-
1
-
-
0014410041
-
Carrier-mediated transport of the folic acid analogue, methotrexate, in the L1210 leukemia cell
-
Goldman ID, Lichtenstein NS, Oliverio VT. Carrier-mediated transport of the folic acid analogue, methotrexate, in the L1210 leukemia cell. J Biol Chem. 243:1968;5007-5017.
-
(1968)
J Biol Chem
, vol.243
, pp. 5007-5017
-
-
Goldman, I.D.1
Lichtenstein, N.S.2
Oliverio, V.T.3
-
2
-
-
0021838288
-
The cellular pharmacology of methotrexate
-
Goldman ID, Matherly LH. The cellular pharmacology of methotrexate. Pharmacol Ther. 28:1985;77-102.
-
(1985)
Pharmacol Ther
, vol.28
, pp. 77-102
-
-
Goldman, I.D.1
Matherly, L.H.2
-
3
-
-
0010597057
-
Correlates of folate analog transport, pharmacokinetics and selective antitumor action
-
I.D. Goldman. Oxford: Pergamon Press
-
Sirotnak FM. Correlates of folate analog transport, pharmacokinetics and selective antitumor action. Goldman ID. Membrane Transport of Antineoplastic Agents. 1986;241-281 Pergamon Press, Oxford.
-
(1986)
Membrane Transport of Antineoplastic Agents
, pp. 241-281
-
-
Sirotnak, F.M.1
-
4
-
-
0025336152
-
Folate-binding proteins
-
Henderson GB. Folate-binding proteins. Annu Rev Nutr. 10:1990;319-335.
-
(1990)
Annu Rev Nutr
, vol.10
, pp. 319-335
-
-
Henderson, G.B.1
-
5
-
-
0027982786
-
A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells
-
Dixon KH, Lanpher BC, Chiu J, Kelley K, Cowan KH. A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells. J Biol Chem. 269:1994;17-20.
-
(1994)
J Biol Chem
, vol.269
, pp. 17-20
-
-
Dixon, K.H.1
Lanpher, B.C.2
Chiu, J.3
Kelley, K.4
Cowan, K.H.5
-
6
-
-
0029147794
-
Isolation of a gene encoding a human reduced folate carrier (RFC1) and analysis of its expression in transport-deficient, methotrexate-resistant human breast cancer cells
-
Moscow JA, Gong MK, He R, Sgagias MK, Dixon KH, Anzick SL, Meltzer PS, Cowan KH. Isolation of a gene encoding a human reduced folate carrier (RFC1) and analysis of its expression in transport-deficient, methotrexate-resistant human breast cancer cells. Cancer Res. 55:1995;3790-3794.
-
(1995)
Cancer Res
, vol.55
, pp. 3790-3794
-
-
Moscow, J.A.1
Gong, M.K.2
He, R.3
Sgagias, M.K.4
Dixon, K.H.5
Anzick, S.L.6
Meltzer, P.S.7
Cowan, K.H.8
-
7
-
-
0029084385
-
Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells
-
Wong SC, Proefke SA, Bhushan A, Matherly LH. Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells. J Biol Chem. 270:1995;17468-17475.
-
(1995)
J Biol Chem
, vol.270
, pp. 17468-17475
-
-
Wong, S.C.1
Proefke, S.A.2
Bhushan, A.3
Matherly, L.H.4
-
8
-
-
0027963626
-
Isolation of a hamster cDNA clone coding for a function involved in methotrexate uptake
-
Williams FMR, Murray RC, Underhill TM, Flintoff WF. Isolation of a hamster cDNA clone coding for a function involved in methotrexate uptake. J Biol Chem. 269:1994;5810-5816.
-
(1994)
J Biol Chem
, vol.269
, pp. 5810-5816
-
-
Williams, F.M.R.1
Murray, R.C.2
Underhill, T.M.3
Flintoff, W.F.4
-
9
-
-
0028887425
-
Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake
-
Williams FMR, Flintoff WF. Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake. J Biol Chem. 270:1995;2987-2992.
-
(1995)
J Biol Chem
, vol.270
, pp. 2987-2992
-
-
Williams, F.M.R.1
Flintoff, W.F.2
-
11
-
-
0015246387
-
The characteristics of the membrane transport of amethopterin and the naturally occurring folates
-
Goldman ID. The characteristics of the membrane transport of amethopterin and the naturally occurring folates. Ann NY Acad Sci. 186:1971;400-422.
-
(1971)
Ann NY Acad Sci
, vol.186
, pp. 400-422
-
-
Goldman, I.D.1
-
12
-
-
0021152014
-
Interaction between anions and the reduced folate/methotrexate transport system in L1210 cell plasma membrane vesicles: Directional symmetry and anion specificity for differential mobility of loaded and unloaded carrier
-
Yang C-H, Sirotnak FM, Dembo M. Interaction between anions and the reduced folate/methotrexate transport system in L1210 cell plasma membrane vesicles Directional symmetry and anion specificity for differential mobility of loaded and unloaded carrier . J Membr Biol. 79:1984;285-292.
-
(1984)
J Membr Biol
, vol.79
, pp. 285-292
-
-
Yang C-H1
Sirotnak, F.M.2
Dembo, M.3
-
13
-
-
0020957864
-
Structural requirements for anion substrates of the methotrexate transport system of L1210 cells
-
Henderson GB, Zevely EM. Structural requirements for anion substrates of the methotrexate transport system of L1210 cells. Arch Biochem Biophys. 221:1983;438-446.
-
(1983)
Arch Biochem Biophys
, vol.221
, pp. 438-446
-
-
Henderson, G.B.1
Zevely, E.M.2
-
14
-
-
0019851443
-
Anion exchange mechanism for transport of methotrexate in L1210 cells
-
Henderson GB, Zevely EM. Anion exchange mechanism for transport of methotrexate in L1210 cells. Biochem Biophys Res Commun. 99:1981;163-169.
-
(1981)
Biochem Biophys Res Commun
, vol.99
, pp. 163-169
-
-
Henderson, G.B.1
Zevely, E.M.2
-
15
-
-
0020025052
-
Intracellular phosphate and its possible role as an exchange anion for active transport of methotrexate in L1210 cells
-
Henderson GB, Zevely EM. Intracellular phosphate and its possible role as an exchange anion for active transport of methotrexate in L1210 cells. Biochem Biophys Res Commun. 104:1982;474-482.
-
(1982)
Biochem Biophys Res Commun
, vol.104
, pp. 474-482
-
-
Henderson, G.B.1
Zevely, E.M.2
-
16
-
-
0025952140
-
Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement
-
Brigle KE, Westin EH, Houghton MT, Goldman ID. Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement. J Biol Chem. 266:1991;17243-17249.
-
(1991)
J Biol Chem
, vol.266
, pp. 17243-17249
-
-
Brigle, K.E.1
Westin, E.H.2
Houghton, M.T.3
Goldman, I.D.4
-
17
-
-
0028986856
-
Distinguishing between folate receptor-α-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells
-
Spinella MJ, Brigle KE, Sierra EE, Goldman ID. Distinguishing between folate receptor-α-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells. J Biol Chem. 270:1995;7842-7849.
-
(1995)
J Biol Chem
, vol.270
, pp. 7842-7849
-
-
Spinella, M.J.1
Brigle, K.E.2
Sierra, E.E.3
Goldman, I.D.4
-
18
-
-
0026652116
-
The biological chemistry of folate receptors
-
Antony AC. The biological chemistry of folate receptors. Blood. 79:1992;2807-2820.
-
(1992)
Blood
, vol.79
, pp. 2807-2820
-
-
Antony, A.C.1
-
19
-
-
0023683407
-
Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles
-
Kamen BA, Wang M, Streckfuss AJ, Peryea X, Anderson RGW. Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles. J Biol Chem. 263:1988;13602-13609.
-
(1988)
J Biol Chem
, vol.263
, pp. 13602-13609
-
-
Kamen, B.A.1
Wang, M.2
Streckfuss, A.J.3
Peryea, X.4
Anderson, R.G.W.5
-
20
-
-
0025303751
-
The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway
-
Rothberg KG, Ying Y, Kolhouse JF, Kamen BA, Anderson RGW. The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway. J Cell Biol. 110:1990;637-649.
-
(1990)
J Cell Biol
, vol.110
, pp. 637-649
-
-
Rothberg, K.G.1
Ying, Y.2
Kolhouse, J.F.3
Kamen, B.A.4
Anderson, R.G.W.5
-
21
-
-
0025275523
-
Characteristics of a novel transport system for folate compounds in wild-type and methotrexate-resistant L1210 cells
-
Henderson GB, Strauss BP. Characteristics of a novel transport system for folate compounds in wild-type and methotrexate-resistant L1210 cells. Cancer Res. 50:1990;1709-1714.
-
(1990)
Cancer Res
, vol.50
, pp. 1709-1714
-
-
Henderson, G.B.1
Strauss, B.P.2
-
22
-
-
0031021010
-
PH dependence of methotrexate transport by the reduced folate carrier and the folate receptor in L1210 leukemia cells. Further evidence for a third route mediated at low pH
-
Sierra EE, Brigle KE, Spinella MJ, Goldman ID. pH dependence of methotrexate transport by the reduced folate carrier and the folate receptor in L1210 leukemia cells. Further evidence for a third route mediated at low pH. Biochem Pharmacol. 53:1997;223-231.
-
(1997)
Biochem Pharmacol
, vol.53
, pp. 223-231
-
-
Sierra, E.E.1
Brigle, K.E.2
Spinella, M.J.3
Goldman, I.D.4
-
23
-
-
0014690663
-
Transport energetics of the folic acid analogue, methotrexate, in L1210 cells: Enhanced accumulation by metabolic inhibitors
-
Goldman ID. Transport energetics of the folic acid analogue, methotrexate, in L1210 cells Enhanced accumulation by metabolic inhibitors . J Biol Chem. 244:1969;3779-3785.
-
(1969)
J Biol Chem
, vol.244
, pp. 3779-3785
-
-
Goldman, I.D.1
-
24
-
-
0026761157
-
Separation and inhibitor specificity of a second unidirectional efflux route for methotrexate in L1210 cells
-
Henderson GB. Separation and inhibitor specificity of a second unidirectional efflux route for methotrexate in L1210 cells. Biochim Biophys Acta. 1110:1992;137-143.
-
(1992)
Biochim Biophys Acta
, vol.1110
, pp. 137-143
-
-
Henderson, G.B.1
-
25
-
-
0026741788
-
Energy-dependent efflux of methotrexate in L1210 leukemia cells. Evidence for the role of an ATPase obtained with inside-out plasma membrane vesicles
-
Schlemmer SR, Sirotnak FM. Energy-dependent efflux of methotrexate in L1210 leukemia cells. Evidence for the role of an ATPase obtained with inside-out plasma membrane vesicles. J Biol Chem. 267:1992;14746-14752.
-
(1992)
J Biol Chem
, vol.267
, pp. 14746-14752
-
-
Schlemmer, S.R.1
Sirotnak, F.M.2
-
26
-
-
0030758278
-
Impact of overexpression of the reduced folate carrier (RFC1), an anion exchanger, on concentrative transport in murine L1210 leukemia cells
-
Zhao R, Seither R, Brigle KE, Sharina IG, Wang PJ, Goldman ID. Impact of overexpression of the reduced folate carrier (RFC1), an anion exchanger, on concentrative transport in murine L1210 leukemia cells. J Biol Chem. 272:1997;21207-21212.
-
(1997)
J Biol Chem
, vol.272
, pp. 21207-21212
-
-
Zhao, R.1
Seither, R.2
Brigle, K.E.3
Sharina, I.G.4
Wang, P.J.5
Goldman, I.D.6
-
27
-
-
0021720510
-
A novel class of genetic varients of the L1210 cell up-regulated for folate analogue transport inward
-
Sirotnak FM, Moccio DM, Yang C-H. A novel class of genetic varients of the L1210 cell up-regulated for folate analogue transport inward. J Biol Chem. 259:1984;13139-13144.
-
(1984)
J Biol Chem
, vol.259
, pp. 13139-13144
-
-
Sirotnak, F.M.1
Moccio, D.M.2
Yang C-H3
-
28
-
-
0025016121
-
Methotrexate transport in variant human CCRF-CEM leukemia cells with elevated levels of the reduced folate carrier. Selective effect on carrier-mediated transport of physiological concentrations of reduced folates
-
Jansen G, Westerhof GR, Jarmuszewski MJA, Kathmann I, Rijksen G, Schornagel JH. Methotrexate transport in variant human CCRF-CEM leukemia cells with elevated levels of the reduced folate carrier. Selective effect on carrier-mediated transport of physiological concentrations of reduced folates. J Biol Chem. 265:1990;18272-18277.
-
(1990)
J Biol Chem
, vol.265
, pp. 18272-18277
-
-
Jansen, G.1
Westerhof, G.R.2
Jarmuszewski, M.J.A.3
Kathmann, I.4
Rijksen, G.5
Schornagel, J.H.6
-
29
-
-
0026075874
-
Identification of a highly glycosylated methotrexate membrane carrier in K562 human erythroleukemia cells up-regulated for tetrahydrofolate cofactor and methotrexate transport
-
Matherly LH, Czajkowski CA, Angeles SM. Identification of a highly glycosylated methotrexate membrane carrier in K562 human erythroleukemia cells up-regulated for tetrahydrofolate cofactor and methotrexate transport. Cancer Res. 51:1991;3420-3426.
-
(1991)
Cancer Res
, vol.51
, pp. 3420-3426
-
-
Matherly, L.H.1
Czajkowski, C.A.2
Angeles, S.M.3
-
30
-
-
0018079661
-
Establishment and characterization of three new continuous cell lines derived from human breast carcinomas
-
Engel LW, Young NA, Tralka TS, Lippman ME, O'Brien SJ, Joyce MJ. Establishment and characterization of three new continuous cell lines derived from human breast carcinomas. Cancer Res. 38:1978;3352-3364.
-
(1978)
Cancer Res
, vol.38
, pp. 3352-3364
-
-
Engel, L.W.1
Young, N.A.2
Tralka, T.S.3
Lippman, M.E.4
O'Brien, S.J.5
Joyce, M.J.6
-
31
-
-
0021209446
-
A methotrexate-resistant human breast cancer cell line with multiple defects, including diminished formation of methotrexate polyglutamates
-
Cowan KH, Jolivet J. A methotrexate-resistant human breast cancer cell line with multiple defects, including diminished formation of methotrexate polyglutamates. J Biol Chem. 259:1984;10793-10800.
-
(1984)
J Biol Chem
, vol.259
, pp. 10793-10800
-
-
Cowan, K.H.1
Jolivet, J.2
-
32
-
-
0008195538
-
Comparison of methotrexate polyglutamylation in L1210 leukemia cells when influx is mediated by the reduced folate carrier or the folate receptor. Lack of evidence for influx route-specific effects
-
Spinella MJ, Brigle KE, Freemantle SJ, Sierra EE, Goldman ID. Comparison of methotrexate polyglutamylation in L1210 leukemia cells when influx is mediated by the reduced folate carrier or the folate receptor. Lack of evidence for influx route-specific effects. Biochem Pharmacol. 52:1996;703-712.
-
(1996)
Biochem Pharmacol
, vol.52
, pp. 703-712
-
-
Spinella, M.J.1
Brigle, K.E.2
Freemantle, S.J.3
Sierra, E.E.4
Goldman, I.D.5
-
33
-
-
0000218191
-
Purification and properties of dihydrofolate reductase from Ehrlich ascites carcinoma cells
-
Bertino JR, Perkins JP, Johns DG. Purification and properties of dihydrofolate reductase from Ehrlich ascites carcinoma cells. Biochemistry. 4:1965;839-846.
-
(1965)
Biochemistry
, vol.4
, pp. 839-846
-
-
Bertino, J.R.1
Perkins, J.P.2
Johns, D.G.3
-
35
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, Vistica D, Warren JT, Bokesch H, Kenney S, Boyd MR. New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst. 82:1990;1107-1112.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
Warren, J.T.7
Bokesch, H.8
Kenney, S.9
Boyd, M.R.10
-
36
-
-
0028111514
-
Increased expression and genomic organization of a folate-binding protein homologous to the human placental isoform in L1210 murine leukemia cells with a defective reduced folate carrier
-
Brigle KE, Seither RL, Westin EH, Goldman ID. Increased expression and genomic organization of a folate-binding protein homologous to the human placental isoform in L1210 murine leukemia cells with a defective reduced folate carrier. J Biol Chem. 269:1994;4267-4272.
-
(1994)
J Biol Chem
, vol.269
, pp. 4267-4272
-
-
Brigle, K.E.1
Seither, R.L.2
Westin, E.H.3
Goldman, I.D.4
-
37
-
-
0020081481
-
Rapid formation of poly-γ-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro
-
Fry DW, Yalowich JC, Goldman ID. Rapid formation of poly-γ-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro. J Biol Chem. 257:1982;1890-1896.
-
(1982)
J Biol Chem
, vol.257
, pp. 1890-1896
-
-
Fry, D.W.1
Yalowich, J.C.2
Goldman, I.D.3
-
38
-
-
0031012198
-
Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity
-
Wong SC, McQuade R, Proefke SA, Bhushan A, Matherly LH. Human K562 transfectants expressing high levels of reduced folate carrier but exhibiting low transport activity. Biochem Pharmacol. 53:1997;199-206.
-
(1997)
Biochem Pharmacol
, vol.53
, pp. 199-206
-
-
Wong, S.C.1
McQuade, R.2
Proefke, S.A.3
Bhushan, A.4
Matherly, L.H.5
-
39
-
-
0026403582
-
Folate transport and the modulation of antifolate sensitivity in a methotrexate-resistant human breast cancer cell line
-
Dixon KH, Trepel JB, Eng SC, Cowan KH. Folate transport and the modulation of antifolate sensitivity in a methotrexate-resistant human breast cancer cell line. Cancer Commun. 3:1991;357-365.
-
(1991)
Cancer Commun
, vol.3
, pp. 357-365
-
-
Dixon, K.H.1
Trepel, J.B.2
Eng, S.C.3
Cowan, K.H.4
|