Modulation of cardiac Na+ current phenotype by β1-subunit expression

Circulation Research

Volumn 83, Issue 4, 1998, Pages 441-447

  Kupershmidt, Sabina ^a   Yang, Tao ^a   Roden, Dan M ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Myocyte; Na+ current; subunit

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; PROTEIN SUBUNIT;

ANIMAL CELL; ARTICLE; ELECTROPHYSIOLOGY; EXCITATION; FEMALE; HEART MUSCLE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SODIUM CURRENT;

EID: 0032563712     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.83.4.441     Document Type: Article

References (29)

1. Zhang JF, Robinson RB, Siegelbaum SA. Sympathetic neurons mediate developmental change in cardiac sodium channel gating through long-term neurotransmitter action. Neuron. 1992;9:97-103.
2. Lipka LJ, Siegelbaum SA, Robinson RB, Berman MF. An analogue of cAMP mimics developmental change in neonatal rat ventricular myocyte sodium current kinetics. Am J Physiol. 1996;270:H194-H199.
3. Yang T, Roden DM. Regulation of sodium current development in cultured atrial tumor myocytes (AT-1 cells). Am J Physiol. 1996;271: H541-H547.
4. Field LJ. Atrial natriuretic factor-SV40 T antigen transgenes produce tumors and cardiac arrhythmias in mice. Science. 1988;239:1029-1033.
5. Steinhelper ME, Lanson NA Jr, Dresdner KP, Delcarpio JB, Wit AL, Claycomb WC, Field LJ. Proliferation in vivo and in culture of differentiated adult atrial cardiomyocytes from transgenic mice. Am J Physiol. 1990;259:H1826-H1834.
6. Delcarpio JB, Lanson NA Jr, Field LJ, Claycomb WC. Morphological characterization of cardiomyocytes isolated from a transplantable cardiac tumor derived from transgenic mouse atria (AT-1 cells). Circ Res. 1991; 69:1591-1600.
7. Lanson NA, Glembotski CC, Steinhelper ME, Field LJ, Claycomb WC. Gene expression and atrial natriuretic factor processing and secretion in cultured AT-1 cardiac myocyles. Circulation. 1992;85:1835-1841.
8. + channel mRNA in cultured atrial cardiac myocytes (AT-1 cells). Circ Res. 1994;75:870-878.
9. 1 subunit of the rat brain sodium channel. Science. 1992;256:839-842.
10. Kupershmidt S, Yang T, Roden DM. Inhibition of beta-subunit expression prevents development of a mature sodium current phenotype in cultured heart cells [abstract]. Circulation. 1996;94(suppl I):I-287-1-287.
11. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Press; 1989.
12. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162:156-159.
13. Balser JR, Bennett PB, Roden DM. Time-dependent outward current in guinea pig ventricular myocytes: gating kinetics of the delayed rectifier. J Gen Physiol. 1990;96:835-863.
14. 1 subunit mRNA expressed in adult human skeletal muscle, heart, and brain is encoded by a single gene. J Biol Chem. 1994;269:7571-7578.
15. 1 subunits. J Biol Chem. 1995;270: 25696-25701.
16. Nuss HB, Chiamvimonvat N, Pérez-García MT, Tomaselli GF, Marban E. Functional association of the β1 subunit with human cardiac (hH1) and rat skeletal muscle (μ1) sodium channel α subunits expressed in Xenopus oocytes. J. Gen. Physiol. 1995;106:1171-1191.
17. + channel subunits and Ig domains. Nature. 1996;383:307-308.
18. Isom LL, Scheuer T, Brownstein AB, Ragsdale DS, Murphy BJ, Catterall WA. Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell line. J Biol Chem. 1995;270: 3306-3312.
19. Lue WM, Boyden PA. Abnormal electrical properties of myocytes from chronically infarcted canine heart: alterations in Vmax and the transient outward current. Circulation. 1992;85:1175-1188.
20. + current in cultured adult human atrial myocytes. Circ Res. 1997;80:572-579.
21. Roy ML, Saal D, Perney T, Sontheimer H, Waxman SG, Kaczmarek LK. Manipulation of the delayed rectifier Kv1.5 potassium channel in glial cells by antisense oligodeoxynucleolides. Glia. 1996;18:177-184.
22. Chung S, Saal DB, Kaczmarek LK. Elimination of potassium channel expression by antisense oligonucleotides in a pituitary cell line. Proc Natl Acad Sci U S A. 1995;92:5955-5959.
23. Wagner JA, McDonald TV, Nghiem PT, Lowe AW, Schulman H, Gruenert DC, Stryer L, Gardner P. Antisense oligodeoxynucleotides to the cystic fibrosis transmembrane conductance regulator inhibit cAMP-activated but not calcium-activated chloride currents. Proc Natl Acad Sci U S A. 1992;89:6785-6789.
24. + current. Circ Res. 1995;77:1246-1253.
25. McDonald TV, Yu Z, Ming Z, Palma E, Meyers MB, Wang KW, Goldstein, SA, Fishman GI. A minK-HERG complex regulates the cardiac potassium current I(Kr). Nature. 1997;388:289-292.
26. Wagner RW. Gene inhibition using antisense oligodeoxynucleotides. Nature. 1994;372:333-335.
27. Ghosh MK, Cohen JS. Oligodeoxynucleotides as antisense inhibitors of gene expression. Prog Nucleic Acid Res Mol Biol. 1992;42:79-126.
28. 2+ channels in embryonic mouse heart. Circ Res. 1996;78: 371-378.
29. Sun LS, Legato MJ, Rosen TS, Steinberg SF, Rosen MR. Sympathetic innervation modulates ventricular impulse propagation and repolarization in the immature rat heart. Cardiovasc Res. 1993;27:459-463.