A chloroquine resistance locus in the rodent malaria parasite Plasmodium chabaudi

Molecular and Biochemical Parasitology

Volumn 93, Issue 1, 1998, Pages

  Carlton, Jane ^a,b   Mackinnon, Margaret ^a   Walliker, David ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b University of Florida College of Veterinary Medicine   (United States)

Author keywords

Chloroquine; Plasmodium chabaudi; Resistance

Indexed keywords

CHLOROQUINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHROMOSOME 11; DRUG RESISTANCE; GENE LOCUS; GENETIC LINKAGE; GENETIC POLYMORPHISM; MALE; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PLASMODIUM CHABAUDI; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ANIMALS; ANTIMALARIALS; CHLOROQUINE; CHROMOSOME MAPPING; CROSSES, GENETIC; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; GENES, PROTOZOAN; GENETIC MARKERS; HSP90 HEAT-SHOCK PROTEINS; LINKAGE (GENETICS); MALE; MEIOSIS; MICE; PLASMODIUM CHABAUDI; RATS;

PLASMODIUM CHABAUDI; PLASMODIUM FALCIPARUM; RODENTIA;

EID: 0032523984     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(98)00021-8     Document Type: Article

References (71)

1. [1] Harinasuta T, Migasen S, Bunnag D. Chloroquine resistance in Plasmodium falciparum in Thailand. UNESCO First Regional Symposium on Scientific Knowledge of Tropical Parasites. Singapore: University of Singapore, 1962:148-53.
2. [2] Young MD, Moore DV. Chloroquine resistance in Plasmodium falciparum. Am J Trop Med Hyg 1961;10:317-20.
3. [3] Cowman AF, Foote SJ. Chemotherapy and drug resistance in malaria. Int J Parasitol 1990;20:503-13.
4. [4] Walliker D. The role of molecular genetics in field studies on malaria parasites. Int J Parasitol 1994;24:799-808.
5. [5] Foote SJ, Thompson JK, Cowman AF, Kemp DJ. Amplification of the multi-drug resistance gene in some chloroquine-resistant isolates of P. falciparum. Cell 1989;57:921-30.
6. [6] Wilson CM, Serrano AE, Wasley A, Bogenschutz MP, Shankar AH, Wirth DF. Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum. Science 1989;244:1184-6.
7. [7] Gottesman MM, Pastan I, Ambudkar SV. P-glycoprotein and multidrug resistance. Curr Opin Gen Dev 1996;6:610-7.
8. [8] Krogstad DJ, Gluzman IY, Kyle DE, Oduola AMJ, Martin SK, Milhous WK, Schlesinger PH. Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance. Science 1987;238:1283-5.
9. [9] Foote SJ, Kyle DE, Martin RK, Oduola AM, Forsyth K, Kemp DJ, Cowman AF. Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature 1990;345: 255-8.
10. [10] Haruki K, Bray PG, Ward SA, Hommel M, Ritchie GY. Chloroquine resistance of Plasmodium falciparum: further evidence for a lack of association with mutations of the pfmdr1 gene. Trans R Soc Trop Med Hyg 1994;88:694.
11. [11] Adagu IS, Warhurst DC, Carucci DJ, Duraisingh MT. Pfmdr1 mutations and chloroquine resistance in Plasmodium falciparum isolates from Zaria, Nigeria. Trans R Soc Trop Med Hyg 1995;89:132-9.
12. [12] Awad-El-Kariem FM, Miles MA, Warhurst DC. Chloroquine-resistant Plasmodium falciparum isolates from the Sudan lack two mutations in the pfmdr1 gene thought to be associated with chloroquine resistance. Trans R Soc Trop Med Hyg 1992;86:587-9.
13. [13] Wilson CM, Volkman SK, Thaithong S, Martin RK, Kyle DE, Milhous WK, Wirth DF. Amplification of pfmdr-1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand. Mol Biochem Parasitol 1993;57:151-60.
14. [14] Wellems TE, Panton LJ, Gluzman IY, Rosario VE, Gwadz RW, Walker-Jonah A, Krogstad DJ. Chloroquine-resistance not linked to mdr-like genes in a Plasmodium falciparum cross. Nature 1990;345:253-5.
15. [15] Wellems TE, Walker-Jonah A, Panton LJ. Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7. Proc Natl Acad Sci USA 1991;88:3382-6.
16. [16] Su X, Wellems TE. Sequence, transcript characterisation and polymorphisms of a Plasmodium falciparum gene belonging to the heat-shock protein (HSP) 90 family. Gene 1994;151:225-30.
17. [17] Su X-Z, Kirkman LA, Fujioka H, Wellems TE. Complex polymorphisms in an ∼ 330 kDa protein are linked to chloroquine-resistant P. falciparum in south-east Asia and Africa. Cell 1997;91:593-603.
18. [18] Rosario VE. Genetics of chloroquine resistance in malaria parasites. Nature 1976;261:585-6.
19. [19] Padua RA. Plasmodium chabaudi: genetics of resistance to chloroquine. Exp Parasitol 1981;52:419-26.
20. [20] Walliker D, Carter R, Morgan S. Genetic recombination in Plasmodium berghei. Parasitology 1973;66:309-20.
21. [21] Cornelissen AWCA, Walliker D. Gametocyte development of Plasmodium chabaudi in mice and rats: evidence for host induction of gametocytogenesis. Parasitol Res 1985;71:297-303.
22. [22] Walliker D, Carter R, Sanderson A. Genetic studies on Plasmodium chabaudi: recombination between enzyme markers. Parasitology 1975;70:19-24.
23. [23] Lainson FA. Observations on the morphology and electrophoretic variation of enzymes of the rodent malaria parasites of Cameroon, P. yoelii, P. chabaudi and P. vinckei. Parasitology 1983;86:221-9.
24. [24] Snounou G, Viriyakosol S, Holmquist G, Berzins K, Perlmann P, Brown KN. Cloning of genomic fragment from Plasmodium chabaudi expressing a 105 kilodalton antigen epitope. Mol Biochem Parasitol 1988;28:153-62.
25. [25] Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. New York: Cold Spring Harbour Laboratory, 1989.
26. [26] Carlton JM-R, Howard J, Jensen JB, Walliker D. A rapid technique for the detection of DNA polymorphisms in Plasmodium. Exp Parasitol 1995;80:163-6.
27. [27] Bafort J. Primary exo-erythrocytic forms of Plasmodium vinckei. Nature 1968;217:1264-5.
28. [28] Bhasin VK, Trager W. Gametocyte-forming and non-gametocyte-forming clones of Plasmodium falciparum. Am J Trop Med Hyg 1984;33:534-7.
29. [29] Janse CJ, Carlton JM-R, Walliker D, Waters AP. Conserved location of genes on polymorphic chromosomes of four species of malaria parasites. Mol Biochem Parasitol 1994;68:285-96.
30. [30] J. Carlton. The genetics of chloroquine resistance in the rodent malaria parasite Plasmodium chabaudi, PhD Thesis. UK: University of Edinburgh, 1995.
31. [31] Green P, Falls K, Crooks S. Documentation for CRI-MAP Version 2.4. 1990, Washington University School of Medicine, St. Louis, MO, USA.
32. [32] Ott J. Analysis of human genetic linkage. Baltimore, MD: Johns Hopkins Press, 1985.
33. [33] Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 1995;11:241-7.
34. [34] Rubio JP, Cowman AF. The ATP-binding cassette (ABC) gene family of Plasmodium falciparum. Parasitol Today 1996;12:135-40.
35. [35] Cowman AF, Karcz S, Galatis D, Culvenor JG. A P-glycoprotein homologue of Plasmodium falciparum is localised on the digestive vacuole. J Cell Biol 1991;113:1033-42.
36. [36] Peel SA, Bright P, Yount B, Handy J, Baric RS. A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr1) of Plasmodium falciparum in vitro. Am J Trop Med Hyg 1994;51:648-58.
37. [37] Barnes DA, Foote SJ, Galatis D, Kemp DJ, Cowman AF. Selection for high level chloroquine resistance results in deamplification of the pfmdr-1 gene and increased sensitivity to mefloquine in Plasmodium falciparum. EMBO J 1992;11:3067-75.
38. [38] Cowman AF, Galatis D, Thompson JK. Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr-1 gene and cross-resistance to halofantrine and quinine. Proc Natl Acad Sci USA 1994;91:1143-7.
39. [39] Cremer G, Basco LK, Le Bras JL, Camus D, Slomianny C. Plasmodium falciparum: Detection of P-glycoprotein in chloroquine-susceptible and chloroquine-resistant clones and isolates. Exp Parasitol 1995; 81:1-8.
40. [40] van Es HHG, Karcz S, Chu F, Cowman AF, Vidal S, Gros P, Schurr E. Expression of the plasmodial pfmdr1 gene in mammalian cells is associated with increased susceptibility to chloroquine. Mol Cell Biol 1994; 14:2419-28.
41. [41] Basco LK, de Pecoulas PE, Le Bras J, Wilson CM. Plasmodium falciparum: molecular characterisation of multidrug-resistant Cambodian isolates. Exp Parasitol 1992;82:97-103.
42. 2+ antagonists on chloroquine-resistant and chloroquine-sensitive parasites. Exp Parasitol 1990;70:419-26.
43. [43] Ohsawa K, Tanabe K, Kimata I, Miki A. Ultrastructural changes associated with reversal of chloroquine resistance by verapamil in Plasmodium chabaudi. Parasitology 1991;103:185-9.
44. 2+ modulators in resistant parasites. Exp Parasitol 1992;74:134-42.
45. [45] Walker-Jonah A, Dolan SA, Gwadz RW, Panton LJ, Wellems TE. An RFLP map of the Plasmodium falciparum genome, recombination rates and favored linkage groups in a genetic cross. Mol Biochem Parasitol 1992;51:313-20.
46. [46] Lander ES, Botstein D. Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 1989;121:185-99.
47. [47] van Dijk MR, Janse CJ, Waters AP. Expression of a Plasmodium gene introduced into subtelomeric regions of Plasmodium berghei chromosomes. Science 1996;271: 662-5.
48. [48] Favaloro JM, Culvenor JG, Anders RF, Kemp DJ. A Plasmodium chabaudi antigen located in the parasitophorous vacuole membrane. Mol Biochem Parasitol 1993;62:263-70.
49. 2+-ATPase of rabbit skeletal muscle sarcoplasmic reticulum. J Cell Sci 1990;97:487-95.
50. [50] Holloway SP, Sims PFG, Delves CJ, Scaife JG, Hyde JE. Isolation of α-tubulin genes from the human malaria parasite, Plasmodium falciparum: sequence analysis of α-tubulin. Mol Microbiol 1989;3:1501-10.
51. [51] Holloway SP, Gerousis M, Delves CJ, Sims PFG, Scaife JG, Hyde JE. The tubulin genes of the human malaria paraite Plasmodium falciparum, their chromosomal location and sequence analysis of the α-tubulin II gene. Mol Biochem Parasitol 1990;43:257-70.
52. [52] Ridley R, White JH, McAleese BM, Goman M, Alano P, Vries Ed. DNA polymerase δ: gene sequences from Plasmodium falciparum indicate that this enzyme is more highly conserved than DNA polymerase a. Nucleic Acids Res 1991;19:6731-6.
53. [53] Pace T, Ponzi M, Dore E, Janse CJ, Mons B, Frontali C. Long insertions within telomeres contribute to chromosome-size polymorphism in Plasmodium berghei. Mol Cell Biol 1990;10:6759-64.
54. [54] Cowman AF, Lew A. Antifolate drug selection results in duplication and rearrangement of chromosome 7 in Plasmodium chabaudi. Mol Cell Biol 1989;9:5182-8.
55. [55] Deleersnijder W, Hendrix D, Bendahman N, Hanegreefs J, Brijs L, Hamers-Casterman C, Hamers R. Molecular cloning and sequence analysis of the gene encoding the major merozoite surface antigen of Plasmodium chabaudi chabaudi IP-PCI. Mol Biochem Parasitol 1990;43:231-44.
56. [56] Marshall VM, Peterson MG, Lew AM, Kemp DJ. Structure of the apical membrane antigen 1 (AMA-1) of Plasmodium chabaudi. Mol Biochem Parasitol 1989;37:281-4.
57. [57] Sultan AA, Richardson WA, Alano P, Arnot DE, Doerig C. Cloning and characterisation of a Plasmodium falciparum homologue of the Ran/TC4 signal transducing GTPase involved in cell cycle control. Mol Biochem Parasitol 1994;65:331-8.
58. [58] Shippen-Lentz D, Ray R, Scaife JG, Langsley G, Vezza AC. Characterisation and complete nucleotide sequence of a 5.8S ribosomal RNA gene from Plasmodium falciparum. Mol Biochem Parasitol 1988;22:223-31.
59. [59] Shippen-Lentz DE, Vezza AC. The three 5S rRNA genes from the human malaria parasite Plasmodium falciparum are linked. Mol Biochem Parasitol 1988;27:263-74.
60. [60] Sharkey A, Langsley G, Patarapotikul J, Mercereau-Puijalon O, McLean AP, Walliker D. Chromosome size variation in the malaria parasite of rodents, Plasmodium chabaudi. Mol Biochem Parasitol 1988;28:47-54.
61. [61] Silveira JF, Sibilli L, Brunet E, Mercereau-Puijalon O. Cloning of cDNAS that code for Plasmodium chabaudi antigens of the erythrocytic forms and cross-hybridise with P. falciparum. Mol Biochem Parasitol 1984;11:133-43.
62. [62] Karcz SR, Hermann VR, Trottein F, Cowman AF. Cloning and characterization of the vacuolar ATPase B subunit from Plasmodium falciparum. Mol Biochem Parasitol 1994;65:123-33.
63. [63] Meier B, Döbeli H, Certa U. Stage-specific expression of aldolase isoenzymes in the rodent malaria parasite Plasmodium berghei. Mol Biochem Parasitol 1992;52:15-28.
64. [64] Li WB, Bzik DJ, Tanaka M, Gu H, Fox BA, Inselburg J. Characterisation of the gene encoding the largest subunit of Plasmodium falciparum RNA polymerase III. Mol Biochem Parasitol 1991;46:229-40.
65. [65] O'Brien E, Kurdi-Haidar B, Wanachiwanawin W, Carvajal JL, Vulliamy TJ, Cappadoro M, Mason PJ, Luzzatto L. Cloning of the glucose 6-phosphate dehydrogenase gene from Plasmodium falciparum. Mol Biochem Parasitol 1994;64:313-26.
66. [66] Vinkenoog R, Veldhuisen B, Speranca MA, del Portillo HA, Janse CJ, Waters AP. Comparison of introns in a cdc2-homologous gene in a number of Plasmodium species. Mol Biochem Parasitol 1995;71:233-41.
67. [67] Kilbey B, Fraser I, McAleese S, Goman M, Ridley RG. Molecular characterisation and stage-specific expression of proliferating cell nuclear antigen (PCNA) from the malarial parasite, Plasmodium falciparum. Nucleic Acids Res 1993;21:239-43.
68. [68] Creedon KA, Kaslow DC, Rathod PK, Wellems TE. Identification of a Plasmodium falciparum histone 2A gene. Mol Biochem Parasitol 1992;54:113-6.
69. [69] McAndrew MB, Read M, Sims PFG, Hyde JE. Characterisation of the gene encoding an unusually divergent TATA-binding protein (TBP) from the extremely A + T-rich human malaria parasite Plasmodium falciparum. Gene 1993;124:165-71.
70. [70] Tosh K, Kilbey B. The gene encoding topoisomerase I from the human malaria parasite Plasmodium falciparum. Gene 1995;163:151-4.
71. [71] Carlton JM-R, Vinkenoog R, Waters AP, Walliker D. Gene synteny in species of Plasmodium. Mol Biochem Parasitol (in press).