Xenospecific cytotoxic T lymphocytes: Potent lysis in vitro and in vivo

Transplantation

Volumn 63, Issue 8, 1997, Pages 1171-1178

  Smyth, Mark J ^a   Kershaw, Michael H ^a   Trapani, Joseph A ^a  

^a AUSTIN RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; FAS ANTIGEN; PERFORIN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; HUMAN; HUMAN CELL; LYMPHOCYTE DEPLETION; LYMPHOCYTOTOXICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; TARGET CELL DESTRUCTION; XENOTRANSPLANTATION;

EID: 0030942793     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199704270-00019     Document Type: Article

References (31)

1. Kagi D, Ledermann B, Burki K, et al. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 1994; 369: 31.
2. Walsh CM, Matloubian M, Liu C-C, et al. Immune function in mice lacking the perform gene. Proc Natl Acad Sci USA 1994; 91: 10854.
3. + T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity. Eur J Immunol 1994; 24: 3068.
4. 2+-independent T cell-mediated cytotoxicity. J Exp Med 1993; 177: 195.
5. Suda T, Nagata S. Purification and characterization of the Fasligand that induces apoptosis. J Exp Med 1994; 179: 873.
6. Zheng L, Fisher G, Miller RE, Peschon J, Lynch DH, Lenardo MJ. Induction of apoptosis in mature T cells by tumour necrosis factor. Nature 1995; 377: 348.
7. Singer G, Abbas AK. The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1994; 1: 365.
8. Russell JH, Rush B, Weaver C, Wang R. Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc Natl Acad Sci USA 1993; 90: 4409.
9. Kagi D, Vignaux F, Ledermann B, et al. Fas and perform pathways as major mechanisms of T cell-mediated cytotoxicity. Science 1994; 265: 528.
10. + cytotoxic T cells. Proc Natl Acad Sci USA 1994; 91: 4185.
11. Carter LL, Dutton RW. Relative perforin- and Fas-mediated lysis in T1 and T2 CDS effector populations. J Immunol 1995; 155: 1028.
12. Arase H, Arase N, Saito T. Fas-mediated cytotoxicity by freshly isolated natural killer cells. J Exp Med 1995; 181: 1235.
13. Sandrin MS, Fodor WL, Mouhtouris E, et al. Enzymatic remodelling of the carbohydrate surface of a xenogenic cell substantially reduces human antibody binding and complement-mediated cytolysis. Nature Med 1995; 1: 1261.
14. Auchincloss H. Xenogeneic transplantation. Transplantation 1988; 46: 1.
15. Auchincloss H Jr. Why is cell-mediated xenograft rejection so strong? Xenotransplantation 1995; 3: 19.
16. Seebach JD, Yamada K, McMorrow IM, Sachs DH, DerSimonian HD. Xenogeneic human anti-pig cytotoxicity mediated by activated natural killer cells. Xenotransplantation 1996; 3: 188.
17. + or B lymphocytes, can reject xenogeneic skin grafts. Xenotransplantation 1994; 1: 8.
18. + T cell-depleted diabetic mice. Transplantation 1990; 50: 657.
19. Schulz M, Schuurman H-J, Joergensen J, et al. Acute rejection of vascular heart allografts by perforin-deficient mice. Eur J Immunol 1995; 25: 474.
20. Walsh CM, Hayashi F, Saffran DC, Ju S-T, Berke G, Clark WR. Cell-mediated cytotoxicity results from, but may not be critical for, primary allograft rejection. J Immunol 1995; 156: 1436.
21. Larsen CP, Alexander DZ, Hendrix R, Ritchie SC, Pearson TC. Fas-mediated cytotoxicity: an immunoeffector or immunoregulatory pathway in T cell-mediated immune responses? Transplantation 1995; 60: 221.
22. Semple TU, Quinn LA, Woods LF, Moore FE. Tumor and lymphoid cell lines from a patient with carcinoma of the colon for a cytotoxicity model. Cancer Res 1978; 38: 1345.
23. Conzelmann A, Corthesy P, Cianfriglia M, Silva A, Nabholz M. Hybrids between rat lymphoma and mouse T cells with inducible cytolytic activity. Nature 1982; 298: 170.
24. + T cells. Science 1990; 248: 1227.
25. Henkart PA. Lymphocyte-mediated cytotoxicity: two pathways and multiple effector molecules. Immunity 1994; 1: 343.
26. Liu CC, Walsh CM, Young JD. Perforin: structure and function. Immunol Today 1995; 16: 194.
27. Englehard VH, Benjamin C. Xenogeneic cytotoxic T-cell clones recognize alloantigenic determinants on HLA-A2. Immunogenetics 1983; 18: 461.
28. Kos F, Engleman EG. Requirement for natural killer cells in the induction of cytotoxic T cells. J Immunol 1995; 155: 578.
29. Kurosawa S, Harada M, Matsuzaki G, et al. Early-appearing tumour-infiltrating natural killer cells play a crucial role in the generation of anti-tumour T lymphocytes. Immunology 1995; 85: 338.
30. Kos F, Engleman EG. Immune regulation: a critical link between NK cells and CTLs. Immunol Today 1996; 17: 173.
31. Romagnani S. Induction of TH1 and TH2 responses: a key role for the "natural" immune response? Immunol Today 1992; 13: 379.