Interferon immunogenicity: Technical evaluation of interferon-α2a

Journal of Interferon and Cytokine Research

Volumn 17, Issue SUPPL. 1, 1997, Pages

  Hochuli, Erich ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2 INTERFERON; INTERFERON; INTERFERON ANTIBODY; NEUTRALIZING ANTIBODY; RECOMBINANT ALPHA2A INTERFERON; RECOMBINANT ALPHA2B INTERFERON;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; CONTROLLED STUDY; DRUG ANTIGENICITY; DRUG FORMULATION; DRUG STORAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOGENICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; REVIEW;

AMINO ACID SEQUENCE; ANIMALS; ESCHERICHIA COLI; HUMANS; HYDROGEN-ION CONCENTRATION; INTERFERON ALFA-2A; MICE; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PRESERVATION, BIOLOGICAL; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 0030803840     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (3)

1. BODO, G., and FOGY, I. (1985). Characterization of different molecular species in affinity purified recombinant human interferon alpha 2. In: The Interferon System. F. Dianzani and G. B. Rossi (eds.) New York: Raven Press, 24, 23-27.
2. GALTON, J.E., BEDFORD, P., SCOTT, J.E., BRAND, C.M., and NETHERSELL, A.B.W. (1989). Antibodies to lymphoblastoid interferon. Lancet 2, 572-573.
3. MOGENSEN, K.E., DAUBAS, P.H., GRESSER, I., SERENI, D., and VARET, B. (1981). Patients with circulating antibodies to α-interferon. Lancet 2, 1227-1228.