Comparison of methotrexate polyglutamylation in L1210 leukemia cells when influx is mediated by the reduced folate carrier or the folate receptor. Lack of evidence for influx route-specific effects

Biochemical Pharmacology

Volumn 52, Issue 5, 1996, Pages 703-712

  Spinella, Michael J ^b   Brigle, Kevin E ^b   Freemantle, Sarah J ^b   Sierra, Esteban E ^b   Goldman, I David ^a,b  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

folate receptor; L1210; methotrexate; polyglutamylation; reduced folate carrier; transport

Indexed keywords

DIHYDROFOLATE REDUCTASE; FOLATE BINDING PROTEIN; METHOTREXATE; METHOTREXATE POLYGLUTAMATE; TRIMETREXATE;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG METABOLISM; GENETIC TRANSFECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LEUKEMIA L 1210; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0008195538     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00347-4     Document Type: Article

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