Novel thiodiketopiperazine fungal metabolites as epidermal growth factor receptor antagonists

Tetrahedron Letters

Volumn 38, Issue 6, 1997, Pages 911-914

  Hegde, Vinod R ^a   Dai, Ping ^a   Patel, Mahesh ^a   Das, Pradip R ^a   Puar, Mohindar S ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; PIPERAZINE DERIVATIVE; SCH 64874; SCH 64875; SCH 64877; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG RECEPTOR BINDING; DRUG SCREENING; FERMENTATION; FRACTIONATION; FUNGUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0031562074     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02457-4     Document Type: Article

References (5)

1. 4K 807.1516.
2. 2. Nagarajan, R.; Huchstep, L. L.; Lively, D. H.; Delong, D. C. ; Marsh, M. M.; Neuss, N. J. Am. Chem Soc. 1968, 90, 2980-2982. (figure presented) * #s on protons in the structure refers to signals
3. 3. Neuss, N.; Nagarajan, R.; Mosloy, B. B.; Huchstep, L. L. Tetrahedron, Lett. 1968, 42, 4467-4471.
4. 4. Nagarajan, R.; Neuss, N.; Marsh, M. M. J. Am. Chem Soc. 1968, 90, 6518.
5. 5. Cosulich, D. B.; Nelson, N. R.; Van den Hende, J. H. J. Am. Chem Soc. 1968, 90, 6519-6521.