamine metabolism among individuals: Role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans
-
Lond.
-
Camus, A. M., Geneste, O., Honkakoskie, P., Bereziat, J. C., Henderson, C. J., Wolf, C. R., Bartsch, H., and Lang, M. A. High variability of nitrosamine metabolism among individuals: role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans. Mol. Carcinogenesis (Lond.), 7: 268-275, 1993.
-
(1993)
Mol. Carcinogenesis
, vol.7
, pp. 268-275
-
-
Camus, A.M.1
Geneste, O.2
Honkakoskie, P.3
Bereziat, J.C.4
Henderson, C.J.5
Wolf, C.R.6
Bartsch, H.7
Lang, M.A.8
-
48
-
-
0026744568
-
Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes
-
Lond.
-
Yamazaki, H., Inui, Y., Yun, C-H., Guengerich, F. P., and Shimada, T. Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes. Carcinogenesis (Lond.), 13: 1789-1794, 1992.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1789-1794
-
-
Yamazaki, H.1
Inui, Y.2
Yun, C.-H.3
Guengerich, F.P.4
Shimada, T.5
-
50
-
-
0344765490
-
Evidence for metabolic activation of N′-nitrosonornicotine and N-nitrosobenzyl methylamine by a rat nasal coumarin hydroxylase
-
Patten, C. J., Peterson, L. A., and Murphy, S. E. Evidence for metabolic activation of N′-nitrosonornicotine and N-nitrosobenzyl methylamine by a rat nasal coumarin hydroxylase. Drug Metab. Dispos., 26: 177-180, 1998.
-
(1998)
Drug Metab. Dispos.
, vol.26
, pp. 177-180
-
-
Patten, C.J.1
Peterson, L.A.2
Murphy, S.E.3
-
51
-
-
0031862390
-
Purification and characterization of heterologously expressed mouse CYP2A5 and CYP2G1: Role in metabolic activation of acetaminophen and 2,6-dichlorobenzonitrile in mouse olfactory mucosal microsomes
-
Gu, J., Zhang, Q. Y., Genter, M. B., Lipinskas, T. W., Negishi, M., Neben, D. W., and Ding, X. X. Purification and characterization of heterologously expressed mouse CYP2A5 and CYP2G1: role in metabolic activation of acetaminophen and 2,6-dichlorobenzonitrile in mouse olfactory mucosal microsomes. J. Pharmacol. Exp. Ther., 285: 1287-1295, 1998.
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.285
, pp. 1287-1295
-
-
Gu, J.1
Zhang, Q.Y.2
Genter, M.B.3
Lipinskas, T.W.4
Negishi, M.5
Neben, D.W.6
Ding, X.X.7
|