Analysis of glutamines in catalysis in Cephalosporium acremonium isopenicillin N synthase by site-directed mutagenesis

Biochemical and Biophysical Research Communications

Volumn 252, Issue 2, 1998, Pages 472-475

  Loke, Paxton ^a   Sim, Tiow Suan ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Cephalosporium acremonium; Glutamine; Isopenicillin N synthase; Site directed mutagenesis

Indexed keywords

AMINO ACID; BETA LACTAM ANTIBIOTIC; GLUTAMINE; ISOENZYME; ISOPENICILLIN N; ISOPENICILLIN N SYNTHETASE; LIGAND;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CEPHALOSPORIUM ACREMONIUM; CRYSTAL STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ASPERGILLUS NIDULANS; CEPHALOSPORIUM ACREMONIUM;

EID: 0032544925     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1998.9663     Document Type: Article

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