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Life Sciences

Volumn 62, Issue 14, 1998, Pages 1231-1241

Species differences in the disposition of propranolol prodrugs derived from hydrolase activity in intestinal mucosa

(4) Yoshigae, Yasushi a Imai, Teruko a Aso, Tomoyo a Otagiri, Masaki a

a KUMAMOTO UNIVERSITY (Japan)

Author keywords

Brush border membrane vesicle; Intestinal mucosa; Prodrug; Stereoselective hydrolysis

Indexed keywords

HYDROLASE; PRODRUG; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DISPOSITION; DRUG METABOLISM; HUMAN; HUMAN TISSUE; HYDROLYSIS; INTESTINE MUCOSA; LIVER CYTOSOL; LIVER MICROSOME; MALE; NONHUMAN; RAT; SPECIES DIFFERENCE;

ADMINISTRATION, ORAL; ADRENERGIC BETA-ANTAGONISTS; AGED; ANIMALS; BIOLOGICAL AVAILABILITY; CYTOSOL; DOGS; HUMANS; HYDROLASES; HYDROLYSIS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; LIVER; MALE; MICROVILLI; MIDDLE AGED; PRODRUGS; PROPRANOLOL; RATS; RATS, WISTAR; SPECIES SPECIFICITY;

ANIMALIA; CANIS FAMILIARIS;

EID: 0032570881 PISSN: 00243205 EISSN: None Source Type: Journal
DOI: 10.1016/S0024-3205(98)00053-8 Document Type: Article

Times cited : (14)

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