Calculated and experimental low-energy conformations of cyclic urea HIV protease inhibitors

Journal of the American Chemical Society

Volumn 120, Issue 19, 1998, Pages 4570-4581

  Hodge, C Nicholas ^a   Lam, Patrick Y S ^a   Eyermann, Charles J ^a   Jadhav, Prabhakar K ^a   Ru, Y ^a   Fernandez, Christina H ^a   De Lucca, George V ^a   Chang, Chong Hwan ^a   Kaltenbach III, Robert F ^a   Holler, Edward R ^a   Woerner, Francis ^a   Daneker, Wayne F ^a   Emmett, George ^a   Calabrese, Joseph C ^a   Aldrich, Paul E ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE INHIBITOR; UREA DERIVATIVE;

AQUEOUS SOLUTION; ARTICLE; CALCULATION; CLINICAL PROTOCOL; CRYSTAL STRUCTURE; DRUG CONFORMATION; LIGAND BINDING; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RECEPTOR AFFINITY; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 0032550655     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja972357h     Document Type: Article

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