Ambewelamides A and B, antineoplastic epidithiapiperazinediones isolated from the lichen Usnea sp.

Tetrahedron Letters

Volumn 39, Issue 52, 1998, Pages 9579-9582

  Williams, David E ^a   Bombuwala, Karunananda ^b   Lobkovsky, Emil ^c   De Silva, E Dilip ^d   Karunaratne, Veranja ^b   Allen, Theresa M ^e   Clardy, Jon ^c   Andersen, Raymond J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF PERADENIYA   (Sri Lanka)

^c Department of Population Medicine and Diagnostic Sciences   (United States)

^d UNIVERSITY OF COLOMBO   (Sri Lanka)

^e UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMBEWELAMIDE A; AMBEWELAMIDE B; ANTINEOPLASTIC AGENT; EPIDITHIAPIPERAZINEDIONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL LINE; LICHENS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; SRI LANKA; X RAY CRYSTALLOGRAPHY;

EID: 0032564593     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)02277-1     Document Type: Article

References (19)

1. 1) This paper is dedicated to Professor Edward Piers on the occasion of his 60th birthday
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9. 3): δ 162.8 (C-1/C-1′), 75.9 (C-2/C-2′), 36.9 (C-3/C-3′), 137.4/137.3 (C-4/C-4′), 120.3/120.1 (C-5/C-5′), 65.0/64.7 (C-6/C-6′), 51.0/51.0 (C-7/C-7′), 54.8 (C-8/C-8′), 56.2/56.2 (C-9/C-9′), 170.6 (C-10), 20.7 (C-11), 173.3 (C-12), 35.8 (C-13), 18.4 (C-14), 13.6 (C-15) ppm.
10. 3): δ 162.9 (C-1/C-1′), 75.9 (C-2/C-2′), 36.9 (C-3/C-3′), 137.4/137.3 (C-4/C-4′), 120.3/120.1 (C-5/C-5′), 65.0/64.7 (C-6/C-6′), 51.0/51.0 (C-7/C-7′), 54.8 (C-8/C-8′), 56.2/56.2 (C-9/C-9′), 170.6 (C-10), 20.7 (C-11), 173.5 (C-12), 34.0 (C-13), 24.6 (C-14), 31.2 (C-15), 22.3 (C-16), 13.9 (C-17) ppm.
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