Transient affinity tags based on the Dde protection/deprotection strategy: Synthesis and application of 2-biotinyl- and 2-hexanoyldimedone

Tetrahedron Letters

Volumn 38, Issue 30, 1997, Pages 5391-5394

  Kellam, Barrie ^a   Chan, Weng C ^a   Chhabra, Siri Ram ^a   Bycroft, Barrie W ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTIN; HEXANOIC ACID; PEPTIDE; REAGENT;

ACYLATION; AFFINITY CHROMATOGRAPHY; ARTICLE; CHEMICAL REACTION; COLUMN CHROMATOGRAPHY; PURIFICATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SYNTHESIS; TECHNIQUE;

EID: 0030877831     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01180-5     Document Type: Article

References (16)

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13. 4S (M+H), 367.169154.
14. 3 (M+H), 239.
15. 2O, linear gradient 10% to 50% B in 20 min at 1.2 ml/min and post column eluent detection at 220 nm.
16. 18 Sep-Pak cartridge. Evaporation of the desalted solution gave after ether trituration the pure peptide as a white amorphous solid (2 mg).