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Volumn 280, Issue 5366, 1998, Pages 1073-1077

Genetic evaluation of suspected cases of transient HIV-1 infection of infants

(29)  Frenkel, Lisa M a,b   Mullins, James I c   Learn, Gerald H c   Manns Arcuino, Laura b   Herring, Belinda L c   Kalish, Marcia L d   Steketee, Richard W d   Thea, Donald M e   Nichols, Joan E a,f   Liu, Shan Lu c   Harmache, Abdallah c   He, Xi c   Muthui, David c   Madan, Anup c   Hood, Leroy c   Haase, Ashley T g   Zupancic, Mary g   Staskus, Katherine g   Wolinsky, Steven h   Krogstad, Paul i   more..


Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; INFANT; INFANT DISEASE; NEWBORN; NUCLEOTIDE SEQUENCE; PATIENT SATISFACTION; PERINATAL CARE; PHYLOGENY; PRIORITY JOURNAL; VIRUS DETECTION;

EID: 0032524738     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.280.5366.1073     Document Type: Article
Times cited : (56)

References (33)
  • 4
    • 0025093906 scopus 로고
    • W. Borkowsky, K. Krasinski, T. Moore, V. Papaevangelou, AIDS Res. Hum. Retroviruses 6, 673 (1990); M. Clerici et al., J. Infect. Dis. 165, 1012 (1992); R. Cheynier et al., Eur. J. Immunol. 22, 2211 (1992); M. Clerici et al., AIDS 7, 1427 (1993); S. L. Rowland-Jones et al., Lancet 341, 860 (1993); S. L. Rowland-Jones et al., Nature Med. 1, 59 (1995); M. Clerici et al., JAMA 271, 42 (1994); A. De Maria, C. Cirillo, L. Moretta, J. Infect. Dis. 170, 1296 (1994).
    • (1990) AIDS Res. Hum. Retroviruses , vol.6 , pp. 673
    • Borkowsky, W.1    Krasinski, K.2    Moore, T.3    Papaevangelou, V.4
  • 5
    • 0026534763 scopus 로고
    • W. Borkowsky, K. Krasinski, T. Moore, V. Papaevangelou, AIDS Res. Hum. Retroviruses 6, 673 (1990); M. Clerici et al., J. Infect. Dis. 165, 1012 (1992); R. Cheynier et al., Eur. J. Immunol. 22, 2211 (1992); M. Clerici et al., AIDS 7, 1427 (1993); S. L. Rowland-Jones et al., Lancet 341, 860 (1993); S. L. Rowland-Jones et al., Nature Med. 1, 59 (1995); M. Clerici et al., JAMA 271, 42 (1994); A. De Maria, C. Cirillo, L. Moretta, J. Infect. Dis. 170, 1296 (1994).
    • (1992) J. Infect. Dis. , vol.165 , pp. 1012
    • Clerici, M.1
  • 6
    • 0026746352 scopus 로고
    • W. Borkowsky, K. Krasinski, T. Moore, V. Papaevangelou, AIDS Res. Hum. Retroviruses 6, 673 (1990); M. Clerici et al., J. Infect. Dis. 165, 1012 (1992); R. Cheynier et al., Eur. J. Immunol. 22, 2211 (1992); M. Clerici et al., AIDS 7, 1427 (1993); S. L. Rowland-Jones et al., Lancet 341, 860 (1993); S. L. Rowland-Jones et al., Nature Med. 1, 59 (1995); M. Clerici et al., JAMA 271, 42 (1994); A. De Maria, C. Cirillo, L. Moretta, J. Infect. Dis. 170, 1296 (1994).
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2211
    • Cheynier, R.1
  • 7
    • 0027359267 scopus 로고
    • W. Borkowsky, K. Krasinski, T. Moore, V. Papaevangelou, AIDS Res. Hum. Retroviruses 6, 673 (1990); M. Clerici et al., J. Infect. Dis. 165, 1012 (1992); R. Cheynier et al., Eur. J. Immunol. 22, 2211 (1992); M. Clerici et al., AIDS 7, 1427 (1993); S. L. Rowland-Jones et al., Lancet 341, 860 (1993); S. L. Rowland-Jones et al., Nature Med. 1, 59 (1995); M. Clerici et al., JAMA 271, 42 (1994); A. De Maria, C. Cirillo, L. Moretta, J. Infect. Dis. 170, 1296 (1994).
    • (1993) AIDS , vol.7 , pp. 1427
    • Clerici, M.1
  • 8
    • 0027478866 scopus 로고
    • W. Borkowsky, K. Krasinski, T. Moore, V. Papaevangelou, AIDS Res. Hum. Retroviruses 6, 673 (1990); M. Clerici et al., J. Infect. Dis. 165, 1012 (1992); R. Cheynier et al., Eur. J. Immunol. 22, 2211 (1992); M. Clerici et al., AIDS 7, 1427 (1993); S. L. Rowland-Jones et al., Lancet 341, 860 (1993); S. L. Rowland-Jones et al., Nature Med. 1, 59 (1995); M. Clerici et al., JAMA 271, 42 (1994); A. De Maria, C. Cirillo, L. Moretta, J. Infect. Dis. 170, 1296 (1994).
    • (1993) Lancet , vol.341 , pp. 860
    • Rowland-Jones, S.L.1
  • 9
    • 0028944192 scopus 로고
    • W. Borkowsky, K. Krasinski, T. Moore, V. Papaevangelou, AIDS Res. Hum. Retroviruses 6, 673 (1990); M. Clerici et al., J. Infect. Dis. 165, 1012 (1992); R. Cheynier et al., Eur. J. Immunol. 22, 2211 (1992); M. Clerici et al., AIDS 7, 1427 (1993); S. L. Rowland-Jones et al., Lancet 341, 860 (1993); S. L. Rowland-Jones et al., Nature Med. 1, 59 (1995); M. Clerici et al., JAMA 271, 42 (1994); A. De Maria, C. Cirillo, L. Moretta, J. Infect. Dis. 170, 1296 (1994).
    • (1995) Nature Med. , vol.1 , pp. 59
    • Rowland-Jones, S.L.1
  • 10
    • 0027972391 scopus 로고
    • W. Borkowsky, K. Krasinski, T. Moore, V. Papaevangelou, AIDS Res. Hum. Retroviruses 6, 673 (1990); M. Clerici et al., J. Infect. Dis. 165, 1012 (1992); R. Cheynier et al., Eur. J. Immunol. 22, 2211 (1992); M. Clerici et al., AIDS 7, 1427 (1993); S. L. Rowland-Jones et al., Lancet 341, 860 (1993); S. L. Rowland-Jones et al., Nature Med. 1, 59 (1995); M. Clerici et al., JAMA 271, 42 (1994); A. De Maria, C. Cirillo, L. Moretta, J. Infect. Dis. 170, 1296 (1994).
    • (1994) JAMA , vol.271 , pp. 42
    • Clerici, M.1
  • 11
    • 0027973482 scopus 로고
    • W. Borkowsky, K. Krasinski, T. Moore, V. Papaevangelou, AIDS Res. Hum. Retroviruses 6, 673 (1990); M. Clerici et al., J. Infect. Dis. 165, 1012 (1992); R. Cheynier et al., Eur. J. Immunol. 22, 2211 (1992); M. Clerici et al., AIDS 7, 1427 (1993); S. L. Rowland-Jones et al., Lancet 341, 860 (1993); S. L. Rowland-Jones et al., Nature Med. 1, 59 (1995); M. Clerici et al., JAMA 271, 42 (1994); A. De Maria, C. Cirillo, L. Moretta, J. Infect. Dis. 170, 1296 (1994).
    • (1994) J. Infect. Dis. , vol.170 , pp. 1296
    • De Maria, A.1    Cirillo, C.2    Moretta, L.3
  • 12
    • 0029007690 scopus 로고
    • M. O. McClure et al., Nature 375, 637 (1995).
    • (1995) Nature , vol.375 , pp. 637
    • McClure, M.O.1
  • 15
    • 16944362073 scopus 로고    scopus 로고
    • Y. Cao et al., Nature Med. 3, 549 (1997).
    • (1997) Nature Med. , vol.3 , pp. 549
    • Cao, Y.1
  • 16
    • 0029034124 scopus 로고
    • L. M. Frenkel et al., Clin. Infect. Dis. 20, 1321 (1995). Reaction conditions plus a detailed list of PCR primers covering the gag, pol, and env regions used for assessing HIV-1 infection are provided in (12). For phylogenetic analysis, a 650-base pair (bp) region of HIV-1 env, corresponding to the V3 through V5 region, was amplified by nPCR with primers ED5/12 and ES7/8 [E. L. Delwart et al., Science 262, 1257 (1993)] and cloned into plasmids. Four to six clones from each specimen were sequenced. In the case of the CDC specimens, direct sequencing of 345 bp of the V3 and flanking regions was done as previously described [H. W. Jaffe et al., Ann. Intern. Med. 121, 855 (1994)].
    • (1995) Clin. Infect. Dis. , vol.20 , pp. 1321
    • Frenkel, L.M.1
  • 17
    • 0027690383 scopus 로고
    • L. M. Frenkel et al., Clin. Infect. Dis. 20, 1321 (1995). Reaction conditions plus a detailed list of PCR primers covering the gag, pol, and env regions used for assessing HIV-1 infection are provided in (12). For phylogenetic analysis, a 650-base pair (bp) region of HIV-1 env, corresponding to the V3 through V5 region, was amplified by nPCR with primers ED5/12 and ES7/8 [E. L. Delwart et al., Science 262, 1257 (1993)] and cloned into plasmids. Four to six clones from each specimen were sequenced. In the case of the CDC specimens, direct sequencing of 345 bp of the V3 and flanking regions was done as previously described [H. W. Jaffe et al., Ann. Intern. Med. 121, 855 (1994)].
    • (1993) Science , vol.262 , pp. 1257
    • Delwart, E.L.1
  • 18
    • 0028604415 scopus 로고
    • L. M. Frenkel et al., Clin. Infect. Dis. 20, 1321 (1995). Reaction conditions plus a detailed list of PCR primers covering the gag, pol, and env regions used for assessing HIV-1 infection are provided in (12). For phylogenetic analysis, a 650-base pair (bp) region of HIV-1 env, corresponding to the V3 through V5 region, was amplified by nPCR with primers ED5/12 and ES7/8 [E. L. Delwart et al., Science 262, 1257 (1993)] and cloned into plasmids. Four to six clones from each specimen were sequenced. In the case of the CDC specimens, direct sequencing of 345 bp of the V3 and flanking regions was done as previously described [H. W. Jaffe et al., Ann. Intern. Med. 121, 855 (1994)].
    • (1994) Ann. Intern. Med. , vol.121 , pp. 855
    • Jaffe, H.W.1
  • 19
    • 2642628298 scopus 로고    scopus 로고
    • note
    • Independently segregating loci or the HLA-DQa locus were used to evaluate the identity of patient specimens. The former included HLA-DQA1, low-density lipoprotein receptor, glycophorin A, hemoglobin G gammaglobin, D7S8, and a group-specific component (GC) (AmpliType PM PCR Amplification and Typing Kit, Perkin-Elmer, Foster City, CA). The combined power of discrimination for these six markers for Caucasians in the United States is 0.9997. Discordance of the HLA-DQA1 loci (Amplitype HLA DQa Amplification and Typing Kit, Perkin-Elmer) among the CDC infant's specimens was taken to indicate specimen mislabeling. When an infant's specimens had concordant HLA-DQa loci, the env sequences in each specimen were examined by phylogenetic analysis.
  • 20
    • 8944249298 scopus 로고    scopus 로고
    • The methods described by G. H. Learn et al. [J. Virol. 70, 5720 (1996)] were used to align DNA sequences (with the use of CLUSTALW plus manual adjustment), calculate genetic distances (with the use of DNADIST, using the maximum likelihood method), evaluate potential sample mixups, construct neighbor joining trees, and perform bootstrap analyses (1000 replicates). Sequence regions that could not be unambiguously aligned were removed from subsequent analyses. Each sequence was compared for phylogenetic relatedness to the entire set of published and available unpublished laboratory HIV database sequences. If after this analysis the viral sequences from a mother and an infant appeared as a monophyletic group on a phylogenetic tree, they were judged to be phylogenetically linked or to have a common ancestor not shared by sequences from any other individuals evaluated. Issues regarding the assignment of phylogenetic linkage are discussed in greater detail by Learn et al.
    • (1996) J. Virol. , vol.70 , pp. 5720
    • Learn, G.H.1
  • 21
    • 2642592594 scopus 로고    scopus 로고
    • L. M. Frenkel et al., at www.sciencemag.org/feature/ data/974996.shl.
    • Frenkel, L.M.1
  • 22
    • 15844388931 scopus 로고    scopus 로고
    • R. Liu et al., Cell 86, 367 (1996).
    • (1996) Cell , vol.86 , pp. 367
    • Liu, R.1
  • 23
    • 2642603810 scopus 로고    scopus 로고
    • unpublished data
    • L. M. Frenkel et al., unpublished data.
    • Frenkel, L.M.1
  • 24
    • 13344294366 scopus 로고    scopus 로고
    • M.-L. Newell et al., Lancet 347, 213 (1996).
    • (1996) Lancet , vol.347 , pp. 213
    • Newell, M.-L.1
  • 28
    • 0028937941 scopus 로고
    • T. Liu et al., J. Immunol. 154, 3147 (1995).
    • (1995) J. Immunol. , vol.154 , pp. 3147
    • Liu, T.1
  • 32
  • 33
    • 2642595643 scopus 로고    scopus 로고
    • note
    • We thank J. Conroy for performing PCR assays; E. Abrams, M. S. Ortoff, R. C. Reichman, L. M. Demeter, J. S. Lambert, R. Dolin, R. Sperling, D. Shapiro, G. McSherry, and the Ariel Project and ACTG 076 investigators for critical patient specimens; D. Swofford for use of computer program PAUP*, version 4.0.0d63; and C. B. Wilson and K. K. Holmes for editorial contributions. This work was supported by grants from the Pediatric AIDS Foundation (500153-10-PGT, 50366-14-PGR, 55516-ARI, 55529-ARI, 55525-ARI, 55532-ARI, 55526-ARI, 55531-ARI, and 55522-ARI), the U.S. Public Health Service (UO1-27658, Al32910, Al27757, and Al35539), and the Foster Foundation.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.