Linkage analysis and construction of a congenic strain for a blood pressure QTL on rat chromosome 9

Genomics

Volumn 51, Issue 2, 1998, Pages 191-196

  Rapp, John P ^a   Garrett, Michael R ^a   Dene, Howard ^a   Meng, Haijin ^a   Hoebee, Barbara ^b   Lathrop, G Mark ^c  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE REGULATION; CHROMOSOME 9; CHROMOSOME ANALYSIS; FOLLOW UP; GENE LOCUS; HEART WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; RAT; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ANIMALIA; RODENTIA;

EID: 0032528276     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1998.5394     Document Type: Article

References (36)

1. Aalkjaer C. Regulation of intracellular pH and its role in vascular smooth muscle regulation. J. Hypertens. 8:1990;197-206.
2. 2. Genome Res. 7:1997;434-440.
3. Blin N., Stafford D. W. Isolation of high-molecular-weight DNA. Nucleic Acids Res. 3:1976;2303-2308.
4. Bunag R., Butterfield J. Tail cuff blood pressure measurement without external preheating in awake rats. Hypertension. 4:1982;898-903.
5. Cicila, G. T. Choi, C. Dene, H. Lee, S. J. Rapp, J. P. 1998, Two blood pressure/cardiac mass quantitative trait loci on chromosome 3 in Dahl rats.
6. Cicila G. T., Dukhanina O. I., Kurtz T. W., Walder R., Garrett M. R., Dene H., Rapp J. P. Blood pressure and survival of a chromosome 7 congenic strain bred from Dahl rats. Mamm. Genome. 8:1997;896-902.
7. Cicila G. T., Rapp J. P., Bloch K. D., Kurtz T. W., Pravenec M., Kren V., Hong C.C., Quertermous T., Ng S. C. Cosegregation of the endothelin-3 locus with blood pressure and relative heart weight in inbred Dahl rats. J. Hypertens. 12:1994;643-651.
8. Cicila G. T., Rapp J. P., Wang J. M., St. Lezin E., Ng S. C, Kurtz T. W. Linkage of 11β-hydroxylase mutations with altered steroid biosynthesis and resistance to salt induced increases in blood pressure. Nat. Genet. 3:1993;346-353.
9. Dahl L. K., Heine M., Tassinari L. Effects of chronic excess salt ingestion play an important role in susceptibility to experimental hypertension. J. Exp. Med. 115:1963;1173-1190.
10. Deng A. Y., Gu L., Rapp J. P., Szpirer C., Szpirer J. Chromosomal assignment of 11 loci in the rat by mouse-rat somatic hybrids and linkage. Mamm. Genome. 5:1994;712-716.
11. Deng A. Y., Jackson C. M., Hoebee B., Rapp J. P. Mapping of rat chromosome 2 markers generated from chromosome-sorted DNA. Mamm. Genome. 8:1997a;731-735.
12. Deng A. Y., Jackson C. M., Hoebee B., Rapp J. P. Mapping of rat chromosome 5 markers generated from chromosome-sorted DNA. Mamm. Genome. 8:1997b;549-553.
13. Deng A. Y., Dene H., Rapp J. P. Congenic strains for the blood pressure quantitative trait locus on rat chromosome 2. Hypertension. 30:1997c;199-302.
14. Dukhanina O. I., Dene H., Deng A. Y., Choi C. R., Hoebee B., Rapp J. P. Linkage map and congenic strains to localize blood pressure QTL on rat chromosome 10. Mamm. Genome. 8:1997;229-235.
15. Garrett M. R., Dene H., Walder R., Zhang Q-Y., Cicila G. T., Assadnia S., Deng A. Y., Rapp J. P. Genomic scan and congenic strains for blood pressure QTL using Dahl salt-sensitive rats. Genome Res. 1998.
16. Hoebee B., de Stoppelaer J. M., Suijkerbuijk R. F., Monard S. Isolation of rat chromosome-specific paint probes by bivariate flow sorting followed by degenerate oligonucleotide primed-PCR. Cytogenet. Cell Genet. 66:1994;277-282.
17. Jacob H. J., Brown D. M., Bunker R. K., Daly M. J., Dzau V. J., Goodman A., Koike G., Kren V., Kurtz T., Lernmark A., Levan G., Mao Y-p., Pettersson A., Pravenec M., Simon J. S., Szpirer C., Szpirer J., Trolliet M. R., Winer E. S., Lander E. S. A genetic linkage map of the laboratory rat,Rattus norvegicus. Nat. Genet. 9:1995;63-69.
18. Kato, N. Hyne, G. Bihoreau, M-T. Gauguier, D. Lathrop, G. M. Rapp, J. P. 1998, Complete genome searches for quantitative trait loci controlling blood pressure and related traits in four segregating populations derived from Dahl hypertensive rats.
19. Lander E. S., Botstein D. Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics. 121:1989;185-199.
20. Lander E., Green P., Abrahamson J., Barlow A., Daly M., Lincoln S., Newburg L. Mapmaker: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics. 1:1987;174-181.
21. Lander E., Kruglyak L. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nat. Genet. 11:1995;241-247.
22. Lincoln, S. Daly, M. Lander, E. 1992a, Constructing genetic maps with Mapmaker/Exp 3.0, Whitehead Institute Technical Report, Whitehead Institute, Cambridge, MA.
23. Lincoln, S. Daly, M. Lander, E. 1992b, Mapping genes controlling quantitative traits with Mapmaker/QTL 1.1, Whitehead Institute Technical Report, Whitehead Institute, Cambridge, MA.
24. Matzuk M. M., Finegold M. J., Su J-G. J., Hsueh A. J. W. α-Inhibin is a tumour-suppressor gene with gonadal specificity in mice. Nature. 360:1992;313-319.
25. Paterson A., Lander E., Lincoln S., Hewitt J., Peterson S., Tanksley S. Resolution of quantitative traits into Mendelian factors using a complete RFLP linkage map. Nature. 335:1988;721-726.
26. ++. Hypertension. 29:1997;1265-1272.
27. Rapp J. P., Dene H. Development and characteristics of inbred strains of Dahl salt-sensitive and salt-resistance rats. Hypertension. 7:1985;340-349.
28. Rapp J. P., Dene H., Deng A. Y. Seven renin alleles and their effects on blood pressure. J. Hypertens. 12:1994;349-355.
29. Rapp J. P., Deng A. Y. Detection and positional cloning of blood pressure quantitative trait loci: Is it possible. Hypertension. 25:1995;1121-1128.
30. Rapp J. P., Wang S-M., Dene H. A genetic polymorphism in the renin gene of Dahl rats cosegregates with blood pressure. Science. 243:1989;542-544.
31. Serikawa T., Kuramoto T., Hilbert P., Mori M., Yamada J., Dubay C. J., Lindpaintner K., Ganten D., Guénet J-L., Lathrop G. M., Beckmann J. S. Rat gene mapping using PCR-analyzed microsatellites. Genetics. 131:1992;701-721.
32. Silver L. M. Mouse Genetics, Concepts and Applications. 1995;Oxford Univ. Press, New York. p. 49.
33. Swales J. D. Textbook of Hypertension. 1994;Blackwell, Cambridge. p. 164-165.
34. Szpirer C., Szpirer J., Rivière M., Levan G., Orlowski J. Chromosomal assignment of four genes encoding Na/H exchanger isoforms in human and rat. Mamm. Genome. 5:1994;153-159.
35. Walder, R. Y. Garrett, M. R. McClain, A. M. Beck, G. E. Brennan, T. M. H. Kramer, N. A. Kanis, A. B. Mark, A. L. Rapp, J. P. Sheffield, V. C. 1998, High quality polymorphic markers for the rat genome developed from marker-selected libraries.
36. Zhang Q. Y., Dene H., Deng A. Y., Garrett M. R., Jacob H. J., Rapp J. P. Interval mapping and congenic strains for a blood pressure QTL on rat chromosome 13. Mamm. Genome. 8:1997;636-641.