Neurochemical alterations in the cerebellum of a murine model of Niemann-Pick type C disease

Brain Research

Volumn 799, Issue 2, 1998, Pages 250-256

  Yadid, Gal ^a   Sotnik Barkai, Iris ^a   Tornatore, Carlo ^b   Baker Cairns, Belinda ^b   Harvey White, Judith ^b   Pentchev, Peter G ^b   Goldin, Ehud ^b  

^a BAR ILAN UNIVERSITY   (Israel)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

Cerebellum; Glycine; L DOPA; Niemann Pick type C disease; Serotonin; Tyrosine hydroxylase

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; LEVODOPA; TYROSINE 3 MONOOXYGENASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; CEREBELLUM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DEMENTIA; DYSTONIA; FEMALE; MALE; METABOLIC DISORDER; MOUSE; NEUROCHEMISTRY; NEUROFIBRILLARY TANGLE; NIEMANN PICK DISEASE; NONHUMAN; PRIORITY JOURNAL; PROGRESSIVE SUPRANUCLEAR PALSY; SEIZURE; VISUAL DISORDER;

AMINO ACIDS; ANIMALS; BIOGENIC MONOAMINES; BRAIN; CEREBELLUM; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED BALB C; NEUROTRANSMITTER AGENTS; NIEMANN-PICK DISEASES; REFERENCE VALUES; TISSUE DISTRIBUTION; TYROSINE 3-MONOOXYGENASE;

EID: 0032551693     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00449-1     Document Type: Article

References (33)

1. A.M. Batchelor, D.J. Madge, J. Garthwaite, Synaptic activation of metabotropic glutamate receptors in the parallel fiber-Purkinje cell pathway in rat cerebellar slices, Neuroscience 63 (1994) 911-915.
2. B.A. Bidlingmeyer, S.A. Cohen, T.L.J. Tatvin, Rapid analysis of amino acids using pre-column derivatization, Chromatography 336 (1984) 93-104.
3. E.J. Blanchette-Mackie, N.K. Dwyer, L.M. Amende, H.S. Kruth, J.D. Butler, J. Sokol, M.E. Comly, M.T. Vanier, J.T. August, R.O. Brady, P.G. Pentchev, Type-C Niemann-Pick disease: Low density lipoprotein uptake is associated with premature cholesterol accumulation in the Golgi complex and excessive cholesterol storage in lysosomes, Proc. Natl. Acad. Sci. USA 85 (1988) 8022-8026.
4. K.M. Boje, G. Wong, P. Skolnick, Desensitization of the NMDA receptor complex by glycinergic ligands in cerebellar granule cell cultures, Brain Res. 603 (1993) 207-214.
5. E.D. Carstea, J.A. Morris, K.G. Coleman, S.K. Loftus, D. Zhang, C. Cummings, J. Gu, M.A. Rosenfeld, W.J. Pavan, D.B. Krizman, J. Nagle, M.H. Polymeropoulos, S.L. Sturley, Y.A. Ioannou, M.E. Higgins, M. Comly, A. Cooney, A. Brown, C.R. Kaneski, E.J. Blanchette-Mackie, N.K. Dwyer, E.B. Neufeld, T.Y. Chang, L. Liscum, D.A. Tagle et al., Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis, Science 277 (1997) 228-231.
6. S. Chen, D.E. Hillman, Co-localization of neurotransmitters in the deep cerebellar nuclei, J. Neurocytol. 22 (1993) 81-91.
7. S. Dieudonne, Glycinergic synaptic currents in Golgi cells of the rat cerebellum, Proc. Natl. Acad. Sci. USA 92 (1995) 1441-1458.
8. Y. Higashi, S. Murayama, P.G. Penchev, K. Suzuki, Cerebellar degeneration in the Niemann-Pick type C mouse, Acta Neuropathol. 85 (1993) 175-184.
9. J.J. Higgins, M.C. Patterson, J.M. Dambrosia, A.T. Pikus, P.G. Pentchev, S. Sato, R.O. Brady, N.W. Barton, A clinical staging classification for type C Niemann-Pick disease, Neurology 42 (1992) 2286-2290.
10. C.B. Jaeger, G. Teitelman, T.H. Joh, V.R. Albert, D.H. Park, D.J. Reis, Some neurons of the rat central nervous system contain aromatic L-amino acid decarboxylase but not monoamines, Science 219 (1983) 1233-1235.
11. M. Kaneda, M. Farrant, S.G. Cull-Candy, Whole-cell and single-channel currents activated by GABA and glycine in granule cells of the rat cerebellum, J. Physiol. (Lond.) 485 (1995) 419-435.
12. K. Kitahama, N. Mons, H. Okamura, M. Jouvet, M. Geffard, Endogenous L-DOPA, its immunoreactivity in neurons of midbrain and its projection field in the cat, Neurosci. Lett. 95 (1988) 47-52.
13. K. Komori, T. Fujii, I. Nagatsu, Do some tyrosine hydroxylase immunoreactive neurons in the human ventrolateral arcuate nucleus and globus pallidus produce only L-DOPA?, Neurosci. Lett. 133 (1991) 203-206.
14. H. Komuro, P. Rakic, Modulation of neuronal migration by NMDA receptors, Science 260 (1993) 95-97.
15. L. Liscum, J.R. Faust, Low-density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick fibroblasts, J. Biol. Chem. 262 (1987) 17002-17008.
16. L. Liscum, R.M. Ruggiero, J.R. Faust, The intracellular transport of low-density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts, J. Cell Biol. 108 (1989) 1625-1636.
17. S.K. Loftus, J.A. Morris, E. Carstea, J. Gu, C. Cummings, A. Brown, J. Ellison, K. Ohno, M.A. Rosenfeld, D.A. Tagle, P.G. Pentchev, W.J. Pavan, Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene, Science 277 (1997) 232-235.
18. J.M. Luque, N. Nelson, J.G. Richards, Cellular expression of glycine transporter 2 messenger RNA exclusively in rat midbrain and spinal cord, Neuroscience 64 (1995) 525-535.
19. M.C. Miquel, H.K. Kia, C. Boni, E. Doucet, G. Daval, L. Matthiessen, M. Hamon, D. Verge, Postnatal development and localization of 5-HT1A receptor mRNA in rat forebrain and cerebellum, Dev. Brain Res. 80 (1994) 149-157.
20. 2+ dependent and tetrodotoxin-sensitive release of endogenous glutamate from rat striatal slices, Brain Res. 617 (1993) 167-170.
21. Y. Misu, H. Ueda, Y. Goshima, Neurotransmitter-like action of L-DOPA, Adv. Pharmacol. 32 (1995) 427-459.
22. H. Mitoma, T. Kobayashi, S.Y. Song, S. Konishi, Enhancement by serotonin of GABA-mediated inhibitory synaptic currents in rat cerebellar Purkinje cells, Neurosci. Lett. 173 (1994) 127-130.
23. J.G. Netzeband, L.B. Weathers, H.K. Strahlendorf, J.C. Strahlendorf, Serotonin depresses excitatory amino acid-induced excitation of the cerebellar Purkinje cells in the rat in vivo, Brain Res. 608 (1993) 145-149.
24. P.G. Pentchev, A.D. Booth, H.S. Kruth, H. Weintroub, J. Stivers, R.O. Brady, A genetic storage disorder in Balb/C mice with a metabolic block in esterification of exogenous cholesterol, J. Biol. Chem. 259 (1984) 5784-5791.
25. P.G. Penchev, M.E. Comly, H.S. Kruth, T. Tokoro, J.D. Butler, J. Sokol, M. Filling-Katz, J.M. Quirk, D.C. Marshall, S. Patel, M.T. Vanier, R.O. Brady, Group C Niemann-Pick disease: faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblasts, FASEB J. 1 (1987) 40-45.
26. P.G. Pentchev, A.E. Gal, A.D. Booth, F. Omodeo-Sale, J. Fouks, B.A. Neumeyer, J.M. Quijk, D. Dawson, R.O. Brady, A lysosomal storage disorder in mice characterized by dual deficiency of sphingomyelinase and glucocerebrosidase, Biochim. Biophys. Acta 619 (1980) 669-679.
27. J. Sokol, E.J. Blanchette-Mackie, H.S. Kruth, N.K. Dwyer, L.M. Amende, J.D. Butler, E. Robinson, S. Patel, R.O. Brady, M.E. Comly, M.T. Vanier, P.G. Pentchev, Type C Niemann-Pick disease. Lysosomal accumulation and defective intracellular mobilization of low-density lipoprotein cholesterol, J. Biol. Chem. 263 (1988) 123-128.
28. K. Suzuki, C.C. Parker, P.G. Pentchev, D. Katz, B. Ghetti, A.N. D'Agostino, E.D. Carstea, Neurofibrillary tangles in Niemann-Pick disease type C, Acta Neuropathol. (Berl.) 89 (1995) 227-238.
29. C. Tornatore, B. Baker-Cairns, G. Yadid, R. Hamilton, K. Meyers, W. Atwood, A. Cummins, V. Tanner, E. Major, Expression of tyrosine hydroxylase in an immortalized human fetal astrocyte cell line; in vitro characterization and engraftment into the rodent striaturn, Cell Transplant. 5 (1996) 145-163.
30. G. Yadid, K. Pacak, I.J. Kopin, D.S. Goldstein, Endogenous serotonin stimulates striatal dopamine release in conscious rats, J. Pharmacol. Exp. Ther. 270 (1994) 1158-1165.
31. A. Zangen, D. Overstreet, G. Yadid, High serotonin and 5-hydroxy-indoleacetic acid levels in limbic brain regions in a rat model of depression: Normalization by chronic antidepressant treatment, J. Neurochem. 69 (1997) 2477-2483.
32. M.C. Austin, M. Schultzberg, L.C. Abbott, P. Montpied, J.R. Evers, S.M. Paul, J.N. Crawley, Expression of tyrosine hydroxylase in cerebellar Purkinje neurons of the mutant tottering and leaner mouse, Mol. Brain Res. 15 (1992) 227-240.
33. E.J. Hess, M.C. Wilson, Tottering and leaner mutants perturb transient developmental expression of tyrosine hydroxylase in embryologically distinct Purkinje cells, Neuron 6 (1991) 123-132.