A search for single substitutions that eliminate enzymatic function in a bacterial ribonuclease

Biochemistry

Volumn 37, Issue 20, 1998, Pages 7157-7166

  Axe, Douglas D ^a   Foster, Nicholas W ^a   Fersht, Alan R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; RIBONUCLEASE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INACTIVATION; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; CATALYSIS; DNA MUTATIONAL ANALYSIS; ENZYME ACTIVATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POLYMERASE CHAIN REACTION; PROTEIN ENGINEERING; RIBONUCLEASES;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0032546542     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9804028     Document Type: Article

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