The effects of diminishing albumin binding to some endothelin receptor antagonists

Life Sciences

Volumn 63, Issue 21, 1998, Pages 1905-1912

  Szczepankiewicz, Bruce G ^a   Bal, Radhika B ^a   Von Geldern, Thomas W ^a   Wu Wong, Jinshyun R ^a   Chiou, William J ^a   Dixon, Douglas B ^a   Opgenorth, Terry J ^a   Hoffman, Daniel J ^a   Borre, Anthony J ^a   Marsh, Kennan C ^a   Nguyen, Bach N ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

A 200379; A 127722; A 207508; A 212194; Albumin binding; Endothelin; Endothelin receptor; Endothelin A receptor antagonist; Plasma protein binding

Indexed keywords

4 (4 METHOXYPHENYL) 2 (3,4 METHYLENEDIOXYPHENYL) 4 OXO 3 (3,4,5 TRIMETHOXYBENZYL) 2 BUTENOIC ACID; ALBUMIN; ATRASENTAN; ENDOTHELIN A RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; DRUG POTENCY; DRUG PROTEIN BINDING; ENDOTHELIUM CELL; MALE; MOLECULAR CLONING; NONHUMAN; PROTEIN BINDING; PROTEIN FOLDING; RAT; RECEPTOR BINDING;

ANIMALS; CHO CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; ENDOTHELIN-1; ENDOTHELIN-3; HUMANS; MALE; PROTEIN BINDING; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; SERUM ALBUMIN; STEREOISOMERISM;

ANIMALIA;

EID: 0032538495     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(98)00466-4     Document Type: Article

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