Early Embryo Loss Is Associated with the Prior Expression of Macrophage Activation Markers in the Decidua

Journal of Immunology

Volumn 158, Issue 10, 1997, Pages 4886-4892

  Haddad, Elias K ^a   Duclos, Alain J ^a   Lapp, Wayne S ^a   Baines, Malcolm G ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BREEDING; CBA MOUSE; DECIDUA; EMBRYO DEATH; FEMALE; GENE EXPRESSION; GENETICS; IMMUNOLOGY; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; METABOLISM; MOUSE; PREGNANCY;

ANIMALS; DECIDUA; EMBRYO LOSS; FEMALE; GENE EXPRESSION; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED CBA; NITRIC OXIDE SYNTHASE; PREGNANCY; PREGNANCY, ANIMAL; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031570095     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Clark, D. A., M. R. McDermott, and M. R. Szewczuk. 1980. Impairment of host-versus-graft reaction in pregnant mice. II. Selective suppression of cytotoxic T-cell generation correlates with soluble suppressor activity and with successful allogeneic pregnancy. Cell. Immunol. 52:106.
2. de Fougerolles, A. R., and M. G. Baines. 1987. Modulation of the natural killer cell activity in pregnant mice alters the spontaneous abortion rate. J. Reprod. Immunol. 11:147.
3. Kinsky, R. G., G. Delage, N. Rosin, M. N. Thang, M. Hoffmann, and G. Chaouat. 1990. A murine model of NK cell mediated resorption. Am. J. Reprod. Immunol. 23:73.
4. Duclos, A. J., D. K. Pomerantz, and M. G. Baines. 1994. Relationship between decidual leukocyte infiltration and spontaneous abortion in a murine model of early fetal resorption. Cell. Immunol. 159:184.
5. Duclos, A. J., E. K. Haddad, and M. G. Baines. 1995. Presence of activated macrophages in a murine model of early embryo loss. Am. J. Reprod. Immunol. 33:354.
6. Baines, M. G., A. J. Duclos, A. R. Defougerolles, and R. L. Gendron. 1996. Immunological prevention of spontaneous early embryo resorption is mediated by non-specific immunostimulation. Am. J. Reprod. Immunol. 35:34.
7. Gendron, R. L., and M. G. Baines. 1988. Infiltrating decidual natural killer cells are associated with spontaneous abortion in mice. Cell. Immunol. 113:261.
8. Haddad, E. K., A. J. Duclos, and M. G. Baines. 1995. Early embryo loss is associated with local production of nitric oxide by decidual mononuclear cells. J. Exp. Med. 182:1143.
9. Bredt, D. S., and S. H. Snyder. 1990. Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc. Natl. Acad. Sci. USA 87:682.
10. Stuehr, D. J., H. J. Cho, N. S. Kwon, M. F. Weise, and C. F. Nathan. 1991. Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD-and FMN-containing flavoprotein. Prof. Natl. Acad. Sci. USA 88:7773.
11. Moncada, S., R. M. Palmer, and E. A. Higgs. 1991. Nitric oxide: physiology, pathophysiology, and pharmacology. Phannacol. Rev. 43:109.
12. Knowles, R. G., and S. Moncada. 1994. Nitric oxide synthases in mammals. Biochem. J. 298:249.
13. Ding, A. H., C. F. Nathan, and D. J. Stuehr. 1988. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 141:2407.
14. Munoz-Fernandez, M. A., M. A. Fernandez, and M. Fresno. 1992. Synergism between tumor necrosis factor-α and interferon-γ on macrophage activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism. Eur. J. Immunol. 22:301.
15. Nathan, C., and Q. W. Xie. 1994. Nitric oxide synthases: roles, tolls, and controls. Cell 78:915.
16. Moncada, S., and A. Higgs. 1993. The L-arginine-nitric oxide pathway. N. Eng. J. Med. 329:2002.
17. Griffiths, M. J., M. Messent, R. J. MacAllister, and T. W. Evans. 1993. Aminoguanidine selectively inhibits inducible nitric oxide synthase. Br. J. Pharmacol. 110:963.
18. Hasan, K., B. J. Heesen, J. A. Corbett, M. L. McDaniel, K. Chang, W. Allison, B. H. Wolffenbuttel, J. R. Williamson, and R. G. Tilton. 1993. Inhibition of nitric oxide formation by guanidines. Eur. J. Pharmacol. 249:101.
19. Joly, G. A., M. Ayres, F. Chelly, and R. G. Kilbourn. 1994. Effects of NG-methyl-L-arginine, NG-nitro-L-arginine, and aminoguanidine on constitutive and inducible nitric oxide synthase in rat aorta. Biochem. Biophys. Res. Comm. 199:147.
20. Sidhu, R. S., and A. P. Bollon. 1993. Tumor necrosis factor activities and cancer therapy - a perspective. Pharmacol. Ther. 57:79.
21. Chaouat, G. 1994. Synergy of lipopolysaccharide and inflammatory cytokines in murine pregnancy: alloimmunization prevents abortion but does not affect the induction of preterm delivery. Cell. Immunol. 157:328.
22. Chaouat, G., E. Menu, D. A. Clark, M. Dy, M. Minkowski, and T. G. Wegmann. 1990. Control of fetal survival in CBA X DBA/2 mice by lymphokine therapy. J. Reprod. Fertil. 89:447.
23. Gendron, R. L., F. P. Nestel, W. S. Lapp, and M. G. Baines. 1990. Lipopolysaccharide-induced fetal resorption in mice is associated with the intrauterine production of tumour necrosis factor-alpha. J. Reprod. Fertil. 90:395.
24. Xie, Q. W., and C. F. Nathan. 1993. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon-gamma and bacterial lipopolysaccharide. Trans. Assoc. Am. Physicians 106:1.
25. Lorsbach, R. B., W. J. Murphy, C. J. Lowenstein, S. H. Snyder, and S. W. Russell. 1993. Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing: molecular basis for the synergy between interferon-γ and lipopolysaccharide. J. Biol. Chem. 268:1908.
26. Weisz, A., S. Oguchi, L. Cicatiello, and H. Esumi. 1994. Dual mechanism for the control of inducible-type NO synthase gene expression in macrophages during activation by interferon-gamma and bacterial lipopolysaccharide: transcriptional and post-transcriptional regulation. J. Biol. Chem. 269:8324.
27. Martin, E., C. F. Nathan, and Q. W. Xie. 1994. Role of interferon regulatory factor 1 in induction of nitric oxide synthase. J. Exp. Med. 180:977.
28. Beutler, B., N. Kronchin, I. Milsark, C. Luedke, and A. Cerami. 1986. Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance. Science 232:977.
29. Gifford, G. E., and M. L. Lohmann-Matthes. 1987. Gamma interferon priming of mouse and human macrophages for induction of tumor necrosis factor alpha production by bacterial lipopolysaccharide. J. Natl. Cancer Inst. 78:121.
30. Duclos, A. J., E. K. Haddad, L. E. Chalifour, and M. G. Baines. 1996. Embryo infiltration by maternal macrophages is associated with selective expression of protooncogenes in a murine model of spontaneous abortion. Biol. Reprod. 54:1088.
31. Degliantoni, G., B. Perussia, L. Mangoni, and G. Trinchieri. 1985. Inhibition of bone marrow colony formation by human natural killer cells and by natural killer cell-derived colony-inhibiting activity. J. Exp. Med. 161:1152.
32. Peters, P. M., J. R. Ortaldo, M. R. Shalaby, L. P. Svedersky, G. E. Nedwin, T. S. Bringman, P. E. Hass, B. B. Aggarwal, R. B. Berberman, D. V. Goeddel, and M. A. Palladino. 1986. NK-sensitive targets stimulate production of TNF-α but not TNF-b by highly purified human peripheral blood large granular lymphocytes. J. Immunol. 137:2592.
33. Chomczynski, P., and N. Sacchi. 1987. Single step method of RNA isolation by acid guanidinium thiocyanate phenol chloroform extraction. J. Anal. Biochem. 162:156.
34. Baines, M. G., K. A. Billingsley, A. R. de Fougerolles, A. J. Duclos, H. J. Olney, D. K. Pomerantz, and R. L. Gendron. 1994. Evaluation of the role of exogenous pathogens on the incidence of embryo loss during early pregnancy in mice. J. Reprod. Immunol. 26:17.
35. Wilcox, A. J., C. R. Weinberg, J. F. O'Connor, D. D. Baird, J. P. Schlatterer, R. E. Canfield, E. G. Armstrong, and B. C. Nisula. 1988. Incidence of early loss of pregnancy. N. Engl. J. Med. 319:189.
36. Roberts, R. M., C. E. Farin, and J. C. Cross. 1990. Trophoblast proteins and maternal recognition of pregnancy. Oxf. Rev. Reprod. Immunol. 12:147.
37. Wegmann, T. G. 1990. The cytokine basis for cross-talk between the maternal immune and reproductive systems. Curr. Opin. Immunol. 2:765.
38. Tangri, S., T. G. Wegmann, H. Lin, and R. Raghupathy. 1994. Maternal antiplacental reactivity in natural, immunologically mediated fetal resorptions. J. Immunol. 152:4903.
39. Yui, J., M. Garcia-Lloret, T. G. Wegmann, and L. J. Guilbert. 1994. Cytotoxicity of tumour necrosis factor-alpha and gamma-interferon against primary human placental trophoblasts. Placenta 15:819.
40. Tangri, S., and R. Raghupathy. 1993. Expression of cytokines in placentas of mice undergoing immunologically mediated spontaneous fetal resorptions. Biol. Reprod. 49:850.
41. Yelavarthi, K. K., H. L. Chen, Y. Yang, J. L. Fishback, and J. S. Hunt. 1991. Tumor necrosis factor alpha mRNA and protein in rat uterine and placental cells. J. Immunol. 146:3840.
42. Chen, H. L., Y. Yang, X. L. Hu, K. K. Yelavarthi, J. L. Fishback, and J. S. Hunt. 1991. Tumor necrosis factor alpha mRNA and protein are present in human placental and uterine cells at early and late stages of gestation. Am. J. Pathol. 139:327.
43. Garcia, F. U., H. L. Chen, Y. Yang, J. L. Pace, X. L. Hu, and J. S. Hunt. 1994. Tumor necrosis factor-alpha mRNA and protein in endometrial tumors: analysis by in situ hybridization and immunocytochemistry. Hum. Pathol. 25:1324.
44. Roby, K. F., and J. S. Hunt. 1994. Mouse endometrial tumor necrosis factor-alpha messenger ribonucleic acid and protein: localization and regulation by estradiol and progesterone. Endocrinology 135:2780.
45. Gendron, R. L., F. P. Nestel, W. S. Lapp, and M. G. Baines. 1991. Expression of tumor necrosis factor alpha in the developing nervous system. Int. J. Neurosci. 60:129.
46. Meurs, E., K. Chong, J. Galabru, N. S. Thomas, I. M. Kerr, B. R. Williams, and A. G. Hovanessian. 1990. Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon. Cell 62: 379.
47. De, M., R. Choudhuri, and G. W. Wood. 1991. Determination of the number and distribution of macrophages, lymphocytes, and granulocytes in the mouse uterus from mating through implantation. J. Leukocyte Biol. 50:252.
48. Jewett, A., and B. Bonavida. 1995. Interferon-α activates cytotoxic function but inhibits interleukin-2-mediated proliferation and tumor necrosis factor-α secretion by immature human natural killer cells. J. Clin. Immunol. 15:35.
49. Handa, K., R. Suzuki, H. Matsui, Y. Shimizu, and K. Kumagai. 1983. NK cells as a responder to IL-2. II. IL-2 induced IFN-γ production. J. Immunol. 130:988.
50. Weigent, D. A., G. J. Stanton, and H. M. Johnson. 1983. Interleukin 2 enhances natural killer cell activity through induction of gamma interferon. Infect. Immun. 41:992.
51. Parr, E. L., L. H. Young, M. B. Parr, and J. D. E. Young. 1990. Granulated metrial gland cells of pregnant mouse uterus are natural killer-like cells that contain perforin and serine esterases. J. Immunol. 145:2365.
52. Parr, E. L., H. L. Chen, M. B. Parr, and J. S. Hunt. 1995. Synthesis and granular localization of tumor necrosis factor-α in activated NK cells in the pregnant mouse uterus. J. Reprod. Immunol. 28:31.
53. Lachapelle, M. H., P. Miron, R. Hemmings, and D. C. Roy. 1996. Endometrial T, B, and NK cells in patients with recurrent spontaneous abortion: altered profile and pregnancy outcome. J. Immunol. 156:4027.