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Volumn 55, Issue 10, 1998, Pages 1683-1689

Concentrating capacity of the human reduced folate carrier (hRFC1) in human ZR-75 breast cancer cell lines

Author keywords

Folate; Methotrexate; Reduced folate carrier; Transport

Indexed keywords

CARRIER PROTEIN; METHOTREXATE; METHOTREXATE DERIVATIVE; POLYGLUTAMIC ACID; REDUCED FOLATE CARRIER; UNCLASSIFIED DRUG;

EID: 0032525038     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00039-2     Document Type: Article
Times cited : (9)

References (39)
  • 1
    • 0014410041 scopus 로고
    • Carrier-mediated transport of the folic acid analogue, methotrexate, in the L1210 leukemia cell
    • Goldman ID, Lichtenstein NS, Oliverio VT. Carrier-mediated transport of the folic acid analogue, methotrexate, in the L1210 leukemia cell. J Biol Chem. 243:1968;5007-5017.
    • (1968) J Biol Chem , vol.243 , pp. 5007-5017
    • Goldman, I.D.1    Lichtenstein, N.S.2    Oliverio, V.T.3
  • 2
    • 0021838288 scopus 로고
    • The cellular pharmacology of methotrexate
    • Goldman ID, Matherly LH. The cellular pharmacology of methotrexate. Pharmacol Ther. 28:1985;77-102.
    • (1985) Pharmacol Ther , vol.28 , pp. 77-102
    • Goldman, I.D.1    Matherly, L.H.2
  • 3
    • 0010597057 scopus 로고
    • Correlates of folate analog transport, pharmacokinetics and selective antitumor action
    • I.D. Goldman. Oxford: Pergamon Press
    • Sirotnak FM. Correlates of folate analog transport, pharmacokinetics and selective antitumor action. Goldman ID. Membrane Transport of Antineoplastic Agents. 1986;241-281 Pergamon Press, Oxford.
    • (1986) Membrane Transport of Antineoplastic Agents , pp. 241-281
    • Sirotnak, F.M.1
  • 4
    • 0025336152 scopus 로고
    • Folate-binding proteins
    • Henderson GB. Folate-binding proteins. Annu Rev Nutr. 10:1990;319-335.
    • (1990) Annu Rev Nutr , vol.10 , pp. 319-335
    • Henderson, G.B.1
  • 5
    • 0027982786 scopus 로고
    • A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells
    • Dixon KH, Lanpher BC, Chiu J, Kelley K, Cowan KH. A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells. J Biol Chem. 269:1994;17-20.
    • (1994) J Biol Chem , vol.269 , pp. 17-20
    • Dixon, K.H.1    Lanpher, B.C.2    Chiu, J.3    Kelley, K.4    Cowan, K.H.5
  • 6
    • 0029147794 scopus 로고
    • Isolation of a gene encoding a human reduced folate carrier (RFC1) and analysis of its expression in transport-deficient, methotrexate-resistant human breast cancer cells
    • Moscow JA, Gong MK, He R, Sgagias MK, Dixon KH, Anzick SL, Meltzer PS, Cowan KH. Isolation of a gene encoding a human reduced folate carrier (RFC1) and analysis of its expression in transport-deficient, methotrexate-resistant human breast cancer cells. Cancer Res. 55:1995;3790-3794.
    • (1995) Cancer Res , vol.55 , pp. 3790-3794
    • Moscow, J.A.1    Gong, M.K.2    He, R.3    Sgagias, M.K.4    Dixon, K.H.5    Anzick, S.L.6    Meltzer, P.S.7    Cowan, K.H.8
  • 7
    • 0029084385 scopus 로고
    • Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells
    • Wong SC, Proefke SA, Bhushan A, Matherly LH. Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells. J Biol Chem. 270:1995;17468-17475.
    • (1995) J Biol Chem , vol.270 , pp. 17468-17475
    • Wong, S.C.1    Proefke, S.A.2    Bhushan, A.3    Matherly, L.H.4
  • 8
    • 0027963626 scopus 로고
    • Isolation of a hamster cDNA clone coding for a function involved in methotrexate uptake
    • Williams FMR, Murray RC, Underhill TM, Flintoff WF. Isolation of a hamster cDNA clone coding for a function involved in methotrexate uptake. J Biol Chem. 269:1994;5810-5816.
    • (1994) J Biol Chem , vol.269 , pp. 5810-5816
    • Williams, F.M.R.1    Murray, R.C.2    Underhill, T.M.3    Flintoff, W.F.4
  • 9
    • 0028887425 scopus 로고
    • Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake
    • Williams FMR, Flintoff WF. Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake. J Biol Chem. 270:1995;2987-2992.
    • (1995) J Biol Chem , vol.270 , pp. 2987-2992
    • Williams, F.M.R.1    Flintoff, W.F.2
  • 11
    • 0015246387 scopus 로고
    • The characteristics of the membrane transport of amethopterin and the naturally occurring folates
    • Goldman ID. The characteristics of the membrane transport of amethopterin and the naturally occurring folates. Ann NY Acad Sci. 186:1971;400-422.
    • (1971) Ann NY Acad Sci , vol.186 , pp. 400-422
    • Goldman, I.D.1
  • 12
    • 0021152014 scopus 로고
    • Interaction between anions and the reduced folate/methotrexate transport system in L1210 cell plasma membrane vesicles: Directional symmetry and anion specificity for differential mobility of loaded and unloaded carrier
    • Yang C-H, Sirotnak FM, Dembo M. Interaction between anions and the reduced folate/methotrexate transport system in L1210 cell plasma membrane vesicles Directional symmetry and anion specificity for differential mobility of loaded and unloaded carrier . J Membr Biol. 79:1984;285-292.
    • (1984) J Membr Biol , vol.79 , pp. 285-292
    • Yang C-H1    Sirotnak, F.M.2    Dembo, M.3
  • 13
    • 0020957864 scopus 로고
    • Structural requirements for anion substrates of the methotrexate transport system of L1210 cells
    • Henderson GB, Zevely EM. Structural requirements for anion substrates of the methotrexate transport system of L1210 cells. Arch Biochem Biophys. 221:1983;438-446.
    • (1983) Arch Biochem Biophys , vol.221 , pp. 438-446
    • Henderson, G.B.1    Zevely, E.M.2
  • 14
    • 0019851443 scopus 로고
    • Anion exchange mechanism for transport of methotrexate in L1210 cells
    • Henderson GB, Zevely EM. Anion exchange mechanism for transport of methotrexate in L1210 cells. Biochem Biophys Res Commun. 99:1981;163-169.
    • (1981) Biochem Biophys Res Commun , vol.99 , pp. 163-169
    • Henderson, G.B.1    Zevely, E.M.2
  • 15
    • 0020025052 scopus 로고
    • Intracellular phosphate and its possible role as an exchange anion for active transport of methotrexate in L1210 cells
    • Henderson GB, Zevely EM. Intracellular phosphate and its possible role as an exchange anion for active transport of methotrexate in L1210 cells. Biochem Biophys Res Commun. 104:1982;474-482.
    • (1982) Biochem Biophys Res Commun , vol.104 , pp. 474-482
    • Henderson, G.B.1    Zevely, E.M.2
  • 16
    • 0025952140 scopus 로고
    • Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement
    • Brigle KE, Westin EH, Houghton MT, Goldman ID. Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement. J Biol Chem. 266:1991;17243-17249.
    • (1991) J Biol Chem , vol.266 , pp. 17243-17249
    • Brigle, K.E.1    Westin, E.H.2    Houghton, M.T.3    Goldman, I.D.4
  • 17
    • 0028986856 scopus 로고
    • Distinguishing between folate receptor-α-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells
    • Spinella MJ, Brigle KE, Sierra EE, Goldman ID. Distinguishing between folate receptor-α-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells. J Biol Chem. 270:1995;7842-7849.
    • (1995) J Biol Chem , vol.270 , pp. 7842-7849
    • Spinella, M.J.1    Brigle, K.E.2    Sierra, E.E.3    Goldman, I.D.4
  • 18
    • 0026652116 scopus 로고
    • The biological chemistry of folate receptors
    • Antony AC. The biological chemistry of folate receptors. Blood. 79:1992;2807-2820.
    • (1992) Blood , vol.79 , pp. 2807-2820
    • Antony, A.C.1
  • 19
    • 0023683407 scopus 로고
    • Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles
    • Kamen BA, Wang M, Streckfuss AJ, Peryea X, Anderson RGW. Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles. J Biol Chem. 263:1988;13602-13609.
    • (1988) J Biol Chem , vol.263 , pp. 13602-13609
    • Kamen, B.A.1    Wang, M.2    Streckfuss, A.J.3    Peryea, X.4    Anderson, R.G.W.5
  • 20
    • 0025303751 scopus 로고
    • The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway
    • Rothberg KG, Ying Y, Kolhouse JF, Kamen BA, Anderson RGW. The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway. J Cell Biol. 110:1990;637-649.
    • (1990) J Cell Biol , vol.110 , pp. 637-649
    • Rothberg, K.G.1    Ying, Y.2    Kolhouse, J.F.3    Kamen, B.A.4    Anderson, R.G.W.5
  • 21
    • 0025275523 scopus 로고
    • Characteristics of a novel transport system for folate compounds in wild-type and methotrexate-resistant L1210 cells
    • Henderson GB, Strauss BP. Characteristics of a novel transport system for folate compounds in wild-type and methotrexate-resistant L1210 cells. Cancer Res. 50:1990;1709-1714.
    • (1990) Cancer Res , vol.50 , pp. 1709-1714
    • Henderson, G.B.1    Strauss, B.P.2
  • 22
    • 0031021010 scopus 로고    scopus 로고
    • PH dependence of methotrexate transport by the reduced folate carrier and the folate receptor in L1210 leukemia cells. Further evidence for a third route mediated at low pH
    • Sierra EE, Brigle KE, Spinella MJ, Goldman ID. pH dependence of methotrexate transport by the reduced folate carrier and the folate receptor in L1210 leukemia cells. Further evidence for a third route mediated at low pH. Biochem Pharmacol. 53:1997;223-231.
    • (1997) Biochem Pharmacol , vol.53 , pp. 223-231
    • Sierra, E.E.1    Brigle, K.E.2    Spinella, M.J.3    Goldman, I.D.4
  • 23
    • 0014690663 scopus 로고
    • Transport energetics of the folic acid analogue, methotrexate, in L1210 cells: Enhanced accumulation by metabolic inhibitors
    • Goldman ID. Transport energetics of the folic acid analogue, methotrexate, in L1210 cells Enhanced accumulation by metabolic inhibitors . J Biol Chem. 244:1969;3779-3785.
    • (1969) J Biol Chem , vol.244 , pp. 3779-3785
    • Goldman, I.D.1
  • 24
    • 0026761157 scopus 로고
    • Separation and inhibitor specificity of a second unidirectional efflux route for methotrexate in L1210 cells
    • Henderson GB. Separation and inhibitor specificity of a second unidirectional efflux route for methotrexate in L1210 cells. Biochim Biophys Acta. 1110:1992;137-143.
    • (1992) Biochim Biophys Acta , vol.1110 , pp. 137-143
    • Henderson, G.B.1
  • 25
    • 0026741788 scopus 로고
    • Energy-dependent efflux of methotrexate in L1210 leukemia cells. Evidence for the role of an ATPase obtained with inside-out plasma membrane vesicles
    • Schlemmer SR, Sirotnak FM. Energy-dependent efflux of methotrexate in L1210 leukemia cells. Evidence for the role of an ATPase obtained with inside-out plasma membrane vesicles. J Biol Chem. 267:1992;14746-14752.
    • (1992) J Biol Chem , vol.267 , pp. 14746-14752
    • Schlemmer, S.R.1    Sirotnak, F.M.2
  • 26
    • 0030758278 scopus 로고    scopus 로고
    • Impact of overexpression of the reduced folate carrier (RFC1), an anion exchanger, on concentrative transport in murine L1210 leukemia cells
    • Zhao R, Seither R, Brigle KE, Sharina IG, Wang PJ, Goldman ID. Impact of overexpression of the reduced folate carrier (RFC1), an anion exchanger, on concentrative transport in murine L1210 leukemia cells. J Biol Chem. 272:1997;21207-21212.
    • (1997) J Biol Chem , vol.272 , pp. 21207-21212
    • Zhao, R.1    Seither, R.2    Brigle, K.E.3    Sharina, I.G.4    Wang, P.J.5    Goldman, I.D.6
  • 27
    • 0021720510 scopus 로고
    • A novel class of genetic varients of the L1210 cell up-regulated for folate analogue transport inward
    • Sirotnak FM, Moccio DM, Yang C-H. A novel class of genetic varients of the L1210 cell up-regulated for folate analogue transport inward. J Biol Chem. 259:1984;13139-13144.
    • (1984) J Biol Chem , vol.259 , pp. 13139-13144
    • Sirotnak, F.M.1    Moccio, D.M.2    Yang C-H3
  • 28
    • 0025016121 scopus 로고
    • Methotrexate transport in variant human CCRF-CEM leukemia cells with elevated levels of the reduced folate carrier. Selective effect on carrier-mediated transport of physiological concentrations of reduced folates
    • Jansen G, Westerhof GR, Jarmuszewski MJA, Kathmann I, Rijksen G, Schornagel JH. Methotrexate transport in variant human CCRF-CEM leukemia cells with elevated levels of the reduced folate carrier. Selective effect on carrier-mediated transport of physiological concentrations of reduced folates. J Biol Chem. 265:1990;18272-18277.
    • (1990) J Biol Chem , vol.265 , pp. 18272-18277
    • Jansen, G.1    Westerhof, G.R.2    Jarmuszewski, M.J.A.3    Kathmann, I.4    Rijksen, G.5    Schornagel, J.H.6
  • 29
    • 0026075874 scopus 로고
    • Identification of a highly glycosylated methotrexate membrane carrier in K562 human erythroleukemia cells up-regulated for tetrahydrofolate cofactor and methotrexate transport
    • Matherly LH, Czajkowski CA, Angeles SM. Identification of a highly glycosylated methotrexate membrane carrier in K562 human erythroleukemia cells up-regulated for tetrahydrofolate cofactor and methotrexate transport. Cancer Res. 51:1991;3420-3426.
    • (1991) Cancer Res , vol.51 , pp. 3420-3426
    • Matherly, L.H.1    Czajkowski, C.A.2    Angeles, S.M.3
  • 30
    • 0018079661 scopus 로고
    • Establishment and characterization of three new continuous cell lines derived from human breast carcinomas
    • Engel LW, Young NA, Tralka TS, Lippman ME, O'Brien SJ, Joyce MJ. Establishment and characterization of three new continuous cell lines derived from human breast carcinomas. Cancer Res. 38:1978;3352-3364.
    • (1978) Cancer Res , vol.38 , pp. 3352-3364
    • Engel, L.W.1    Young, N.A.2    Tralka, T.S.3    Lippman, M.E.4    O'Brien, S.J.5    Joyce, M.J.6
  • 31
    • 0021209446 scopus 로고
    • A methotrexate-resistant human breast cancer cell line with multiple defects, including diminished formation of methotrexate polyglutamates
    • Cowan KH, Jolivet J. A methotrexate-resistant human breast cancer cell line with multiple defects, including diminished formation of methotrexate polyglutamates. J Biol Chem. 259:1984;10793-10800.
    • (1984) J Biol Chem , vol.259 , pp. 10793-10800
    • Cowan, K.H.1    Jolivet, J.2
  • 32
    • 0008195538 scopus 로고    scopus 로고
    • Comparison of methotrexate polyglutamylation in L1210 leukemia cells when influx is mediated by the reduced folate carrier or the folate receptor. Lack of evidence for influx route-specific effects
    • Spinella MJ, Brigle KE, Freemantle SJ, Sierra EE, Goldman ID. Comparison of methotrexate polyglutamylation in L1210 leukemia cells when influx is mediated by the reduced folate carrier or the folate receptor. Lack of evidence for influx route-specific effects. Biochem Pharmacol. 52:1996;703-712.
    • (1996) Biochem Pharmacol , vol.52 , pp. 703-712
    • Spinella, M.J.1    Brigle, K.E.2    Freemantle, S.J.3    Sierra, E.E.4    Goldman, I.D.5
  • 33
    • 0000218191 scopus 로고
    • Purification and properties of dihydrofolate reductase from Ehrlich ascites carcinoma cells
    • Bertino JR, Perkins JP, Johns DG. Purification and properties of dihydrofolate reductase from Ehrlich ascites carcinoma cells. Biochemistry. 4:1965;839-846.
    • (1965) Biochemistry , vol.4 , pp. 839-846
    • Bertino, J.R.1    Perkins, J.P.2    Johns, D.G.3
  • 36
    • 0028111514 scopus 로고
    • Increased expression and genomic organization of a folate-binding protein homologous to the human placental isoform in L1210 murine leukemia cells with a defective reduced folate carrier
    • Brigle KE, Seither RL, Westin EH, Goldman ID. Increased expression and genomic organization of a folate-binding protein homologous to the human placental isoform in L1210 murine leukemia cells with a defective reduced folate carrier. J Biol Chem. 269:1994;4267-4272.
    • (1994) J Biol Chem , vol.269 , pp. 4267-4272
    • Brigle, K.E.1    Seither, R.L.2    Westin, E.H.3    Goldman, I.D.4
  • 37
    • 0020081481 scopus 로고
    • Rapid formation of poly-γ-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro
    • Fry DW, Yalowich JC, Goldman ID. Rapid formation of poly-γ-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro. J Biol Chem. 257:1982;1890-1896.
    • (1982) J Biol Chem , vol.257 , pp. 1890-1896
    • Fry, D.W.1    Yalowich, J.C.2    Goldman, I.D.3
  • 38
    • 0031012198 scopus 로고    scopus 로고
    • Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity
    • Wong SC, McQuade R, Proefke SA, Bhushan A, Matherly LH. Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity. Biochem Pharmacol. 53:1997;199-206.
    • (1997) Biochem Pharmacol , vol.53 , pp. 199-206
    • Wong, S.C.1    McQuade, R.2    Proefke, S.A.3    Bhushan, A.4    Matherly, L.H.5
  • 39
    • 0026403582 scopus 로고
    • Folate transport and the modulation of antifolate sensitivity in a methotrexate-resistant human breast cancer cell line
    • Dixon KH, Trepel JB, Eng SC, Cowan KH. Folate transport and the modulation of antifolate sensitivity in a methotrexate-resistant human breast cancer cell line. Cancer Commun. 3:1991;357-365.
    • (1991) Cancer Commun , vol.3 , pp. 357-365
    • Dixon, K.H.1    Trepel, J.B.2    Eng, S.C.3    Cowan, K.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.