Possible role of telomerase activation in the cancer predisposition of patients with hereditary nonpolyposis colorectal cancers

Journal of the National Cancer Institute

Volumn 90, Issue 4, 1998, Pages 316-321

  Cheng, Ann Joy ^a   Tang, Reiping ^c   Wang, Jeng Yi ^c   See, Lai Chu ^b   Wang, Tzu Chien V ^a,b  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE;

ARTICLE; AUTOSOMAL DOMINANT DISORDER; BASE MISPAIRING; CANCER SUSCEPTIBILITY; CARCINOGENESIS; COLON CANCER; ENZYME ACTIVATION; ENZYME ACTIVITY; GERM LINE; HUMAN; HUMAN TISSUE; RECEPTOR UPREGULATION; TELOMERE;

EID: 0032542525     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/90.4.316     Document Type: Article

References (29)

1. Lynch HT, Smyrk TC, Watson P, Lanspa SJ, Lynch JF, Lynch PM, et al. Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review. Gastroenterology 1993; 104:1535-49.
2. Lynch HT, Smyrk T, Lynch JF. Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch syndrome). Int J Cancer 1996;69:38-43.
3. Modrich P, Lahue R. Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu Rev Biochem 1996;65:101-33.
4. Kolodner R. Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev 1996;10:1433-42.
5. Leach FS, Nicolaides NC, Papadopoulos N, Liu B, Jen J, Parsons R, et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993;75:1215-25.
6. Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996;87:159-70.
7. Liu B, Parsons RE, Hamilton SR, Petersen GM, Lynch HT, Watson P, et al. hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds. Cancer Res 1994;54:4590-4.
8. Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 1965;37:614-36.
9. Harley CB, Kim NW, Prowse KR, Weinrich SL, Hirsch, KS, West MD, et al. Telomerase, cell immortality and cancer. Cold Spring Harb Symp Quant Biol 1994;59:307-15.
10. Blackburn EH. Telomerases. Annu Rev Biochem 1992;61:113-29.
11. Harley CB. Telomere loss: mitotic clock or genetic time bomb? Mutat Res 1991;256:271-82.
12. Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW, Harley CB, et al. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 1992;11:1921-9.
13. Counter CM, Hirte HW, Bacchetti S, Harley CB. Telomerase activity in human ovarian carcinoma. Proc Natl Acad Sci U S A 1994;91:2900-4.
14. Shay JW, Bacchetti S. A survey of telomerase activity in human cancer. Eur J Cancer 1997;33:787-91.
15. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994;266:2011-5.
16. Hermanek P, Sobin LH, editors. TNM Classification of malignant tumors. 4th ed. Berlin: Springer-Verlag, 1987:47-9.
17. Morson BC, Sobin LH. Histological typing of intestinal tumours. Geneva: World Health Organization, 1976. Technical report No. 15.
18. Bertario L, Aste H, Arrigoni A, Fracasso P, Rossini FP, Rossetti C, et al. Clinical aspects and management of hereditary non-polyposis colorectal cancer (HNPCC). Tumor 1996;82:117-21.
19. Cheng AJ, Liao SK, Chow SE, Chen JK, Wang TC. Differential inhibition of telomerase activity during induction of differentiation in hematopoietic, melanoma and glioma cells in culture. Biochem Biophys Res Commun 1997;237:438-44.
20. Rothman KJ. Modern epidemiology. Boston: Little, Brown, 1986.
21. Rosner B. Fundamentals of Biostatistics. 4th ed. Boston: Duxbury, 1995.
22. Patchett SE, Alstead EM. Saunders BP, Hodgson SV, Farthing MJ. Regional proliferative patterns in the colon of patients at risk for hereditary nonpolyposis colorectal cancer. Dis Colon Rectum 1997;40:168-71.
23. Yasumoto S, Kunimura C, Kikuchi K, Tahara H, Ohji H, Yamamoto H, et al. Telomerase activity in normal human epithelial cells. Oncogene 1996; 13:433-9.
24. Li ZH, Salovaara R, Aaltonen LA, Shibata D. Telomerase activity is commonly detected in hereditary nonpolyposis colorectal cancers. Am J Pathol 1996;148:1075-9.
25. Chadeneau C, Hay K, Hirte HW, Gallinger S, Bacchetti S. Telomerase activity associated with acquistition of malignancy in human colorectal cancer. Cancer Res 1995;55:2533-6.
26. Hiyama K, Hirai Y, Kyoizumi S, Akiyama M, Hiyama E, Piatyszek MA, et al. Activation of telomerase in human lymphocytes and hematopoietic progenitor cells. J Immunol 1995;155:3711-5.
27. Herle-Bachor C, Boukamp P. Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived skin keratinocytes. Proc Natl Acad Sci U S A 1996;93:6476-81.
28. Kyo S, Takakura M, Kohama T, Inoue M. Telomerase activity in human endometrium. Cancer Res 1997;57:610-4.
29. Parsons R, Li GM, Longley M, Modrich P, Liu B, Berk T, et al. Mismatch repair deficiency in phenotypically normal human cells. Science 1995;268: 738-40.