Characterization of human protein C gene promoter: Insights from natural human mutants

DNA and Cell Biology

Volumn 15, Issue 11, 1996, Pages 907-919

  Tsay, Woei ^a  

^a Department of Internal Medicine ^*  (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN C;

ANIMAL CELL; ARTICLE; BINDING SITE; CASE REPORT; GENE CONTROL; GENE MUTATION; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN C DEFICIENCY; REGULATORY MECHANISM; TRANSCRIPTION REGULATION; VEIN THROMBOSIS;

ANIMALIA;

EID: 0029801303     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.1996.15.907     Document Type: Article

References (7)

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2. BERG, L.-P., WHITE, D.A., ALHAQ, A., KAKKAR, V.V., and COOPER, D.N. (1994). Disruption of a binding site for hepatocyte nuclear factor-1 (HNF-1) in the protein C (PROC) gene promoter is associated with hereditary thrombophilia. Hum. Mol. Genet. 3, 2147-2152.
3. BOHINSKI, R.J., di LAURO, R., WHITSETT, J.A. (1994). The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis. Mol. Cell. Biol. 14, 5671-5681.
4. BRENNAN, R.G. (1993). The winged-helix DNA-binding motif: another helix-tum-helix takeoff. Cell 74, 773-776.
5. BROEKMANS, A.W., CONARD, J., van WEYENBERG, R.G., HORELLOU, M.H., KLUFT, C., and BERTINA, R.M. (1987). Treatment of hereditary protein C deficiency with stanozolol. Thromb. Haemost. 57, 20-24.
6. CHOUARD, T., BLUMENFELD, M., BACH, I., VANDEKERCKHOVE, J., CEREGHINI, S., and YANIV, M. (1990). A distal dimerization domain is essential for DNA-binding by the atypical HNF1 homeodomain. Nucleic Acids Res. 18, 5853-5863.
7. DÄHLBACK, B. (1995). Inherited thrombophilia: resistance to activated protein C as a pathogenic factor of venous thromboembolism. Blood 3, 607-614.