Type I protein C deficiency caused by disruption of a hepatocyte nuclear factor (HNF)-6/HNF-1 binding site in the human protein C gene promoter

Journal of Biological Chemistry

Volumn 273, Issue 17, 1998, Pages 10168-10173

  Spek, C Arnold ^a,c   Lannoy, Vincent J ^b,d   Lemaigre, Frédéric P ^b,e   Rousseau, Guy G ^b   Bertina, Rogier M ^a   Reitsma, Pieter H ^a,c  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF LOUVAIN MEDICAL SCHOOL   (Belgium)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d Fonds pour Form Rech dans l'I ^*  (Belgium)

^e FUND FOR SCIENTIFIC RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR FACTOR; NUCLEAR FACTOR I; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; BINDING SITE; BLOOD CLOTTING; DNA FLANKING REGION; DNA TRANSFECTION; GENE ACTIVITY; GENE STRUCTURE; HUMAN; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN C DEFICIENCY; STRUCTURE ACTIVITY RELATION; VEIN THROMBOSIS;

ANIMALS; BINDING SITES; COS CELLS; DNA-BINDING PROTEINS; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HEPATOCYTE NUCLEAR FACTOR 1-BETA; HEPATOCYTE NUCLEAR FACTOR 6; HOMEODOMAIN PROTEINS; HUMANS; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN C; PROTEIN C DEFICIENCY; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0032562761     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.17.10168     Document Type: Article

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