Multiple pathways for regulation of the KCl-induced [3H]-GABA release by metabotropic glutamate receptors, in primary rat cortical cultures

Brain Research

Volumn 782, Issue 1-2, 1998, Pages 91-104

  Schaffhauser, Hervé ^a   Knoflach, Frédéric ^a   Pink, John Richard ^a   Bleuel, Zaiga ^a   Cartmell, Jayne ^a   Goepfert, Fabienne ^a   Kemp, John A ^a   Richards, John Grayson ^a   Adam, Geo ^a   Mutel, Vincent ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

3H GABA; Calcium; Conical culture; Electrophysiology; Metabotropic; Release

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 2 AMINO 4 PHOSPHONOBUTYRIC ACID; 4 AMINOBUTYRIC ACID; CALCIUM CHANNEL; METABOTROPIC RECEPTOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NIFEDIPINE; OMEGA CONOTOXIN; POTASSIUM CHLORIDE;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL CELL; ARTICLE; BRAIN CELL; CELL CULTURE; ELECTROPHYSIOLOGY; EMBRYO; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; RAT; VOLTAGE CLAMP;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CEREBRAL CORTEX; CYCLIC AMP; GAMMA-AMINOBUTYRIC ACID; IN SITU HYBRIDIZATION; PATCH-CLAMP TECHNIQUES; POTASSIUM CHLORIDE; RATS; RATS, INBRED STRAINS; RECEPTORS, METABOTROPIC GLUTAMATE; TRITIUM;

EID: 0032567767     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)01271-7     Document Type: Article

References (49)

1. 2+ signal transduction. J. Biol. Chem. 267:1992;13361-13368.
2. Anson J., Collins G.G.S. Possible presynaptic actions of 2-amino-4-phosphonobutyrate in rat olfactory cortex. Br. J. Pharmacol. 91:1987;753-761.
3. Aramori I., Nakanishi S. Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluR1, in transfected CHO cells. Neuron. 8:1992;757-765.
4. Baskys A., Malenka R.C. Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus. J. Physiol., London. 444:1991;687-701.
5. Brewer G.J., Torricelli J.R., Evege E.K., Price P.J. Optimised survival of hippocampal neurons in B27-supplemented Neurobasal™, a new erum-free medium combination. J. Neurosci. Res. 35:1993;567-576.
6. Chavis P., Shinozaki H., Bockaert J., Fagni L. The metabotropic glutamate receptor types 2/3 inhibit L-type calcium channels via a pertussis toxin-sensitive G-protein in cultured cerebellar granule cells. J. Neurosci. 14:1994;7067-7076.
7. 2+ channels involves multiple receptor subtypes in cortical neurons. J. Neurosci. 16:1996;36-45.
8. Conn P.J., Pin J.P. Pharmacology and functions of metabotropic glutamate receptors. Ann. Rev. Pharmacol. Toxicol. 37:1997;205-237.
9. Duvoisin R.M., Zhang C.X., Ramonell K. A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb. J. Neurosci. 15:1995;3075-3083.
10. Forsythe I.D., Clements J.D. Presynaptic glutamate receptors depress excitatory monosynaptic transmission between mouse hippocampal neurones. J. Physiol. 429:1990;1-16.
11. Fox A.P., Nowycky M.C., Tsien R.W. Kinetic and pharmacological properties distinguishing three types of calcium currents in chick sensory neurones. J. Physiol. 394:1987;149-172.
12. Gomeza J., Mary S., Brabet I., Parmentier M.L., Restituto S., Bockaert J., Pin J.P. Coupling of metabotropic glutamate receptors 2 and 4 to G(alpha 15), G(alpha 16), and chimeric G(alpha q/i) proteins: Characterization of new antagonists. Mol. Pharmacol. 50:1996;923-930.
13. Hamill O.P., Marty A., Neher E., Sakmann B., Sigworth F.J. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflug. Arch. 391:1981;85-100.
14. Hayashi Y., Momiyama A., Takahashi T., Ohishi H., Ogawa-Meguro R., Shigemoto R., Mizuno N., Nakanishi S. Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb. Nature. 366:1993;687-690.
15. 2+](c) but not in cAMP mediates L-AP4 inhibition of glutamate release: PKC-mediated suppression of this inhibitory pathway. Eur. J. Neurosci. 8:1996;700-709.
16. Jane D.E., Thomas N.K., Tse H.W., Watkins J.C. Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord. Neuropharmacology. 35:1996;1029-1035.
17. Johnson J.W., Ascher P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 325:1987;529-531.
18. Kaba H., Hayashi Y., Higuchi T., Nakanishi S. Induction of an olfactory memory by the activation of a metabotropic glutamate receptor. Science. 265:1994;262-264.
19. Kanner B.I., Bendahan A., Radian R. Efflux and exchange of γ-aminogammabutyric acid and nipecotic acid catalysed by synaptic plasma membrane vesicles isolated from immature rat brain. Biochim. Biophys. Acta. 731:1983;54-62.
20. Lanthorn T.H., Ganong A.H., Cotman C.W. 2-Amino-4-phosphonobutyrate selectively blocks mossy fiber-CA3 responses in guinea pig but not in rat hippocampus. Brain Res. 290:1984;174-178.
21. Lombardi G., Pellegrinigiampietro D.E., Leonardi P., Cherici G., Pellicciari R., Moroni F. The depolarization-induced outflow of D-[H-3]aspartate from rat brain slices is modulated by metabotropic glutamate receptors. Neurochem. Int. 24:1994;525-532.
22. Lovinger D.M., Mccool B.A. Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3. J. Neurophysiol. 73:1995;1076-1083.
23. Luque J.M., Malherbe P., Richards J.G. Localization of NMDA receptor subunit mRNAs in the rat locus coeruleus. Brain Res. 29:1995;224-232.
24. McCleskey E.W., Fox A.P., Feldman D.H., Cruz L.J., Olivera B.M., Tsien R.W., Yoshikami D. ω-conotoxin: Direct and persistent blockade of specific types of calcium channels in neurons but not muscle. Proc. Natl. Acad. Sci. 84:1987;4327-4331.
25. Möckel V., Fischer G. Vulnerability to excitotoxic stimuli of cultured rat hippocampal neurons containing the calcium-binding proteins calretinin and calbindin D28K. Brain Res. 648:1994;109-120.
26. Monn J.A., Valli M.J., Massey S.M., Wright R.A., Salhoff C.R., Johnson B.G., Howe T., Alt C.A., Rhodes G.A., Robey R.L., Griffey K.R., Tizzano J.P., Kallman M.J., Helton D.R., Schoepp D.D. Design, synthesis, and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): A potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxiolytic properties. J. Med. Chem. 40:1997;528-537.
27. Nakajima Y., Iwakabe H., Akazawa C., Nawa H., Shigemoto R., Mizuno N., Nakanishi S. Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate. J. Biol. Chem. 268:1993;11868-11873.
28. Neki A., Ohishi H., Kaneko T., Shigemoto R., Nakanishi S., Mizuno N. Metabotropic glutamate receptors mGluR2 and mGluR5 are expressed in two non-overlapping populations of Golgi cells in the rat cerebellum. Neuroscience. 75:1996;815-826.
29. Okamoto N., Hori S., Akazawa C., Hayashi Y., Shigemoto R., Mizuno N., Nakanishi S. Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction. J. Biol. Chem. 269:1994;1231-1236.
30. Ornstein P.L., Bleisch M.B., Arnold R.A., Wright B.G., Johnson J.P., Tizzano D.R., Helton M.J., Kallman M.J., Schoepp D.D. Novel Antagonists for metabotropic glutamate receptors. Neuropharmacology. 35:1996;A22.
31. Pin J.P., Weiss S., Sebben M., Kemp D.E., Bockaert J. Release of endogenous amino acids from striatal neurones in primary culture. J. Neurochem. 47:1986;594-603.
32. Pin J.P., Bockaert J. Multiple voltage-sensitive calcium channels are probably involved in endogenous GABA release from striatal neurones differentiated in primary culture. Naunyn-Schmiedeberg's Arch. Pharmacol. 336:1987;190-196.
33. Pin J.P., Bockaert J. Two distinct mechanisms, differentially affected by excitatory amino acids, trigger GABA release from fetal mouse striatal neurones in primary culture. J. Neurosci. 9:1989;648-656.
34. 2+ channels involved in GABA release from striatal neurons in culture. Eur. J. Pharmacol. 188:1990;81-84.
35. Sahara Y., Westbrook G.L. Modulation of calcium currents by a metabotropic glutamate receptor involves fast and slow kinetic components in cultured hippocampal neurons. J. Neurosci. 13:1993;3041-3050.
36. Salt T.E., Eaton S.A. Modulation of sensory neurone excitatory and inhibitory responses in the ventrobasal thalamus by activation of metabotropic excitatory amino acid receptors. Neuropharmacology. 34:1995;1043-1051.
37. Saugstad J.A., Kinzie J.M., Mulvihill E.R., Segerson T.P., Westbrook G.L. Cloning and expression of a new member of the L-2-amino-4-phosphonobutyric acid-sensitive class of metabotropic glutamate receptors. Mol. Pharmacol. 45:1994;367-372.
38. Saugstad J.A., Kinzie J.M., Shinohara M.M., Segerson T.P., Westbrook G.L. Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile. Mol. Pharmacol. 51:1997;119-125.
39. Sayer R.J., Schwindt P.C., Crill W.E. Metabotropic glutamate receptor-mediated suppression of L-type calcium current in acutely isolated neocortical neurons. J. Neurophysiol. 68:1992;833-842.
40. 2+ channels involved? Neuropharmacology. 34:1995;1549-1557.
41. Schoepp D.D., Johson B.G., Wright R.A., Salhoff C.R., Mayne N.G., Wu S., Cockerham S.L., Burnett J.P., Belagaje R., Bleakman D., Monn J.A. LY354740 is a potent and highly selective group II metabotropic glutamate receptor agonist in cells expressing human glutamate receptors. Neuropharmacology. 36:1996;1-11.
42. 2+ currents in pyramidal cortical neurones. Neuroreport. 7:1996;421-424.
43. Tanabe Y., Nomura A., Masu M., Shigemoto R., Mizuno N., Nakanishi S. Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4. J. Neurosci. 13:1993;1372-1378.
44. Thomsen C., Kristensen P., Mulvihill E., Haldeman B., Suzdak P.D. L-2-amino-4-phosphonobutyrate (L-AP4) is an agonist at the type IV metabotropic glutamate receptor which is negatively coupled to adenylate cyclase. Eur. J. Pharmacol. 227:1992;361-362.
45. Thomsen C., Suzdak P.D. Serine-O-phosphate has affinity for type IV, but not type I, metabotropic glutamate receptor. Neuroreport. 4:1993;1099-1101.
46. Trombley P.Q., Westbrook G.L. L-AP4 inhibits calcium currents and synaptic transmission via a G-protein-coupled glutamate receptor. J. Neurosci. 12:1992;2043-2050.
47. 3H]-Aminobutyric acid from striatal neurons in primary culture. J. Pharmacol. Exp. Ther. 252:1990;380-386.
48. Yoshino M., Sawada S., Yamamoto C., Kamiya H. A metabotropic glutamate receptor agonist DCG-IV suppresses synaptic transmission at mossy fiber pathway of the guinea pig hippocampus. Neurosci. Lett. 207:1996;70-72.
49. Zamponi G.W., Bourinet E., Nelson D., Nargeot J., Snutch T.P. Crosstalk between G proteins and protein kinase C mediated by the calcium channel α1 subunit. Nature. 385:1997;442-446.