Following antigen challenge, T cells up-regulate cell surface expression of CD4 in vitro and in vivo

Journal of Immunology

Volumn 161, Issue 2, 1998, Pages 714-720

  Ridgway, William ^a   Fassò, Marcella ^a   Fathman, C Garrison ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; ANTIGENS; ANTIGENS, CD4; CD4-POSITIVE T-LYMPHOCYTES; CELL MEMBRANE; CELLS, CULTURED; EPITOPES, T-LYMPHOCYTE; LYMPH NODES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MICE; MICE, INBRED DBA; MYOGLOBIN; STEM CELLS; T-LYMPHOCYTE SUBSETS; UP-REGULATION; WHALES;

EID: 0032528417     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Ford, D., and D. Burger. 1983. Precursor frequency of antigen-specific T cells: effects of sensitization in vivo and in vitro. Cell. Immunol. 79:334.
2. Gebel, H. M., J. R. Scott, C. A. Parvin, and G. E. Rodey. 1983. In vitro immunization to KLH: limiting dilution analysis of antigen-reactive cells in primary and secondary culture. J. Immunol. 130:29.
3. Kojima, M., K. B. Cease, G. K. Buckenmeyer, and J. A. Berzofsky. 1988. Limiting dilution comparison of the repertoires of high and low responder MHC-restricted T cells. J. Exp. Med. 167:1100.
4. Weyand, C. M., J. Goronzy, M. J. Dallman, and C. G. Fathman. 1986. Administration of recombinant interleukin 2 in vivo induces a polyclonal IgM response. J. Exp. Med. 163:1607.
5. Livingstone, A., and C. G. Fathman. 1987. Murine T cell clones. Methods Enzymol. 150:324.
6. Kearney, E. R., K. A. Pape, D. Y. Loh, and M. K. Jenkins. 1994. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1:327.
7. + T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4. J. Immunol. 155:1032.
8. Altman, J. D., P. A. H. Moss, P. J. R. Goulder, D. H. Barouch, M. G. McHeyzer-Williams, J. I. Bell, A. J. McMichael, and M. M. Davis. 1996. Phenotypic analysis of antigen-specific T lymphocytes. Science 274:94.
9. McHeyzer-Williams, M. G., and M. M. Davis. 1995. Antigen-specific development of primary and memory T cells in vivo. Science 268:106.
10. McHeyzer-Williams, M. G., J. D. Altman, and M. M. Davis. 1996. Tracking antigen-specific helper T cell responses. Curr. Opin. Immunol. 8:278.
11. McHeyzer-Williams, M. G., J. D. Altman, and M. M. Davis. 1996. Enumeration and characterization of memory cells in the TH compartment. Immunol. Rev. 150:5.
12. Davis, M. M., M. McHeyzer-Williams, and Y. H. Chien. 1995. T-cell receptor V-region usage and antigen-specificity: the cytochrome c model system. Ann. N Y Acad. Sci. 756:1.
13. Danska, J. S., A. M. Livingstone, V. Paragas, T. Ishihara, and C. G. Fathman. 1990. The presumptive CDR3 regions of both T cell receptor alpha and beta chains determine T cell specificity for myoglobin peptides. J. Exp. Med. 172:27.
14. Ruberti, G., A. Gaur, C. G. Fathman, and A. M. Livingstone. 1991. The T cell receptor repertoire influences V beta element usage in response to myoglobin. J. Exp. Med. 174:83.
15. Ruberti, G., V. Paragas, D. Kim, and C. G. Fathman. 1993. Selection for amino acid sequence and J β element usage in the β chain of DBA/2V β b- and DBA/2V β a-derived myoglobin-specific T cell clones. J. Immunol. 151:6185.
16. + helper T lymphocytes identified by expression of pgp-1. J. Exp. Med. 169:1461.
17. Evavold, B. D., and P. M. Allen. 1991. Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand. Science 252:1308.
18. Evavold, B. D., S. G. Williams, B. L. Hsu, S. Buus, and P. M. Allen. 1992. Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T cell hybridomas. J. Immunol. 148:347.
19. Evavold, B. D., J. Sloan-Lancaster, B. L. Hsu, and P. M. Allen. 1993. Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides. J. Immunol. 150:3131.
20. + T cell-stimulating antigen of pathogenic bacteria by expression cloning. J. Exp. Med. 182:1751.
21. Kelly, K., K. Shortman, and R. Scollay. 1988. The surface phenotype of activated T lymphocytes. Immunol. Cell Biol. 66:297.
22. Solbach, W. 1982. Tumor-promoting phorbol esters selectively abrogate the expression of the T4 differentiation antigen expressed on normal and malignant (Sezary) T helper lymphocytes. J. Exp. Med. 156:1250.
23. Cassel, D. L., J. A. Hoxie, and R. A. Cooper. 1983. Phorbol ester modulation of T-cell antigens in the Jurkat lymphoblastic leukemia cell line. Cancer Res. 43: 4582.
24. Janeway, C., Jr. 1991. The co-receptor function of CD4. Semin. Immunol. 3:153.
25. Janeway, C., Jr. 1992. The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation. Annu. Rev. Immunol. 10:645.
26. Dianzani, U., A. Shaw, B. K. al-Ramadi, R. T. Kubo, and C. Janeway, Jr. 1992. Physical association of CD4 with the T cell receptor. J. Immunol. 148:678.
27. Konig, R., S. Fleury, and R. N. Germain. 1996. The structural basis of CD4-MHC class II interactions: coreceptor contributions to T cell receptor antigen recognition and oligomerization-dependent signal transduction. Curr Top Microbiol. Immunol. 205:19.