메뉴 건너뛰기




Volumn 12, Issue 12, 1998, Pages 1437-1449

Impairment of B-lymphocyte differentiation induced by dual triggering of the B-cell antigen receptor and CD40 in advanced HIV-1-disease

Author keywords

Apoptosis; B lymphocytes; B cell Ag receptor and CD40 costimulation; Differentiation; HIV 1 infection

Indexed keywords

B LYMPHOCYTE ANTIGEN; CD38 ANTIGEN; CD4 ANTIGEN; CD40 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 2; LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY; PHORBOL ESTER;

EID: 0032552092     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199812000-00005     Document Type: Article
Times cited : (46)

References (64)
  • 1
    • 0020516865 scopus 로고
    • Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome
    • Lane H, Masur H, Edgar LC, Wahlen G, Rook G, Fauci AS: Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome. N Engl J Med 1983, 309:453-458.
    • (1983) N Engl J Med , vol.309 , pp. 453-458
    • Lane, H.1    Masur, H.2    Edgar, L.C.3    Wahlen, G.4    Rook, G.5    Fauci, A.S.6
  • 2
    • 0022545415 scopus 로고
    • Direct polyclonal activation of human B lymphocytes by acquired immunodeficiency virus
    • Schnittman SM, Lane CH, Higgins S, Folks T, Fauci AS: Direct polyclonal activation of human B lymphocytes by acquired immunodeficiency virus. Science 1986, 233:1084-1086.
    • (1986) Science , vol.233 , pp. 1084-1086
    • Schnittman, S.M.1    Lane, C.H.2    Higgins, S.3    Folks, T.4    Fauci, A.S.5
  • 3
    • 0023240958 scopus 로고
    • Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B-lymphocyte activation and immaturity
    • Martinez-Maza O, Crabb E, Mitsuyasu R, Fahey J, Giorgi J: Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B-lymphocyte activation and immaturity. J Immunol 1987, 138:3720-3724.
    • (1987) J Immunol , vol.138 , pp. 3720-3724
    • Martinez-Maza, O.1    Crabb, E.2    Mitsuyasu, R.3    Fahey, J.4    Giorgi, J.5
  • 4
    • 0023930599 scopus 로고
    • Spontaneous in vitro production of virus-specific antibody by lymphocytes from HIV-infected subjects
    • Amadori A, De Rossi A, Faulkner-Valle GP, Chieco-Bianchi L: Spontaneous in vitro production of virus-specific antibody by lymphocytes from HIV-infected subjects. Clin Immunol Immunopathol 1988, 46:342-351.
    • (1988) Clin Immunol Immunopathol , vol.46 , pp. 342-351
    • Amadori, A.1    De Rossi, A.2    Faulkner-Valle, G.P.3    Chieco-Bianchi, L.4
  • 5
    • 0023868764 scopus 로고
    • B-cell activation in HIV infection: Relationship of spontaneous immunoglobulin secretion to various immunological parameters
    • Mizuma H, Litwin S, Zolla-Pazner S: B-cell activation in HIV infection: relationship of spontaneous immunoglobulin secretion to various immunological parameters. Clin Exp Immunol 1988, 71:410-416.
    • (1988) Clin Exp Immunol , vol.71 , pp. 410-416
    • Mizuma, H.1    Litwin, S.2    Zolla-Pazner, S.3
  • 6
    • 0026072996 scopus 로고
    • Analysis of the spontaneous in vitro anti-HIV-1 antibody secretion by peripheral blood mononuclear cells in HIV-1 infection
    • Vendrell JP, Segondy M, Ducos J, et al.: Analysis of the spontaneous in vitro anti-HIV-1 antibody secretion by peripheral blood mononuclear cells in HIV-1 infection. Clin Exp Immunol 1991, 83:197-202.
    • (1991) Clin Exp Immunol , vol.83 , pp. 197-202
    • Vendrell, J.P.1    Segondy, M.2    Ducos, J.3
  • 7
    • 0022492199 scopus 로고
    • Mechanisms of B-cell activation in patients with acquired immunodeficiency syndrome and related disorders
    • Yarchoan R, Redfield R, Broder S: Mechanisms of B-cell activation in patients with acquired immunodeficiency syndrome and related disorders. J Clin Invest 1986, 78:439-447.
    • (1986) J Clin Invest , vol.78 , pp. 439-447
    • Yarchoan, R.1    Redfield, R.2    Broder, S.3
  • 8
    • 0024324637 scopus 로고
    • Longitudinal study of leukocyte functions in homosexual men seroconverted for HIV: Rapid and persistent loss of B cell function after HIV infection
    • Terpstra FG, Al BJL, Roos MTL, et al.: Longitudinal study of leukocyte functions in homosexual men seroconverted for HIV: rapid and persistent loss of B cell function after HIV infection. Eur J Immunol 1989, 19:667-673.
    • (1989) Eur J Immunol , vol.19 , pp. 667-673
    • Terpstra, F.G.1    Al, B.J.L.2    Roos, M.T.L.3
  • 9
    • 0025740289 scopus 로고
    • B-cell activation during HIV-1 infection. III. Down-regulating effect of mitogens
    • Amadori A, Zamarchi R, Veronese ML, et al.: B-cell activation during HIV-1 infection. III. Down-regulating effect of mitogens. AIDS 1991, 5:821-828.
    • (1991) AIDS , vol.5 , pp. 821-828
    • Amadori, A.1    Zamarchi, R.2    Veronese, M.L.3
  • 10
    • 0025129973 scopus 로고
    • Response of mononuclear cells from HIV-infected patients to B-cell mitogens: Correlation with immunological and clinical features of disease progression
    • Edelman AS, Zolla-Pazner S: Response of mononuclear cells from HIV-infected patients to B-cell mitogens: correlation with immunological and clinical features of disease progression. AIDS 1990, 4:859-864.
    • (1990) AIDS , vol.4 , pp. 859-864
    • Edelman, A.S.1    Zolla-Pazner, S.2
  • 11
    • 0023251026 scopus 로고
    • Risk of AIDS related complex and AIDS in homosexual men with persistent HIV antigenaemia
    • De Wolf F, Goudsmit J, Paul AD, et al.: Risk of AIDS related complex and AIDS in homosexual men with persistent HIV antigenaemia. BMJ 1987, 295:569-572.
    • (1987) BMJ , vol.295 , pp. 569-572
    • De Wolf, F.1    Goudsmit, J.2    Paul, A.D.3
  • 12
    • 0026727851 scopus 로고
    • Monitoring of antibodies against human immunodeficiency virus type 1 p25 core protein as prognostic marker
    • Fenouillet E, Blanes N, Coutellier A, Demarquest J, Rozenbaum W, Gluckman JC: Monitoring of antibodies against human immunodeficiency virus type 1 p25 core protein as prognostic marker. J Infect Dis 1992, 166:611-616.
    • (1992) J Infect Dis , vol.166 , pp. 611-616
    • Fenouillet, E.1    Blanes, N.2    Coutellier, A.3    Demarquest, J.4    Rozenbaum, W.5    Gluckman, J.C.6
  • 13
    • 0028889338 scopus 로고
    • Quantitative measures of human immunodeficiency virus-specific antibodies predict progression to AIDS
    • Strathdee SA, Frank JW, Mc Laughlin J, et al.: Quantitative measures of human immunodeficiency virus-specific antibodies predict progression to AIDS. J Infect Dis 1995, 172:1375-1379.
    • (1995) J Infect Dis , vol.172 , pp. 1375-1379
    • Strathdee, S.A.1    Frank, J.W.2    Mc Laughlin, J.3
  • 14
    • 0026027946 scopus 로고
    • Human immunodeficiency virus type-1 infection of homosexual men is accompanied by a decrease in circulating B cells
    • Reddy MM, Goetz RR, Gorman JM, Grieco MH, Chess L, Lederman S: Human immunodeficiency virus type-1 infection of homosexual men is accompanied by a decrease in circulating B cells. J Acquir Immune Defic Syndr 1991, 4:428-434.
    • (1991) J Acquir Immune Defic Syndr , vol.4 , pp. 428-434
    • Reddy, M.M.1    Goetz, R.R.2    Gorman, J.M.3    Grieco, M.H.4    Chess, L.5    Lederman, S.6
  • 15
    • 0026755620 scopus 로고
    • Immune changes in HIV-1 infection: Significant correlations and differences in serum markers and lymphoïd phenotypic antigens
    • Bass HZ, Nishanian P, Hardy WD, et al.: Immune changes in HIV-1 infection: significant correlations and differences in serum markers and lymphoïd phenotypic antigens. Clin Immunol Immunopathol 1992, 64:63-70.
    • (1992) Clin Immunol Immunopathol , vol.64 , pp. 63-70
    • Bass, H.Z.1    Nishanian, P.2    Hardy, W.D.3
  • 17
    • 0026502984 scopus 로고
    • Inhibition of normal B-cell function by human immunodeficiency virus envelope glycoprotein, gp120
    • Chirmule N, Oyaizu N, Kalyanaraman VS, Pahwa S: Inhibition of normal B-cell function by human immunodeficiency virus envelope glycoprotein, gp120. Blood 1992, 79:1245-1259.
    • (1992) Blood , vol.79 , pp. 1245-1259
    • Chirmule, N.1    Oyaizu, N.2    Kalyanaraman, V.S.3    Pahwa, S.4
  • 18
    • 0030008309 scopus 로고    scopus 로고
    • Envelope glycoproteins of human immunodeficiency virus type 1: Profound influences on immune functions
    • Chirmule N, Pahwa S: Envelope glycoproteins of human immunodeficiency virus type 1: profound influences on immune functions. Microbiol Rev 1996, 60:386-406.
    • (1996) Microbiol Rev , vol.60 , pp. 386-406
    • Chirmule, N.1    Pahwa, S.2
  • 19
    • 0025954319 scopus 로고
    • Recombinant gp120 specifically enhances tumor necrosis factor-α production and Ig secretion in B lymphocytes from HIV-1-infected individuals but not from seronegative donors
    • Rieckmann P, Poli G, Fox CH, Kehrl JH, Fauci A: Recombinant gp120 specifically enhances tumor necrosis factor-α production and Ig secretion in B lymphocytes from HIV-1-infected individuals but not from seronegative donors. J Immunol 1991, 147:2922-2927.
    • (1991) J Immunol , vol.147 , pp. 2922-2927
    • Rieckmann, P.1    Poli, G.2    Fox, C.H.3    Kehrl, J.H.4    Fauci, A.5
  • 21
    • 0026598685 scopus 로고
    • HIV-induced, HIV-specific in vitro antibody response by B-cells from HIV-seropositive individuals
    • Delfraissy JF, Wallon C, Boue F, Goujard C, Barré-Sinoussi F, Galanaud P: HIV-induced, HIV-specific in vitro antibody response by B-cells from HIV-seropositive individuals. AIDS 1992, 6:55-63.
    • (1992) AIDS , vol.6 , pp. 55-63
    • Delfraissy, J.F.1    Wallon, C.2    Boue, F.3    Goujard, C.4    Barré-Sinoussi, F.5    Galanaud, P.6
  • 23
    • 0026762942 scopus 로고
    • Transgenic mice and analysis of B-cell tolerance
    • Goodnow CC: Transgenic mice and analysis of B-cell tolerance. Annu Rev Immunol 1992, 10:409-518.
    • (1992) Annu Rev Immunol , vol.10 , pp. 409-518
    • Goodnow, C.C.1
  • 24
    • 0030008694 scopus 로고    scopus 로고
    • The fate of self-reactive B-cells depends primarily on the degree of antigen receptor engagement and availability of T-cell help
    • Fulcher DA, Lyons AB, Korn SL, et al.: The fate of self-reactive B-cells depends primarily on the degree of antigen receptor engagement and availability of T-cell help. J Exp Med 1996, 183:2313-2318.
    • (1996) J Exp Med , vol.183 , pp. 2313-2318
    • Fulcher, D.A.1    Lyons, A.B.2    Korn, S.L.3
  • 25
    • 0030592564 scopus 로고    scopus 로고
    • Expansion or elimination of B cells in vivo: Dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor
    • Rathmell JC, Townsend SE, Xu JC, Flavell RA, Goodnow CC: Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell 1996, 87:319-329.
    • (1996) Cell , vol.87 , pp. 319-329
    • Rathmell, J.C.1    Townsend, S.E.2    Xu, J.C.3    Flavell, R.A.4    Goodnow, C.C.5
  • 26
    • 0028214982 scopus 로고
    • Anergic self-reactive B cells present self antigen and respond normally to CD40-dependent T-cell signal but are defective in antigen-receptor-mediated functions
    • Eris JM, Basten A, Brink R, Doherty K, Kehry MR, Hodgkin PD: Anergic self-reactive B cells present self antigen and respond normally to CD40-dependent T-cell signal but are defective in antigen-receptor-mediated functions. Proc Natl Acad Sci USA 1994, 91:4392-4396.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4392-4396
    • Eris, J.M.1    Basten, A.2    Brink, R.3    Doherty, K.4    Kehry, M.R.5    Hodgkin, P.D.6
  • 27
    • 0028294575 scopus 로고
    • Hypercross-linking surface IgM or IgG receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti- CD40
    • Parry SL, Halbold J, Holman M, Klaus GGB: Hypercross-linking surface IgM or IgG receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40. J Immunol 1994, 152:2821-2829.
    • (1994) J Immunol , vol.152 , pp. 2821-2829
    • Parry, S.L.1    Halbold, J.2    Holman, M.3    Klaus, G.G.B.4
  • 28
    • 0024414103 scopus 로고
    • A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas
    • Stamenkovic I, Clark EA, Seed B: A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. EMBO J 1989, 8:1403-1410.
    • (1989) EMBO J , vol.8 , pp. 1403-1410
    • Stamenkovic, I.1    Clark, E.A.2    Seed, B.3
  • 29
    • 0030056358 scopus 로고    scopus 로고
    • CD40-CD40 ligand: A multifunctional receptor-ligand pair
    • Van Kooten C, Banchereau J: CD40-CD40 ligand: a multifunctional receptor-ligand pair. Adv Immunol 1996, 61:1-77.
    • (1996) Adv Immunol , vol.61 , pp. 1-77
    • Van Kooten, C.1    Banchereau, J.2
  • 30
    • 0026427043 scopus 로고
    • Growing human B lymphocytes in the CD40 system
    • Banchereau J, Rousset F: Growing human B lymphocytes in the CD40 system. Nature 1991, 353:678-679.
    • (1991) Nature , vol.353 , pp. 678-679
    • Banchereau, J.1    Rousset, F.2
  • 31
    • 0026563156 scopus 로고
    • Interleukin 10 and transforming growth factor β cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A
    • Defrance T, Vanbervliet B, Brière F, Durand I, Rousset F, Banchereau J: Interleukin 10 and transforming growth factor β cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A. J Exp Med 1992, 175:671-682.
    • (1992) J Exp Med , vol.175 , pp. 671-682
    • Defrance, T.1    Vanbervliet, B.2    Brière, F.3    Durand, I.4    Rousset, F.5    Banchereau, J.6
  • 32
    • 0026584291 scopus 로고
    • Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes
    • Rousset F, Garcia E, Defrance T, et al.: Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci USA 1992, 89:1890-1893.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1890-1893
    • Rousset, F.1    Garcia, E.2    Defrance, T.3
  • 33
    • 0028082477 scopus 로고
    • Human interleukin-10 induces naive surface immunoglobulin D+ (slgD+) B cells to secrete IgG1 and IgG3
    • Brière F, Servet-Delprat C, Bridon JM, Saint-Remy JM, Banchereau J: Human interleukin-10 induces naive surface immunoglobulin D+ (slgD+) B cells to secrete IgG1 and IgG3. J Exp Med 1994, 179:757-762.
    • (1994) J Exp Med , vol.179 , pp. 757-762
    • Brière, F.1    Servet-Delprat, C.2    Bridon, J.M.3    Saint-Remy, J.M.4    Banchereau, J.5
  • 34
    • 0027440245 scopus 로고
    • Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukemic B lymphocytes
    • Fluckiger AC, Garrone P, Durand I, Galzzi JP, Banchereau J: Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukemic B lymphocytes. J Exp Med 1993, 178:1473-1481.
    • (1993) J Exp Med , vol.178 , pp. 1473-1481
    • Fluckiger, A.C.1    Garrone, P.2    Durand, I.3    Galzzi, J.P.4    Banchereau, J.5
  • 35
    • 0030061131 scopus 로고    scopus 로고
    • CD40 and B cell antigen receptor dual triggering of resting B lymphocytes turns on a partial geminal center phenotype
    • Galibert L, Burdin N, de Saint-Vis F, et al.: CD40 and B cell antigen receptor dual triggering of resting B lymphocytes turns on a partial geminal center phenotype. J Exp Med 1996, 183:77-85.
    • (1996) J Exp Med , vol.183 , pp. 77-85
    • Galibert, L.1    Burdin, N.2    De Saint-Vis, F.3
  • 36
    • 0029876593 scopus 로고    scopus 로고
    • CD40-mediated signaling in B cells
    • Kehry MR: CD40-mediated signaling in B cells. J Immunol 1996, 156:2345-2348.
    • (1996) J Immunol , vol.156 , pp. 2345-2348
    • Kehry, M.R.1
  • 37
    • 0026478651 scopus 로고
    • Rescue from anti-lgM-induced programmed cell death by the B cell surface proteins CD20 and CD40
    • Valentine MA, Licciardi KA: Rescue from anti-lgM-induced programmed cell death by the B cell surface proteins CD20 and CD40. Eur J Immunol 1992, 22:3141-3148.
    • (1992) Eur J Immunol , vol.22 , pp. 3141-3148
    • Valentine, M.A.1    Licciardi, K.A.2
  • 38
    • 0027236043 scopus 로고
    • B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40
    • Tsubata T, Wu J, Honjo T: B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40. Nature 1993, 364:645-648.
    • (1993) Nature , vol.364 , pp. 645-648
    • Tsubata, T.1    Wu, J.2    Honjo, T.3
  • 41
    • 0029931056 scopus 로고    scopus 로고
    • Ligation of CD40 influences the function of human Ig secreting B cell hybridomas both positively and negatively
    • Bergman MC, Attrep JF, Grammer AC, Lipsky PE: Ligation of CD40 influences the function of human Ig secreting B cell hybridomas both positively and negatively. J Immunol 1996, 156:3118-3132.
    • (1996) J Immunol , vol.156 , pp. 3118-3132
    • Bergman, M.C.1    Attrep, J.F.2    Grammer, A.C.3    Lipsky, P.E.4
  • 42
    • 0030067795 scopus 로고    scopus 로고
    • A novel function of CD40: Induction of cell death in transformed cells
    • Hess S, Engelmann H: A novel function of CD40: Induction of cell death in transformed cells. J Exp Med 1996, 183:159-167.
    • (1996) J Exp Med , vol.183 , pp. 159-167
    • Hess, S.1    Engelmann, H.2
  • 43
    • 0027122957 scopus 로고
    • 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults
    • Centers for Disease Control and Prevention: 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. MMWR 1992, 41 (RR-17): 1-19.
    • (1992) MMWR , vol.41 , Issue.RR-17 , pp. 1-19
  • 44
    • 0028130412 scopus 로고
    • Spontaneous in vitro anti-human immunodeficiency virus type 1 antibody secretion by peripheral blood mononuclear cells is related to disease progression in zidovudine-treated adults
    • Conge AM, Reynes J, Atoui N, et al.: Spontaneous in vitro anti-human immunodeficiency virus type 1 antibody secretion by peripheral blood mononuclear cells is related to disease progression in zidovudine-treated adults. J Infect Dis 1994, 170:1376-1383.
    • (1994) J Infect Dis , vol.170 , pp. 1376-1383
    • Conge, A.M.1    Reynes, J.2    Atoui, N.3
  • 45
    • 0024408995 scopus 로고
    • Human lymphokine-activated killer cells suppress pokeweed mitogen-induced immunoglobulin synthesis
    • Suzuki U, Yamashita N, Maruyama M, Yoshikawa T, Yano S: Human lymphokine-activated killer cells suppress pokeweed mitogen-induced immunoglobulin synthesis. Clin Exp Immunol 1989, 78:406-411.
    • (1989) Clin Exp Immunol , vol.78 , pp. 406-411
    • Suzuki, U.1    Yamashita, N.2    Maruyama, M.3    Yoshikawa, T.4    Yano, S.5
  • 46
    • 0027160712 scopus 로고
    • Quantification of HIV-1 RNA in plasma using NASBA during HIV-1 primary infection
    • Van Gemen B, Kievits T, Schukkink R, et al.: Quantification of HIV-1 RNA in plasma using NASBA during HIV-1 primary infection. J Virol Methods 1993, 43:177-187.
    • (1993) J Virol Methods , vol.43 , pp. 177-187
    • Van Gemen, B.1    Kievits, T.2    Schukkink, R.3
  • 47
    • 0023233217 scopus 로고
    • Analysis of the antigen- and mitogen-induced differentiation of B lymphocytes from asymptomatic human immunodeficiency virus-seropositive male homosexuals
    • Teeuwsen VJP, Logtenberg T, Siebelink KHJ, et al.: Analysis of the antigen- and mitogen-induced differentiation of B lymphocytes from asymptomatic human immunodeficiency virus-seropositive male homosexuals. J Immunol 1987, 139:2929-2935.
    • (1987) J Immunol , vol.139 , pp. 2929-2935
    • Teeuwsen, V.J.P.1    Logtenberg, T.2    Siebelink, K.H.J.3
  • 48
    • 0026445919 scopus 로고
    • Human B lymphocytes: Phenotype, proliferation and differentiation
    • Banchereau J, Rousset F: Human B lymphocytes: phenotype, proliferation and differentiation. Adv Immunol 1992, 52:125-251.
    • (1992) Adv Immunol , vol.52 , pp. 125-251
    • Banchereau, J.1    Rousset, F.2
  • 49
    • 0027763586 scopus 로고
    • Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD 38
    • Howard M, Grimaldi JC, Bazan JF et al.: Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD 38. Science 1993, 262:1056-1059.
    • (1993) Science , vol.262 , pp. 1056-1059
    • Howard, M.1    Grimaldi, J.C.2    Bazan, J.F.3
  • 50
    • 85012474693 scopus 로고
    • The immunopathogenesis of human immunodeficiency virus infection
    • Pantaleo G, Graziosi C, Fauci AS: The immunopathogenesis of human immunodeficiency virus infection. N Engl J Med 1993, 328:327-335.
    • (1993) N Engl J Med , vol.328 , pp. 327-335
    • Pantaleo, G.1    Graziosi, C.2    Fauci, A.S.3
  • 51
    • 0002499409 scopus 로고    scopus 로고
    • Clinical spectrum of human immunodeficiency virus diseases
    • Edited by DeVita Jr VT, Hellman S, Rosenberg SA. New York: Eippincott-Raven Publishers
    • Saag MS: Clinical spectrum of human immunodeficiency virus diseases. In AIDS: Biology, Diagnosis, Treatment and Prevention, 4th Edition. Edited by DeVita Jr VT, Hellman S, Rosenberg SA. New York: Eippincott-Raven Publishers; 1997:203-213.
    • (1997) AIDS: Biology, Diagnosis, Treatment and Prevention, 4th Edition , pp. 203-213
    • Saag, M.S.1
  • 52
    • 0025069873 scopus 로고
    • The prognostic value of cellular and serological markers in infection with human immunodeficiency virus type 1
    • Fahey JL, Taylor JM, Detels R, et al.: The prognostic value of cellular and serological markers in infection with human immunodeficiency virus type 1. N Engl J Med 1990, 322:166-172.
    • (1990) N Engl J Med , vol.322 , pp. 166-172
    • Fahey, J.L.1    Taylor, J.M.2    Detels, R.3
  • 53
    • 0028000730 scopus 로고
    • Evaluation of proviral copy number and plasma RNA level as early indicators of progression in HIV-1 infection: Correlation with virological and immunological markers of disease
    • Verhofstede C, Reniers S, Van Wanzeele F, Plume J: Evaluation of proviral copy number and plasma RNA level as early indicators of progression in HIV-1 infection: correlation with virological and immunological markers of disease. AIDS 1994, 8:1421-1427.
    • (1994) AIDS , vol.8 , pp. 1421-1427
    • Verhofstede, C.1    Reniers, S.2    Van Wanzeele, F.3    Plume, J.4
  • 55
    • 0026688237 scopus 로고
    • The B-cell antigen receptor complex-associated of Ig-α and Ig-β with distinct cytoplasmic effectors
    • Clarck MR, Campbell KS, Kazlauskas A, et al.: The B-cell antigen receptor complex-associated of Ig-α and Ig-β with distinct cytoplasmic effectors. Science 1992, 258:123-126.
    • (1992) Science , vol.258 , pp. 123-126
    • Clarck, M.R.1    Campbell, K.S.2    Kazlauskas, A.3
  • 57
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle PA, Henkel T: Function and activation of NF-κB in the immune system. Annu Rev Immunol 1994, 12:141-179.
    • (1994) Annu Rev Immunol , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 58
    • 0028152658 scopus 로고
    • Cross-linking CD40 on B cells rapidly activates nuclear factor-κB
    • Berberich I, Shu GL, Clark EA: Cross-linking CD40 on B cells rapidly activates nuclear factor-κB. J Immunol 1994, 153:4357-4366.
    • (1994) J Immunol , vol.153 , pp. 4357-4366
    • Berberich, I.1    Shu, G.L.2    Clark, E.A.3
  • 59
    • 0028867899 scopus 로고
    • Immunosuppression by glycocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
    • Auphan N, Didonato JA, Rosette C, Helmberg A, Karin M: Immunosuppression by glycocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science 1995, 270:286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    Didonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 60
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids
    • Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS: Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids. Science 1995, 270:283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin, A.S.4
  • 61
    • 0028208710 scopus 로고
    • Defective protein tyrosine phosphorylation and altered levels of p59fyn and p56lck in CD4 T cells from HIV-1 infected patients
    • Cayota A, Vuillier F, Siciliano J, Dighiero G: Defective protein tyrosine phosphorylation and altered levels of p59fyn and p56lck in CD4 T cells from HIV-1 infected patients. Int Immunol 1994, 6:611-621.
    • (1994) Int Immunol , vol.6 , pp. 611-621
    • Cayota, A.1    Vuillier, F.2    Siciliano, J.3    Dighiero, G.4
  • 62
    • 0027199115 scopus 로고
    • Reactive oxygen intermediates activate NF-κB in a tyrosine kinase-dependent mechanism and in combination with vanadate activate the p56lck and p59fyn tyrosine kinases in human lymphocytes
    • Schieven GL, Kirihara JM, Myers DE, Ledbetter JA, Uckun FM: Reactive oxygen intermediates activate NF-κB in a tyrosine kinase-dependent mechanism and in combination with vanadate activate the p56lck and p59fyn tyrosine kinases in human lymphocytes. Blood 1993, 82:1212-1220.
    • (1993) Blood , vol.82 , pp. 1212-1220
    • Schieven, G.L.1    Kirihara, J.M.2    Myers, D.E.3    Ledbetter, J.A.4    Uckun, F.M.5
  • 63
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • Buttke TM, Sandstrom PA: Oxidative stress as a mediator of apoptosis. Immunol Today 1994, 15:7-10.
    • (1994) Immunol Today , vol.15 , pp. 7-10
    • Buttke, T.M.1    Sandstrom, P.A.2
  • 64
    • 0029953871 scopus 로고    scopus 로고
    • In vitro antioxidant treatment recovers proliferative responses of anergic CD4+ lymphocytes from human immunodeficiency virus-infected individuals
    • Cayota A, Vuillier F, Gonzalez G, Dighiero G: In vitro antioxidant treatment recovers proliferative responses of anergic CD4+ lymphocytes from human immunodeficiency virus-infected individuals. Blood 1996, 87:4746-4753.
    • (1996) Blood , vol.87 , pp. 4746-4753
    • Cayota, A.1    Vuillier, F.2    Gonzalez, G.3    Dighiero, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.