Manipulation of the delayed rectifier Kv1.5 potassium channel in glial cells by antisense oligodeoxynucleotides

GLIA

Volumn 18, Issue 3, 1996, Pages 177-184

  Roy, Mary Louise ^a,b   Saal, Daniel ^a   Perney, Teresa ^a,c   Sontheimer, Harald ^a,d   Waxman, Stephen G ^a   Kaczmarek, Leonard K ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Astrocyte; Immunohistochemistry; Phosphorothioate deoxynucleotide

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; MESSENGER RNA; POTASSIUM CHANNEL;

ANIMAL; ARTICLE; ASTROCYTE; BIOSYNTHESIS; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CYTOLOGY; DRUG EFFECT; ELECTROPHYSIOLOGY; FLUORESCENCE MICROSCOPY; GLIA; IMMUNOHISTOCHEMISTRY; METABOLISM; PATCH CLAMP; PHYSIOLOGY; RAT; SERODIAGNOSIS; SPINAL CORD; SPRAGUE DAWLEY RAT;

ANIMALS; ASTROCYTES; ELECTROPHYSIOLOGY; IMMUNOHISTOCHEMISTRY; ION CHANNEL GATING; MEMBRANE POTENTIALS; MICROSCOPY, FLUORESCENCE; NEUROGLIA; OLIGONUCLEOTIDES, ANTISENSE; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; PRECIPITIN TESTS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SPINAL CORD;

EID: 0030293938     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1136(199611)18:3<177::AID-GLIA2>3.0.CO;2-X     Document Type: Article

References (32)

1. Barres, B.A., Chun, L.L.Y., and Corey, D.P. (1990) Ion channels in vertebrate glia. Annu. Rev. Neurosci., 13:441-474.
2. Black, J.A., Sontheimer, H., and Waxman, S.G. (1993) Spinal cord astrocytes in vitro: Phenotypic diversity and sodium channel immunoreactivity. Glia, 7:272-285.
3. Caceres, A. and Kosik, K.S. (1990) Inhibition of neunte polarity by tau antisense oligodeoxynucleotide in primary cerebellar neurons. Nature, 343:461-463.
4. O: Antisense oligonucleotide studies. J. Physiol., 470:1-11.
5. Chung, S., Saal, D.B., and Kaczmarek, L.K. (1995) Elimination of potassium channel expression by antisense oligodeoxynucleotide in a pituitary cell line. Proc. Natl. Acad. Sci., USA, 92:5955-5959.
6. + channel inactivation gating by the cAMP-dependent protein kinase. Neuron, 12:1097-1109.
7. Gewirtz, A.M., and Calabretta, B. (1988) Ac-myb antisense oligodeoxynucleotide inhibits normal human hematopoiesis in vitro. Science, 242:1303-1306.
8. Hamill, O.P., Marty, A., Neher, E., Sakmann, B., and Sigworth, F.J. (1981) Improved patch clamp technique for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch., 391:85-100.
9. Harlow, E. and Lane, D. (1988) Antibodies: A Laboratory Manual. Cold Spring Harbor Press, Cold Spring Harbor, NY.
10. Isacoff, E., Papazian, D., Timpe, L., Jan, Y.N., and Jan, L.Y. (1990) Molecular studies of voltage-gated potassium channels. Cold Spring Harbor Sympo. Quant. Biol., 55:9-17.
11. Kalman, M. and Hajos, F. (1989) Distribution of glial fibrillary acidic protein (GFAP) immunoreactive astrocytes in the rat brain. I. Forebrain. Exp. Brain Res., 78:147-163.
12. Karwoski, C.J., Lu, H.-K., and Newman, E.A. (1989) Spatial buffering of light-evoked potassium increases by retinal Müller (glial) cells. Science, 244:578-580.
13. Kuffler, S.W., Nicholls, J.G., and Orkand, R.K. (1966) Physiological properties of glial cells in the central nervous system of amphibia. J. Neurophysiol., 29:768-787.
14. Listerud, M., Brussaard, A.B., Devay, P., Colman, D.R., and Role, L.W. (1991) Functional contribution of neuronal AChR subunits revealed by antisense oligodeoxynucleotide. Science, 254:1518-1521.
15. Marcus-Sekura, C.J. (1988) Techniques for using antisense oligodeoxyribonucleotides to study gene expression. Anal. Biochem., 172: 289-295.
16. Mi, H., Deerinck, T., Ellisman, M.H., and Schwartz, T.L. (1995) Differential distribution of closely related potassium channels in rat Schwann cells. J. Neurosci., 15:3761-3774.
17. Newman, E.A. (1984) Regional specialization of retinal glial cell membrane. Nature, 309:155-157.
18. Newman, E.A. (1985) Membrane physiology of retinal glial (Müller) cells. J. Neurosci., 5:2225-2239.
19. Newman, E.A. (1986) High potassium conductance in astrocyte endfeet. Science, 233:453-454.
20. Newman, E.A. (1987) Distribution of potassium conductance in mammalian Müller (glial) cells: A comparative study. J. Neurosci., 7:2423-2432.
21. Newman, E.A. (1993) Inward-rectifying potassium channels in retinal glial (Müller) cells. J. Neurosci., 13:3333-3345.
22. i. Neuroreport, 6:193-196.
23. + currents in rat spinal cord astrocytes. J. Neurophysiol., 73:333-345.
24. + channels altered by the presence of a beta subunit. Nature, 369:289-294.
25. Roy, M.L. and Sontheimer, H. (1993) Differential modulation of potassium current by protein kinase A activators in rat spinal cord astrocytes. Soc. Neurosci. Abst., 19:688.
26. Roy, M.-L. and Sontheimer, H. (1995) β-Adrenergic modulation of glial inwardly rectifying potassium channels. J. Neurochem., 64: 1576-1584.
27. Smith, D.B. and Johnson, K.S. (1988) Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene, 67:31-40.
28. Sontheimer, H. (1992) Astrocytes as well as neurons, express a diversity of ion channels. Can. J. Physiol. Pharmacol., 70:S223-238.
29. Sontheimer, H. (1994) Voltage-dependent ion channels in glial cells. Glia, 11:156-172.
30. + channels. J. Neurophysiol., 68:985-1000.
31. Swanson, R., Marshall, J., Smith, J.S., Williams, J.B., Boyle, M.B., Folander K., Luneau, C.J., Antanavage, J., Oliva, C., Buhrow, S.A., Bennett, C., Stein, R.B., and Kaczmarek, L.K. (1990) Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain. Neuron, 4:929-939.
32. Thio, C.L., Waxman, S.G., and Sontheimer, H. (1993) Ion channels in spinal cord astrocytes in vitro. III. Modulation of channel expression by coculture with neurons and neuron conditioned media. J. Neurophysiol., 69:819-831.