Role of αIIbβ3 integrin in prostate cancer metastasis

Prostate

Volumn 35, Issue 3, 1998, Pages 185-192

  Trikha, Mohit ^a   Raso, Erzsebet ^b   Cai, Yinlong ^a   Fazakas, Zsolt ^b   Paku, Sandor ^b   Porter, Arthur T ^a,c   Timar, Jozsef ^b   Honn, Kenneth V ^a,c  

^a WAYNE STATE UNIVERSITY   (United States)

^b SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^c DETROIT MEDICAL CENTER   (United States)

Author keywords

DU 145; Ectopic; Immunofluorescence; Orthotopic; PC 3

Indexed keywords

FIBRONECTIN; INTEGRIN; FIBRINOGEN RECEPTOR; MONOCLONAL ANTIBODY;

ARTICLE; CARCINOGENESIS; CELL ADHESION; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; METASTASIS; NORTHERN BLOTTING; PRIORITY JOURNAL; PROSTATE CANCER; ADENOCARCINOMA; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; IN VITRO STUDY; LUNG TUMOR; MALE; METABOLISM; MOLECULAR GENETICS; MOUSE; MOUSE MUTANT; PATHOLOGY; PHENOTYPE; PHYSIOLOGY; PROSTATE TUMOR;

ADENOCARCINOMA; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, SCID; MOLECULAR SEQUENCE DATA; PHENOTYPE; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROSTATIC NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0032523232     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(19980515)35:3<185::AID-PROS4>3.0.CO;2-G     Document Type: Article

References (21)

1. Tang D, Honn KV: Adhesion molecules and tumor metastasis: An update. Invasion Metastasis 1994;95:109-122.
2. Varner JA, Cheresh DA: Integrins and cancer. Curr Opin Cell Biol 1996;8:724-730.
3. Hynes RO: Integrins: Versatility, modulation, and signaling in cell adhesion. Cell 1992;69:11-25.
4. Calvete JJ: Clues for understanding the structure and function of a prototypic human integrin: The platelet glycoprotein IIb/IIIa complex. Thromb Haemost 1994;72:1-15.
5. Ylanne JY, Hormia M, Jarvinen M, Virtanen I: Platelet glycoprotein IIb/IIIa complex in cultured cells. Localization in focal adhesion sites in spreading HEL cells. Blood 1988;72:1478-1486.
6. Chen YQ, Gao X, Timar J, Tang DG, Grossi IM, Chelladurai M, Kunicki TJ, Fliegel SEG, Taylor JD, Honn KV: Identification of the αIIbβ3 integrin in murine melanoma tumor cells. J Biol Chem 1992;267:17314-17320.
7. Trikha M, Timar J, Lundy SK, Szekeres K, Tang K, Grignon D, Porter AT, Honn KV: Human prostate carcinoma cells express functional αIIbβ3 integrin. Cancer Res 1996;56:5071-5078.
8. Chen YQ, Trikha M, Gao X, Bazaz R, Porter AT, Timar J, Honn KV: Ectopic expression of platelet integrin alpha IIb beta 3 in tumor cells from various species and histological origin. Int J Cancer 1997;72;642-648.
9. Trikha M, Timar J, Lundy SK, Szekeres K, Cai Y, Honn KV: The high affinity αIIbβ3 integrin is involved in invasion of human melanoma cells. Cancer Res 1997;57:2522-2528.
10. Kramer RH, Vu M, Cheng YF, Ramos DM: Integrin expression in malignant melanoma. Cancer Metastasis Rev 1991;10:49-59.
11. Rokhlin OW, Cohen MB: Expression of cellular adhesion molecules on human prostate tumor cell lines. Prostate 1995;26:205-212.
12. Knox JD, Cress AE, Clark V, Manriquez L, Affinito KT, Dalkin BL, Nagle RB: Differential expression of extracellular matrix molecules and the α6-integrins in the normal and neoplastic prostate. Am J Pathol 1994;145:167-174.
13. Shattil SJ, Hoxie JA, Cunningham M, Brass LF: Changes in the platelet membrane glycoprotein IIb-IIIa complex during platelet activation. J Biol Chem 1985;260:11107-11114.
14. Coller BS, Cheresh DA, Asch E, Seligsohn U: Platelet vitronectin receptor expression differentiates Iraqi-Jewish from Arab patients with Glanzmann thrombasthenia in Israel. Blood 1991;77: 75-83.
15. Stephenson RA, Dinney CPN, Gohji K, Ordonez NG, Killion JJ, Fidler IJ: Metastic model for human prostate cancer using orthotopic implantation in nude mice. J Natl Cancer Inst 1992;84: 951-957.
16. Waters DJ, Janovitz EB, Chan TCK: Spontaneous metastasis of PC-3 cells in athymic mice after implantation in orthotopic or ectopic microenvironments. Prostate 1995;26:227-234.
17. Tang DG, Onoda JM, Steinert BW, Grossi IM, Nelson KV, Umbarger L, Taylor JD, Honn KV: Phenotypic properties of cultured tumor cells: Integrin αIIbβ3 expression, tumor cell induced platelet aggregation and tumor cell adhesion to endothelium as important parameters of experimental metastasis. Int J Cancer 1993;54:339-347.
18. Frachet P, Uzan G, Thavenon D, Denarier E, Prandini MH, Marguerie G: GPIIb and GPIIIa amino acid sequences deduced from human megakaryocyte cDNAs. Mol Biol Rep 1990;14:27-33.
19. Hussain M: Future directions in prostate cancer treatment: An oncologist's perspective. Prostate [Suppl] 1996;6:26-30.
20. Chang YS, Chen YQ, Timar J, Nelson KV, Grossi IM, Fitzgerald LA, Diglio CA, Honn KV: Increased expresion of αIIbβ3 integrin in high lung colonizing subpopulations of murine melanoma cells. Int J Cancer 1992;51:445-451.
21. Fabozzi SJ, Schellhammer PF, El-Mahdi AM: Pulmonary metastases from prostate cancer. Cancer 1995;75:2706-2709.