Purinergic Ca2+ signaling in myenteric neurons via P2 purinoceptors

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 272, Issue 3 35-3, 1997, Pages

  Christofi, F L ^a   Guan, Z ^a   Wood, J D ^a   Baidan, L V ^a   Stokes, B T ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

adenosine 5' triphosphate; calbindin immunoreactivity; enteric neurons; fura 2; intracellular free calcium; microfluorimetry; nucleotides

Indexed keywords

2 CHLORO 6 N CYCLOPENTYLADENOSINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE DERIVATIVE; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CALBINDIN; CALCIUM ION; CIBACRON BLUE F3GA; FURA 2; PURINE P2 RECEPTOR; PYRIDOXAL 5 PHOSPHATE; SURAMIN; TETRODOTOXIN; CALCIUM;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; GUINEA PIG; MICROFLUOROMETRY; MYENTERIC PLEXUS; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMALL INTESTINE; SYNAPTIC TRANSMISSION; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; INTESTINE INNERVATION; METABOLISM; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION;

ADENOSINE; ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; CELLS, CULTURED; ENTERIC NERVOUS SYSTEM; GUINEA PIGS; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SURAMIN; TETRODOTOXIN;

EID: 0031087852     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1997.272.3.g463     Document Type: Article

References (40)

1. Baidan, L. V., M. A. Baidan, and J. D. Wood. Patch clamp study of effects of ATP and 2-chloroadenosine on whole-cell currents in cultured myenteric neurons (Abstract). Drug Dev. Res. 31: 244, 1994.
2. Barajas-Lopez, C., M. Barrientos, and R. Espinosa-Luna. Suramin increases the efficacy of ATP to activate an inward current in myenteric neurons from guinea-pig ileum. Eur. J. Pharmacol. 250: 141-145, 1993.
3. 2y- purinoceptors of the guinea-pig submucosal neurons (Abstract). J. Neurosci. 22: E86, 1996.
4. Barajas-Lopez, C., R. Espinosa-Luna, and V. Gerzanich. ATP closes a potassium and opens a cationic conductance through different receptors in neurons of guinea pig submucous plexus. J. Pharmacol. Exp. Ther. 268: 1396-1402, 1994.
5. Blakely, A. G. H., J. E. Brockbank, S. S. Kelly, and S. A. Petersen. Effects of suramin on the concentration-response relationship of α,β-methylene ATP on the mouse vas deferens. J. Auton. Pharmacol. 11: 45-49, 1991.
6. Cherubini, E., and R. A. North. Inhibition of calcium spikes and transmitter release by gamma-aminobutyric acid in the guinea-pig myenteric plexus. Br. J. Pharmacol. 82: 101-105, 1984.
7. i) in myenteric multipolar neurons of the guinea-pig small bowel (Abstract). Gastroenterology 108: A921, 1995.
8. 28 immunoreactive neurons in myenteric ganglia. Brain Res. 725: 241-246, 1996.
9. Christofi, F. L., M. Hanani, N. Maudlej, and J. D. Wood. Enteric glial cells are major contributors to formation of cyclic AMP in myenteric plexus cultures from adult guinea-pig small intestine. Neurosci. Lett. 159: 107-110, 1993.
10. 1 receptors exist on myenteric AH/Dogiel type II neurons of the small intestine (Abstract). Neuroscience 18: 998, 1992.
11. Christofi, F. L., and J. D. Wood. Effects of PACAP on morphologically identified myenteric neurons in guinea pig small bowel. Am. J. Physiol. 264 (Gastrointest. Liver Physiol 27): G414-G421, 1993.
12. 1 purinoceptors on myenteric neurons of guinea-pig small bowel. Br. J. Pharmacol. 113: 703-710, 1994.
13. Crist, J. R., X. D. He, and R. K. Goyal. Both ATP and the peptide VIP are inhibitory neurotransmitters in guinea-pig ileum circular muscle. J. Physiol. (Lond.) 447: 119-131, 1992.
14. Evans, R. J., V. Derkach, and A. Surprenant. ATP mediates fast synaptic transmission in mammalian neurons. Nature 357: 503-505, 1992.
15. Furness, J. B., J. C. Bornstein, and D. C. Trussell. Shapes of nerve cells in the myenteric plexus of the guinea-pig small intestine revealed by the intracellular injection of dye. Cell Tissue Res. 254: 561-571, 1988.
16. Furness, J. B., D. C. Trussell, S. Pompolo, J. C. Bornstein, and T. K. Smith. Calbindin neurons of the guinea-pig small intestine: quantitative analysis of their numbers and projections. Cell Tissue Res. 260: 261-272, 1990.
17. Furness, J. B., H. M. Young, S. Pompolo, J. C. Bornstein, W. A. A. Kunze, and K. McConalogue. Plurichemical transmission and chemical coding of neurons in the digestive tract. Gastroenterology 108: 554-563, 1995.
18. Grafe, P., C. J. Mayer, and J. D. Wood. Synaptic modulation of calcium-dependent potassium conductance in myenteric neurons in the guinea-pig. J. Physiol. (Lond.) 305: 235-248, 1980.
19. Grynkiewicz, G., M. Poenie, and R. Y. Tsien. A new generation of Ca indicators with greatly improved fluorescence properties. J. Biol. Chem. 260: 3440-3450, 1985.
20. Hanani, M., Y. Xia, and J. D. Wood. Myenteric ganglia from the adult guinea-pig small intestine in tissue culture. Neurogastroenterol. Motil. 6: 103-118, 1994.
21. Hirst, G. D. S., M. E. Holman, and I. Spence. Two types of neurones in the myenteric plexus of duodenum in the guinea-pig. J. Physiol. (Lond.) 236: 303-326, 1974.
22. 2 purinoceptor agonists and purinergic nerve stimulation in the guinea-pig urinary bladder and taenia coli. Br. J. Pharmacol. 99: 617-621, 1990.
23. Iyer, V., J. C. Bornstein, M. Costa, J. B. Furness, Y. Takahashi, and T. Iwanaga. Electrophysiology of guinea-pig myenteric neurons correlated with immunoreactivity for calcium binding proteins. J. Auton. Nerv. Syst. 22: 141-150, 1988.
24. Jessen, K. R., M. J. Saffrey, and G. Burnstock. The enteric nervous system in tissue culture. I. Cell types and their interactions in explants of the myenteric and submucous plexuses from the guinea-pig, rabbit and rat. Brain Res. 262: 17-35, 1983.
25. Katayama, Y., and K. Morita. Adenosine 5′-triphosphate modulates membrane potassium conductance in guinea-pig myenteric neurones. J. Physiol. (Lond.) 408: 373-390, 1989.
26. 2x purinoceptors be classified pharmacologically? Trends Physiol. Sci. 16: 168-174, 1995.
27. 2x)-mediated fast excitatory postsynaptic potentials in myenteric neurons of guinea-pig: distribution and presynaptic regulation (Abstract). Gastroenterology 751: 1996.
28. Lepard, Q., R. A. Altschuld, and B. T. Stokes. Quantitation of intracellular free calcium in single adult cardiomyocytes by fura-2 fluorescence microscopy: calibration of fura-2 ratios. Biochem. Biophys. Res. Commun. 147: 120-126, 1987.
29. Li, C. W., A. Azzi, and K.-P. Huang. Effects of suramin, an anti-human immunodeficiency virus reverse transcriptase agent, on protein kinase C. J. Biol. Chem. 265: 5424-5428, 1990.
30. Mahoney, J. D., D. F. Donnelly, and G. G. Haddad. Adenosine-induced inhibition of vagal motoneuron excitability: receptor subtype and mechanisms. Am. J. Physiol. 264 (Gastrointest. Liver Physiol. 27): G124-G132, 1993.
31. Mihara, S. Intracellular recordings from neurones of the submucous plexus. Progr. Neurobiol. 40: 529-572, 1993.
32. Mihara, S., K. Hirai, Y. Katayama, and S. Nishi. Mechanisms underlying intracellular signal transduction of the slow IPSP in submucous neurones of the guinea-pig caecum. J. Physiol. (Lond.) 436: 621-641, 1991.
33. Niel, J. P., R. A. R. Bywater, and G. S. Taylor. Apamin-resistant post-stimulus hyperpolarization in the circular muscle of the guinea-pig ileum. J. Auton. Nerv. Syst. 9: 565-569, 1983.
34. Nishi, S., and R. A. North. Intracellular recording from the myenteric plexus of the guinea-pig ileum. J. Physiol. (Lond.) 231: 471-491, 1973.
35. North, R. A., and T. Tokimasa. Persistent calcium-sensitive potassium current and the resting properties of guinea-pig myenteric neurones. J. Physiol. (Lond.) 386: 333-353, 1987.
36. Palmer, J. M., J. D. Wood, and D. H. Zafirov. Purinergic inhibition in the small intestine myenteric plexus of the guinea-pig. J. Physiol. (Lond.) 387: 357-369, 1987.
37. Pennefather, P., B. Rancaster, P. R. Adams, and R. A. Nicoll. Two distinct Ca-dependent K currents in bullfrog sympathetic ganglion cells. Proc. Natl. Acad. Sci. USA 82: 3040-3044, 1985.
38. Wood, J. D. Electrical and synaptic behavior of enteric neurons. In: Handbook of Physiology. The Gastrointestinal System. Motility and Circulation. Bethesda, MD: Am. Physiol. Soc., 1989, sect. 6, vol. 1, pt. 1, chapt. 14, p. 465-517.
39. Xia, Y., L. V. Baidan, R. H. Fertel, and J. D. Wood. Determination of levels of cyclic AMP in the myenteric plexus of guinea-pig small intestine. Eur. J. Pharmacol. 206: 231-236, 1991.
40. Young, H. M., J. B. Furness, P. Sewell, E. F. Burcher, and C. J. Kandiah. Total numbers of neurons in myenteric ganglia of the guinea-pig small intestine. Cell Tissue Res. 272: 197-200, 1994.