Inhibition of intrathymic T cell development by expression of a transgenic antagonist peptide

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 24, 1998, Pages 14349-14354

  Levelt, Christiaan N ^a   Mizoguchi, Emiko ^b   Huang, Xin ^a   Zacks, Rebecca ^a   Bhan, Atul K ^b   Tonegawa, Susumu ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Positive selection; Thymus

Indexed keywords

LIGAND; PEPTIDE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE; THYMUS; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; ATP-BINDING CASSETTE TRANSPORTERS; CD8-POSITIVE T-LYMPHOCYTES; DNA PRIMERS; H-2 ANTIGENS; HISTOCOMPATIBILITY ANTIGENS CLASS I; IN SITU NICK-END LABELING; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PEPTIDES; POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; THYMUS GLAND;

ANIMALIA; MUS MUSCULUS;

EID: 0032564353     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.24.14349     Document Type: Article

References (46)

1. Kisielow, P., Teh, H. S., Bluthmann, H. & von Boehmer, H. (1988) Nature (London) 335, 730-733.
2. Ashton-Rickardt, P., van Kaer, L., Schumacher, T. N., Ploegh, H. L. & Tonegawa, S. (1993) Cell 73, 1041-1049.
3. Hogquist, K. A., Gavin, M. A. & Bevan, M. J. (1993) J. Exp. Med. 177, 1469-1473.
4. Sebzda, E., Wallace, V. A., Mayer, J., Yeung, R. S., Mak, T. W. & Ohashi, P. S. (1994) Science 263, 1615-1618.
5. Hogquist, K. A., Jameson, S. C., Heath, W. R., Howard, J. L., Bevan, M. J. & Carbone, F. R. (1994) Cell 76, 17-27.
6. Ashton-Rickardt, P., Bandeira, A., Delaney, J. R., van Kaer, L., Pircher, H. P., Zinkernagel, R. M. & Tonegawa, S. (1994) Cell 76, 651-663.
7. Lyons, D. S., Lieberman, S. A., Hampl, I., Boniface, J. J., Chien, Y., Berg, L. J. & Davis, M. M. (1996) Immunity 5, 53-61.
8. Alam, S. M., Travers, P. J., Wung, J. L., Nasholds, W., Redpath, S., Jameson, S. C. & Gascoigne, N. R. (1996) Nature (London) 381, 616-620.
9. Matsui, K., Boniface, J. J., Steffner, P., Reay, P. A. & Davis, M. M. (1994) Proc. Natl. Acad. Sci. USA 91, 12862-12866.
10. Corr, M., Slanetz, A. E., Boyd, L. F., Jelonek, M. T., Khilko, S., al Ramadi, B., Kim, Y. S., Maher, S. E., Bothwell, A. L. & Margulies, D. H. (1994) Science 265, 946-949.
11. Rabinowitz, J. D., Beeson, C., Lyons, D. S., Davis, M. M. & McConnell, H. M. (1996) Proc. Natl. Acad. Sci. USA 93, 1401-1405.
12. Reich, Z., Boniface, J. J., Lyons, D. S., Borochov, N., Wachtel, E. J. & Davis, M. M. (1996) Nature (London) 387, 617-620.
13. Hogquist, K. A., Tomlinson, A. J., Kieper, W. C., McGargill, M. A., Hart, M. C., Naylor, S. & Jameson, S. C. (1997) Immunity 6, 389-399.
14. Sebzda, E., Kundig, T. M., Thomson, C. T., Aoki, K., Mak, S. Y., Mayer, J. P., Zamborelli, T., Nathenson, S. G. & Ohashi, P. S. (1996) J. Exp. Med 183, 1093-1104.
15. Hogquist, K. A., Jameson, S. C. & Bevan, M. J. (1995) Immunity 3, 79-86.
16. Girao, C., Hu, Q., Sun, J. & Ashton-Rickardt, P. (1997) J. Immunol. 159, 4205-4211.
17. Mamalaki, C., Elliott, J., Norton, T., Yannoutsos, N., Townsend, A. R., Chandler, P., Simpson, E. & Kioussis, D. (1993) Dev. Immunol 3, 159-174.
18. Snyder, H. L., Yewdell, J. W. & Bennink, J. R. (1994) J. Exp. Med. 180, 2389-2394.
19. Elliott, T., Willis, A., Cerundolo, V. & Townsend, A. (1995) J. Exp. Med. 181, 1481-1491.
20. van Kaer, L., Ashton-Rickardt, P., Ploegh, H. L. & Tonegawa, S. (1992) Cell 71, 1205-1214.
21. Mombaerts, P., Iacomini, J., Johnson, R. S., Herrup, K., Toncgawa, S. & Papaioannou, V. E. (1992) Cell 68, 869-877.
22. Lafaille, J. J., Nagashima, K., Katsuki, M. & Tonegawa, S. (1994) Cell 78, 399-408.
23. Wunderlich, J. & Shearer, G. (1992) in Current Protocols in Immunology, eds. Coligan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M. & Stober, W. (Wiley, New York), pp. 3.11.14-13.11.17.
24. Clayton, L. K., Ghendler, Y., Mizoguchi, E., Patch, R. J., Ocain, T. D., Orth, K., Bhan, A. K., Dixit, V. M. & Reinherz, E. L. (1997) EMBO J. 16, 2282-2293.
25. Vasquez, N. J., Kaye, J. & Hedrick, S. M. (1992) J. Exp. Med. 175, 1307-1316.
26. Gollob, K. J. & Palmer, E. (1992) Proc. Natl. Acad. Sci. USA 89, 5138-5141.
27. Surh, C. D. & Sprent, J. (1994) Nature (London) 372, 100-103.
28. Kishimoto, H., Surh, C. D. & Sprent, J. (1995) J. Exp. Med 181, 649-655.
29. Page, D. M., Alexander, J., Snoke, K., Appella, E., Sette, A., Hedrick, S. M. & Grey, H. M. (1994) Proc. Natl. Acad. Sci. USA 91, 4057-4061.
30. Wack, A., Ladyman, H. M., Williams, O., Roderick, K., Ritter, M. A. & Kioussis, D. (1996) Int. Immunol. 8, 1537-1548.
31. Swat, W., Dessing, M., von Boehmer, H. & Kisielow, P. (1993) Eur. J. Immunol. 23, 739-746.
32. Brandie, D., Muller, S., Muller, C., Hengartner, H. & Pircher, H. (1994) Eur. J. Immunol. 24, 145-151.
33. Williams, O., Tanaka, Y., Bix, M., Murdjeva, M., Littman, D. R. & Kioussis, D. (1996) Eur. J. Immunol. 26, 532-538.
34. Spain, L. M., Jorgensen, J. L., Davis, M. M. & Berg, L. J. (1994) J. Immunol. 152, 1709-1717.
35. Sloan, L. J., Shaw, A. S., Rothbard, J. B. & Allen, P. M. (1994) Cell 79, 913-922.
36. Madrenas, J., Wange, R. L., Wang, J. L., Isakov, N., Samelson, L. E. & Germain, R. N. (1995) Science 267, 515-518.
37. Windhagen, A., Scholz, C., Hollsberg, P., Fukaura, H., Sette, A. & Hafler, D. A. (1995) Immunity 2, 373-380.
38. Hashimoto, K., Sohn, S. J., Levin, S. D., Tada, T., Perlmutter, R. M. & Nakayama, T. (1996) J. Exp. Med. 184, 931-943.
39. Molina, T. J., Kishihara, K., Siderovski, D. P., van Ewijk. W., Narendran, A., Timms, E., Wakeham, A., Paige, C. J., Hartmann, K. U., Veillette, A., et al. (1992) Nature (London) 357, 161-164.
40. Negishi, I., Motoyama, N., Nakayama, K., Nakayama, K., Senju, S., Hatakeyama, S., Zhang, Q., Chan, A. C. & Loh, D. Y. (1995) Nature (London) 376, 435-438.
41. Evavold, B. D., Sloan-Lancaster, K. & Allen, P. M. (1993) Immunol Today 14, 602-609.
42. Pawlowski, T. J., Singleton, M. D., Loh, D. Y., Berg, R. & Staerz, U. D. (1996) Eur. J. Immunol. 26, 851-857.
43. O'Rourke, A. M., Rogers, J. & Mescher, M. F. (1990) Nature (London) 346, 187-189.
44. Garcia, K. C., Scott, C. A., Brunmark, A., Carbone, F. R., Peterson, P. A., Wilson, I. A. & Teyton, L. (1996) Nature (London) 384, 577-581.
45. Hampl, J., Chien, Y. H. & Davis, M. M. (1997) Immunity 7, 379-385.
46. Madrenas, J., Chau, L. A., Smith, J., Bluestone, J. A. & Germain, R. (1997) J. Exp. Med. 185, 219-229.