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Volumn 92, Issue 10, 1998, Pages 3848-3856

The C-terminus of c-Abl is required for proliferation and viability signaling in a c-Abl/erythropoietin receptor fusion protein

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN RECEPTOR; HYBRID PROTEIN; PROTEIN TYROSINE KINASE;

EID: 0032533940     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.10.3848.422k44_3848_3856     Document Type: Article
Times cited : (7)

References (55)
  • 3
  • 4
    • 0021811764 scopus 로고
    • Structural organization of the bcr gene and its role in the Ph′ translocation
    • Heisterkamp N, Stam K, Groffen J, de Klein A, Grosveld G: Structural organization of the bcr gene and its role in the Ph′ translocation. Nature 315:758, 1985
    • (1985) Nature , vol.315 , pp. 758
    • Heisterkamp, N.1    Stam, K.2    Groffen, J.3    De Klein, A.4    Grosveld, G.5
  • 5
    • 0023697548 scopus 로고
    • The first BCR gene intron contains breakpoints in Philadelphia chromosome positive leukemia
    • Heisterkamp N, Knoppel E, Groffen J: The first BCR gene intron contains breakpoints in Philadelphia chromosome positive leukemia. Nucleic Acids Res 16:10069, 1988
    • (1988) Nucleic Acids Res , vol.16 , pp. 10069
    • Heisterkamp, N.1    Knoppel, E.2    Groffen, J.3
  • 6
    • 0021802841 scopus 로고
    • Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
    • Shtivelman E, Lifshitz B, Gale RP, Canaani E: Fused transcript of abl and bcr genes in chronic myelogenous leukaemia. Nature 315:550, 1985
    • (1985) Nature , vol.315 , pp. 550
    • Shtivelman, E.1    Lifshitz, B.2    Gale, R.P.3    Canaani, E.4
  • 7
  • 8
    • 0028084328 scopus 로고
    • The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity
    • erratum 124:865, 1994
    • Van Etten RA, Jackson PK, Baltimore D, Sanders MC, Matsudaira PT, Janmey PA: The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity. J Cell Biol 124:325, 1994 (erratum 124:865, 1994)
    • (1994) J Cell Biol , vol.124 , pp. 325
    • Van Etten, R.A.1    Jackson, P.K.2    Baltimore, D.3    Sanders, M.C.4    Matsudaira, P.T.5    Janmey, P.A.6
  • 9
    • 0025924674 scopus 로고
    • Activation of tyrosinase kinase and microfilament-bindmg functions of c-abl by bcr sequences in bcr/abl fusion proteins
    • McWhirter JR, Wang JY: Activation of tyrosinase kinase and microfilament-bindmg functions of c-abl by bcr sequences in bcr/abl fusion proteins. Mol Cell Biol 11:1553, 1991
    • (1991) Mol Cell Biol , vol.11 , pp. 1553
    • McWhirter, J.R.1    Wang, J.Y.2
  • 10
    • 0025348013 scopus 로고
    • Tyrosine kinase activity and transformation potency of bcr-abl oncogene products
    • Lugo TG, Pendergast AM, Muller AJ, Witte ON: Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. Science 247:1079, 1990
    • (1990) Science , vol.247 , pp. 1079
    • Lugo, T.G.1    Pendergast, A.M.2    Muller, A.J.3    Witte, O.N.4
  • 12
    • 0027422977 scopus 로고
    • A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins
    • McWhirter JR, Galasso DL, Wang JY: A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins. Mol Cell Biol 13:7587, 1993
    • (1993) Mol Cell Biol , vol.13 , pp. 7587
    • McWhirter, J.R.1    Galasso, D.L.2    Wang, J.Y.3
  • 13
    • 0030886766 scopus 로고    scopus 로고
    • A chimeric receptor/oncogene that can be regulated by a ligand in vitro and in vivo
    • Okuda K, D'Andrea A, Etten RA, Griffin JD: A chimeric receptor/oncogene that can be regulated by a ligand in vitro and in vivo. J Clin Invest 100:1708, 1997
    • (1997) J Clin Invest , vol.100 , pp. 1708
    • Okuda, K.1    D'Andrea, A.2    Etten, R.A.3    Griffin, J.D.4
  • 14
    • 0028332086 scopus 로고
    • Activation and inhibition of erythropoietin receptor function: Role of receptor dimerization
    • Watowich SS, Hilton DJ, Lodish HF: Activation and inhibition of erythropoietin receptor function: Role of receptor dimerization. Mol Cell Biol 14:3535, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 3535
    • Watowich, S.S.1    Hilton, D.J.2    Lodish, H.F.3
  • 15
    • 12044256844 scopus 로고
    • Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene
    • Andoniou CE, Thien CB, Langdon WY: Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene. EMBO J 13:4515, 1994
    • (1994) EMBO J , vol.13 , pp. 4515
    • Andoniou, C.E.1    Thien, C.B.2    Langdon, W.Y.3
  • 16
    • 0027939947 scopus 로고
    • She phosphorylation in myeloid cells is regulated by GM-CSF, IL-3, and Steel factor, and is constitutively increased by p210BCR/ABL
    • Matsuguchi I, Salgia R, Hallek M, Eder M, Druker B, Ernst T, Griffin JD: She phosphorylation in myeloid cells is regulated by GM-CSF, IL-3, and Steel factor, and is constitutively increased by p210BCR/ABL. J Biol Chem 269:5016, 1994
    • (1994) J Biol Chem , vol.269 , pp. 5016
    • Matsuguchi, I.1    Salgia, R.2    Hallek, M.3    Eder, M.4    Druker, B.5    Ernst, T.6    Griffin, J.D.7
  • 17
    • 0029669975 scopus 로고    scopus 로고
    • The proto-oncogene product p120(cbl) and the adaptor proteins crkl and c-crk link c-abl, p190(bcr/ abl) and p210(bcr/abl) to the phosphatidylinositol-3′ kinase pathway
    • Sattler M, Salgia R, Okuda K, Uemura N, Durstin MA, Pisick E, Xu G, Li JL, Prasad KV, Griffin JD: The proto-oncogene product p120(cbl) and the adaptor proteins crkl and c-crk link c-abl, p190(bcr/ abl) and p210(bcr/abl) to the phosphatidylinositol-3′ kinase pathway. Oncogene 12:839, 1996
    • (1996) Oncogene , vol.12 , pp. 839
    • Sattler, M.1    Salgia, R.2    Okuda, K.3    Uemura, N.4    Durstin, M.A.5    Pisick, E.6    Xu, G.7    Li, J.L.8    Prasad, K.V.9    Griffin, J.D.10
  • 18
    • 3643134318 scopus 로고
    • Multiple nuclear localization signals control the cytostatic effect of c-ABL
    • abstr
    • Van Etten RA, Wen S-T, Jackson PK: Multiple nuclear localization signals control the cytostatic effect of c-ABL. Blood 86:324a, 1995 (abstr, suppl 1)
    • (1995) Blood , vol.86 , Issue.SUPPL. 1
    • Van Etten, R.A.1    Wen, S.-T.2    Jackson, P.K.3
  • 19
    • 0028972103 scopus 로고
    • The SH2 domain of P210BCR/ABL is not required for the transformation of hematopoietic factor-dependent cells
    • Ilaria R Jr, Van Etten RA: The SH2 domain of P210BCR/ABL is not required for the transformation of hematopoietic factor-dependent cells. Blood 86:3897, 1995
    • (1995) Blood , vol.86 , pp. 3897
    • Ilaria Jr., R.1    Van Etten, R.A.2
  • 20
    • 0022274007 scopus 로고
    • IL-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo
    • Palacios R, Steinmetz M: IL-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo. Cell 41:727, 1985
    • (1985) Cell , vol.41 , pp. 727
    • Palacios, R.1    Steinmetz, M.2
  • 21
    • 0026063514 scopus 로고
    • The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains
    • D'Andrea AD, Yoshimura A, Youssoufian H, Zon LI, Koo JW, Lodish HF: The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains. Mol Cell Biol 11:1980, 1991
    • (1991) Mol Cell Biol , vol.11 , pp. 1980
    • D'Andrea, A.D.1    Yoshimura, A.2    Youssoufian, H.3    Zon, L.I.4    Koo, J.W.5    Lodish, H.F.6
  • 22
    • 0029845079 scopus 로고    scopus 로고
    • P210BCR/ABL, p190BCR/ABL, and TEL/ABL activate similar signal transduction pathways in hematopoietic cell lines
    • Okuda K, Golub TR, Gilliland DG, Griffin JD: p210BCR/ABL, p190BCR/ABL, and TEL/ABL activate similar signal transduction pathways in hematopoietic cell lines. Oncogene 13:1147, 1996
    • (1996) Oncogene , vol.13 , pp. 1147
    • Okuda, K.1    Golub, T.R.2    Gilliland, D.G.3    Griffin, J.D.4
  • 23
    • 0028348236 scopus 로고
    • A dominant negative erythropoietin(EPO) receptor inhibits EPO-dependent growth and blocks F-gp55-dependent transformation
    • Barber DE, DeMartino JC, Showers MO, D'Andrea AD: A dominant negative erythropoietin(EPO) receptor inhibits EPO-dependent growth and blocks F-gp55-dependent transformation. Mol Cell Biol 14:2257, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 2257
    • Barber, D.E.1    DeMartino, J.C.2    Showers, M.O.3    D'Andrea, A.D.4
  • 24
    • 0026781036 scopus 로고
    • Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines
    • Druker B, Okuda K, Matulonis U, Salgia R, Roberts T, Griffin JD: Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines. Blood 79:2215, 1992
    • (1992) Blood , vol.79 , pp. 2215
    • Druker, B.1    Okuda, K.2    Matulonis, U.3    Salgia, R.4    Roberts, T.5    Griffin, J.D.6
  • 26
    • 0025822797 scopus 로고
    • Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene
    • Kelliher M, Knott A, McLaughlin J, Witte ON, Rosenberg N: Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene. Mol Cell Biol 11:4710, 1991
    • (1991) Mol Cell Biol , vol.11 , pp. 4710
    • Kelliher, M.1    Knott, A.2    McLaughlin, J.3    Witte, O.N.4    Rosenberg, N.5
  • 27
    • 0029816460 scopus 로고    scopus 로고
    • The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype
    • Melo JV: The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype [editorial; comment]. Blood 88: 2375, 1996
    • (1996) Blood , vol.88 , pp. 2375
    • Melo, J.V.1
  • 31
    • 0028006156 scopus 로고
    • Use of a temperature sensitive mutant to define the biological effects of the p210bcr/abl tyrosine kinase on proliferation of a factor-dependent murine myeloid cell line
    • Carlesso N, Griffin JD, Druker BJ: Use of a temperature sensitive mutant to define the biological effects of the p210bcr/abl tyrosine kinase on proliferation of a factor-dependent murine myeloid cell line. Oncogene 9:149, 1994
    • (1994) Oncogene , vol.9 , pp. 149
    • Carlesso, N.1    Griffin, J.D.2    Druker, B.J.3
  • 32
    • 0028559163 scopus 로고
    • A temperature sensitive p210 BCR-ABL mutant defines the primary consequences of BCR-ABL tyrosine kinase expression in growth factor dependent cells
    • Kabarowski JH, Alien PB, Wiedemann LM: A temperature sensitive p210 BCR-ABL mutant defines the primary consequences of BCR-ABL tyrosine kinase expression in growth factor dependent cells. EMBO J 13:5887, 1994
    • (1994) EMBO J , vol.13 , pp. 5887
    • Kabarowski, J.H.1    Alien, P.B.2    Wiedemann, L.M.3
  • 33
    • 0027292483 scopus 로고
    • Hormone-conditional transformation by fusion proteins of c-Abl and its transforming variants
    • Jackson P, Baltimore D, Picard D: Hormone-conditional transformation by fusion proteins of c-Abl and its transforming variants. EMBO J 12:2809, 1993
    • (1993) EMBO J , vol.12 , pp. 2809
    • Jackson, P.1    Baltimore, D.2    Picard, D.3
  • 34
    • 3643052988 scopus 로고    scopus 로고
    • Activation of c-ABL kinase activity and transformation by a chemical inducer of dimerization
    • abstr
    • Van Etten RA, Smith K: Activation of c-ABL kinase activity and transformation by a chemical inducer of dimerization. Blood 90:247a, 1997 (abstr, suppl 1)
    • (1997) Blood , vol.90 , Issue.SUPPL. 1
    • Van Etten, R.A.1    Smith, K.2
  • 35
    • 0007894640 scopus 로고    scopus 로고
    • Secondary mutation maintains the transformed state in BaF3 cells with inducible BCR/ABL expression
    • abstr
    • Klucher KM, Lopez DV, Daley GQ: Secondary mutation maintains the transformed state in BaF3 cells with inducible BCR/ABL expression. Blood 90:179a, 1997 (abstr, suppl 1)
    • (1997) Blood , vol.90 , Issue.SUPPL. 1
    • Klucher, K.M.1    Lopez, D.V.2    Daley, G.Q.3
  • 36
    • 0022003801 scopus 로고
    • Localization of tyrosine kinase-coding region in v-abl oncogene by the expression of v-abl-encoded proteins in bacteria
    • Wang JY, Baltimore D: Localization of tyrosine kinase-coding region in v-abl oncogene by the expression of v-abl-encoded proteins in bacteria. J Biol Chem 260:64, 1985
    • (1985) J Biol Chem , vol.260 , pp. 64
    • Wang, J.Y.1    Baltimore, D.2
  • 39
    • 0028142490 scopus 로고
    • Crkl is the major tyrosine-phosphorylated protein in neutrophils from patients with chronic myelogenous leukemia
    • Oda T, Heaney C, Hagopian JR, Okuda K, Griffin JD, Druker BJ: Crkl is the major tyrosine-phosphorylated protein in neutrophils from patients with chronic myelogenous leukemia. J Biol Chem 269:22925, 1994
    • (1994) J Biol Chem , vol.269 , pp. 22925
    • Oda, T.1    Heaney, C.2    Hagopian, J.R.3    Okuda, K.4    Griffin, J.D.5    Druker, B.J.6
  • 40
    • 0028899930 scopus 로고
    • The SH2 domain of ABL is not required for factor-independent growth induced by BCR-ABL in a murine myeloid cell line
    • Oda T, Tamura S, Matsuguchi T, Griffin JD, Druker BJ: The SH2 domain of ABL is not required for factor-independent growth induced by BCR-ABL in a murine myeloid cell line. Leukemia 9:295, 1995
    • (1995) Leukemia , vol.9 , pp. 295
    • Oda, T.1    Tamura, S.2    Matsuguchi, T.3    Griffin, J.D.4    Druker, B.J.5
  • 41
    • 0026601293 scopus 로고
    • Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo
    • Mayer BJ, Jackson PK, Van Etten RA, Baltimore D: Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo. Mol Cell Biol 12:609, 1992
    • (1992) Mol Cell Biol , vol.12 , pp. 609
    • Mayer, B.J.1    Jackson, P.K.2    Van Etten, R.A.3    Baltimore, D.4
  • 43
    • 0030929394 scopus 로고    scopus 로고
    • Identification and characterization of two novel SH2 domain-containing proteins from a yeast two hybrid screen with the ABL tyrosine kinase
    • Oda T, Kujovich J, Reis M, Newman B, Druker BJ: Identification and characterization of two novel SH2 domain-containing proteins from a yeast two hybrid screen with the ABL tyrosine kinase. Oncogene 15:1255, 1997
    • (1997) Oncogene , vol.15 , pp. 1255
    • Oda, T.1    Kujovich, J.2    Reis, M.3    Newman, B.4    Druker, B.J.5
  • 44
    • 0031459864 scopus 로고    scopus 로고
    • P62(dok): A constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells
    • Carpino N, Wisniewski D, Strife A, Marshak D, Kobayashi R, Stillman B, Clarkson B: p62(dok): A constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells. Cell 88:197, 1997
    • (1997) Cell , vol.88 , pp. 197
    • Carpino, N.1    Wisniewski, D.2    Strife, A.3    Marshak, D.4    Kobayashi, R.5    Stillman, B.6    Clarkson, B.7
  • 45
    • 0029072404 scopus 로고
    • Introduction of a loss-of-function point mutation from the SH3 region of the Caenorhabditis elegans sem-5 gene activates the transforming ability of c-abl in vivo and abolishes binding of proline-rich ligands in vitro
    • Van Etten RA, Debnath J, Zhou H, Casasnovas JM: Introduction of a loss-of-function point mutation from the SH3 region of the Caenorhabditis elegans sem-5 gene activates the transforming ability of c-abl in vivo and abolishes binding of proline-rich ligands in vitro. Oncogene 10:1977, 1995
    • (1995) Oncogene , vol.10 , pp. 1977
    • Van Etten, R.A.1    Debnath, J.2    Zhou, H.3    Casasnovas, J.M.4
  • 46
    • 0028844631 scopus 로고
    • Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity
    • Shi Y, Alin K, Goff SP: Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity. Genes Dev 9:2583, 1995
    • (1995) Genes Dev , vol.9 , pp. 2583
    • Shi, Y.1    Alin, K.2    Goff, S.P.3
  • 47
    • 0030803669 scopus 로고    scopus 로고
    • The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity
    • Wen ST, Van Etten RA: The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity. Genes Dev 11:2456, 1997
    • (1997) Genes Dev , vol.11 , pp. 2456
    • Wen, S.T.1    Van Etten, R.A.2
  • 50
    • 0024353722 scopus 로고
    • The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization
    • Van Etten RA, Jackson P, Baltimore D: The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization. Cell 58:669, 1989
    • (1989) Cell , vol.58 , pp. 669
    • Van Etten, R.A.1    Jackson, P.2    Baltimore, D.3
  • 52
    • 0027367245 scopus 로고
    • Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation
    • Wetzler M, Talpaz M, Van Etten RA, Hirsh-Ginsberg C, Beran M, Kurzrock R: Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation. J Clin Invest 92:1925, 1993
    • (1993) J Clin Invest , vol.92 , pp. 1925
    • Wetzler, M.1    Talpaz, M.2    Van Etten, R.A.3    Hirsh-Ginsberg, C.4    Beran, M.5    Kurzrock, R.6
  • 53
    • 0026441040 scopus 로고
    • Mechanisms underlying abnormal trafficking of malignant progenitors in chronic myelogenous leukemia
    • Verfaillie CM, McCarthy JB, McGlave PB; Mechanisms underlying abnormal trafficking of malignant progenitors in chronic myelogenous leukemia. J Clin Invest 90:1232, 1992
    • (1992) J Clin Invest , vol.90 , pp. 1232
    • Verfaillie, C.M.1    McCarthy, J.B.2    McGlave, P.B.3
  • 54
    • 0030038231 scopus 로고    scopus 로고
    • Bcr/Abl expression stimulates integrin function in hematopoietic cell lines
    • Bazzoni G, Carlesso N, Griffin JD, Hemler ME: Bcr/Abl expression stimulates integrin function in hematopoietic cell lines. J Clin Invest 98:521, 1996
    • (1996) J Clin Invest , vol.98 , pp. 521
    • Bazzoni, G.1    Carlesso, N.2    Griffin, J.D.3    Hemler, M.E.4
  • 55
    • 0027536793 scopus 로고
    • An actin-binding function contributes to transformation by the Bcr-Abl oncoprotein of Philadelphia chromosome-positive human leukemias
    • McWhirter JR, Wang JY: An actin-binding function contributes to transformation by the Bcr-Abl oncoprotein of Philadelphia chromosome-positive human leukemias. EMBO J 12:1533, 1993
    • (1993) EMBO J , vol.12 , pp. 1533
    • McWhirter, J.R.1    Wang, J.Y.2


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