Absorption and biodistribution of 111Indium-labelled desferrioxamine (111In-DFO) after subcutaneous injection of 111In-DFO liposomes

Journal of Controlled Release

Volumn 58, Issue 1, 1999, Pages 51-60

  Postma, N S ^a   Boerman, O C ^b   Oyen, W J G ^b   Zuidema, J ^b   Storm, G ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Desferrioxamine; Indium 111 imaging; Liposomes; Subcutaneous administration; Sustained release

Indexed keywords

DEFEROXAMINE; DEFEROXAMINE MESYLATE; INDIUM 111; LIPOSOME; ANTIDOTE; DRUG CARRIER; INDIUM;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DISPERSION; DRUG ABSORPTION; DRUG DISTRIBUTION; ENCAPSULATION; FEMALE; IMAGING; MALARIA; MOUSE; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; SUSTAINED RELEASE FORMULATION; ULTRACENTRIFUGATION; ANIMAL; C57BL MOUSE; INTESTINE ABSORPTION; PARTICLE SIZE; TISSUE DISTRIBUTION;

ANIMALS; ANTIDOTES; DEFEROXAMINE; DRUG CARRIERS; FEMALE; INDIUM RADIOISOTOPES; INJECTIONS, SUBCUTANEOUS; INTESTINAL ABSORPTION; LIPOSOMES; MICE; MICE, INBRED C57BL; PARTICLE SIZE; TISSUE DISTRIBUTION;

EID: 0032588440     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(98)00139-4     Document Type: Article

References (25)

1. Z.I. Cabantchik, H. Glickstein, J. Golenser, M. Loyevsky, A. Tsafack, Iron chelators: mode of action as antimalarials, Acta Haematol. 95 (1996) 70-77.
2. R.L. Van Zyl, I. Havlik, S.E. Monteagudo, The combined effect of iron chelators and classical antimalarials on the in-vitro growth of Plasmodium falciparum, J. Antimicrob. Chemother. 30 (1992) 273-278.
3. V. Gabutti, A. Piga, Results of long-term iron-chelating therapy, Acta Haematol. 95 (1996) 26-36.
4. V. Gordeuk, P. Thuma, G. Brittenham, C. McLaren, D. Parry, A. Backenstose, G. Biemba, R. Msiska, L. Holmes, E. McKinley, L. Vargas, R. Gilkeson, A.A. Poltera, Effect of iron chelating therapy on recovery from deep coma in children with cerebral malaria, New Engl. J. Med. 327 (1992) 1473-1477.
5. G.F. Mabeza, G. Biemba, V.R. Gordeuk, Clinical studies of iron chelators in malaria, Acta Haematol. 95 (1996) 78-86.
6. O. Traore, P. Carnevale, L. Kaptue-Noche, J. M'Bede, M. Desfontaine, J. Elion, D. Labie, R.L. Nagel, Preliminary report on the use of desferrioxamine in the treatment of Plasmodium faliparum malaria, Am. J. Hematol. 37 (1991) 206-208.
7. K.O. Hamilton, L. Stallibras, I. Hassan, Y. Jin, C. Halleux, The transport of two iron chelators, desferrioxamine B and L1, across Caco-2 monolayers, Br. J. Haematol. 86 (1994) 851-857.
8. H. Keberle, The biochemistry of desferrioxamine and its relation to iron metabolism, Ann. New York Acad. Sci. 119 (1964) 758-768.
9. M. Loyevsky, S.D. Lytton, B. Mester, J. Libman, A. Shanzer, Z.I. Cabantchik, The antimalarial action of desferal involves a direct access route to erythrocytic (Plasmodium falciparum) parasites, J. Clin. Invest. 91 (1993) 218-224.
10. M.R. Summers, A. Jacobs, D. Tudway, P. Perera, C. Ricketts, Studies in desferrioxamine and ferrioxamine metabolism in normal and iron-loaded subjects, Br. J. Haematol. 42 (1979) 547-555.
11. F. Kadir, J. Zuidema, D.J.A. Crommelin, in: A. Rolland (Ed.), Pharmaceutical Particulate Carriers in Medical Applications, Marcel Dekker, New York, 1993, pp. 165-198.
12. N.S. Postma, C.C. Hermsen, J. Zuidema, W.M.C. Eling, Plasmodium vinckei: optimisation of desferrioxamine B delivery in the treatment of murine malaria, Exp. Parasitol. in press.
13. O.C. Boerman, G. Storm, W.J.G. Oyen, L. Van Bloois, J.W.M. Van der Meer, R.A.M.J. Claessens, D.J.A. Crommelin, F.H.M. Corstens, Sterically stabilised liposomes labelled with indium-Ill to image focal infection, J. Nucl. Med. 36 (1995) 1639-1644.
14. F.J. Koppenhagen, Thesis, University Utrecht, The Netherlands, 1997.
15. F. Szoka, D. Papahadjopoulos, Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation, Proc. Natl. Acad. Sci. USA 75 (1978) 4194-4198.
16. S. Udenfriend, S. Skin, P. Böhlen, W. Dairman, W. Laingruber, M. Weigele, Fluorescamine: a reagent for assay of amino acids, peptides, proteins and primary amines in the picomole range, Science 178 (1972) 871-872.
17. G. Rouser, S. Fluscher, A. Yamamoto, Two dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots, Lipids 5 (1970) 494-496.
18. I.A.J.M. Bakker-Woudenberg, A.F. Lokerse, M.T. ten Kate, G. Storm, Enhanced localisation of liposomes with prolonged blood circulation time in infected lung tissue, Biochim. Biophys. Acta 1138 (1992) 318-326.
19. C. Oussoren, J. Zuidema, D.J.A. Crommelin, G. Storm, Lymphatic uptake and biodistribution of liposomes after subcutaneous injection. II. Influence of liposomal size, lipid composition and lipid dose, Biochim. Biophys. Acta 1328 (1997) 261-272.
20. C.A. Hunt, V. Liposomes disposition in vivo, Liposome stability and implications for drug carrier functions, Biochim. Biophys. Acta 719 (1982) 450-463.
21. S. Kim, S.B. Howell, Multivesicular liposomes containing cytarabine for slow-release s.c. administration, Cancer Treat. Rep. 71 (1987) 447-450.
22. R. Roy, S. Kim, Multivesicular liposomes containing bleomycin for subcutaneous administration, Cancer Chemother. Pharmacol. 28 (1991) 105-108.
23. R.W. Stevenson, H.M. Patel, J.A. Parsons, B.E. Ryman, Prolonged hypoglymic effect in diabetic dogs due to subcutaneous administration of insulin in liposomes, Diabetes 31 (1982) 506-511.
24. C. Hershko, Iron chelators in medicine, Mol. Asp. Med. 13 (1992) 113-165.
25. R.E. Weiner, M.L. Thakur, M. Goodman, P. Hoffer, Relative stability of In-111 and Ga-67 desferrioxamine and human transferrin complexes, Radiopharmaceuticals II, Society of Nuclear Medicine, New York, 1979, pp. 331-340.