Synthesis and dopamine D2-like receptor binding affinity of substituted 5-phenyl-pyrrole-3-carboxamides

Farmaco

Volumn 54, Issue 8, 1999, Pages 542-550

  Pinna, Gérard A ^a   Curzu, Maria M ^a   Sechi, Mario ^a   Chelucci, Giorgio ^a   Maciocco, Elisabetta ^b  

^a UNIVERSITY OF SASSARI   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

D2 like receptor binding; Structure activity relationship; Substituted 5 phenyl pyrrole 3 carboxamides

Indexed keywords

DOPAMINE 2 RECEPTOR; EMONAPRIDE; N [(1 ETHYLTETRAHYDRO 1H 2 PYRROLYL)METHYL] 2 CHLORO 5 PHENYL 1H 3 PYRROLE CARBOXAMIDE; N [(1 ETHYLTETRAHYDRO 1H 2 PYRROLYL)METHYL] 5 PHENYL 1H 3 PYRROLE CARBOXAMIDE; NEUROLEPTIC AGENT; PYRROLE DERIVATIVE; RACLOPRIDE; SULPIRIDE; UNCLASSIFIED DRUG; AMIDE; BENZAMIDE DERIVATIVE; DIAGNOSTIC AGENT; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CAUDATE NUCLEUS; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; RAT; STRUCTURE ACTIVITY RELATION; ANIMAL; BINDING COMPETITION; DRUG EFFECT; MALE; METABOLISM; SPRAGUE DAWLEY RAT; SYNTHESIS;

AMIDES; ANIMALS; BENZAMIDES; BINDING, COMPETITIVE; CAUDATE NUCLEUS; DOPAMINE AGENTS; DOPAMINE ANTAGONISTS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032589349     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(99)00061-0     Document Type: Article

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