Ectopic expression of platelet integrin αIIbβ3 in tumor cells from various species and histological origin

International Journal of Cancer

Volumn 72, Issue 4, 1997, Pages 642-648

  Chen, Yong Q ^a   Trikha, Mohit ^b   Gao, Xiang ^b   Bazaz, Rajesh ^b   Porter, Arthur T ^b   Timar, Jozsef ^c   Honn, Kenneth V ^a,b,d  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

^c SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

^d DETROIT MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN;

ANIMAL CELL; ARTICLE; CANCER GROWTH; CELL ADHESION; HUMAN; HUMAN CELL; MEGAKARYOCYTE; MELANOMA; NONHUMAN; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROTEIN EXPRESSION;

ADENOCARCINOMA; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOOD PLATELETS; CELL ADHESION; HUMANS; INTEGRINS; MALE; MELANOMA, EXPERIMENTAL; MICE; MOLECULAR SEQUENCE DATA; NEOPLASMS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; POLYMERASE CHAIN REACTION; PROSTATIC NEOPLASMS; RATS; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; SPECIES SPECIFICITY; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0030738546     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970807)72:4<642::AID-IJC16>3.0.CO;2-D     Document Type: Article

References (22)

1. BLOCK, K.L. and PONCZ, M., Platelet glycoprotein IIb gene expression as a model of megakaryocyte-specitic expression. Stem Cells, 13, 135-145 (1995).
2. BOUKERCHE, H., BERTHIER-VERGNES, O., TABONE, E., DORÉ, J.F., LEUNG, L. and MCGREGOR, J.L., Platelet-melanoma cell interaction is mediated by the glycoprotein IIb-IIIa complex. Blood, 74, 658-663 (1989).
3. CALVETE, J.J., Clues for understanding the structure and function of a prototypic human integrin: the platelet glycoprotein IIb/IIIa complex. Thrombosis Haemostasis, 72, 1-15 (1994).
4. CHANG, Y.S., CHEN, Y.Q., TIMAR, J., NELSON, K.K., GROSSI, I.M., FITZGERALD, L.A., DIGLIO, C.A. and HONN, K.V., Increased expression of αIIbβ3 integrin in subpopulations of murine melanoma cells with high lung-colonizing ability. Int. J. Cancer, 51, 445-451 (1992).
5. CHEN, Y.Q., GAO, X., TIMAR, J., TANG, D.G., GROSSI, I.M., CHELLADURAI, M., KUNICKI, T.J., FLIEGEL, S.E.G., TAYLOR, J.D. and HONN, K.V., Identification of the αIIIbβ3 intesrin in murine melanoma tumor cells. J. biol. Chem., 267, 17314-17320 (1992).
6. CHIANG, H.S., PENG, H.C. and HUANG, T.F., Characterization of integrin expression and regulation on SW-480 human colon adenocarcinoma cells and the effect of rhodostomin on basal and upregulated tumor cell adhesion. Biochim. biophys. Acta, 1224, 506-516 (1994).
7. HEIDENREICH, R., EISMAN, R., SURREY, S., DELGROSSO, K., BENNETT, J.S., SCHWARTZ, E. and PONCZ, M., Organization of the gene for platelet glycoprotein IIb. Biochemistry, 29, 1232-1244 (1990).
8. HYNES, R.O., Integrins: versatility, modulation, and signaling in cell adhesion. Cell, 69, 11-25 (1992).
9. KNUDSEN, K.A., SMITH, L., SMITH, S., KACZEWS, J. and TUSZYNSKI, G.P., Role of IIb-IIIa-like elycoproteins in cell-substratum adhesion of human melanoma cells. J. Cell Physiol., 136, 471-478 (1988).
10. MCGREGOR, B.C., MCGREGOR, J.L., WEISS, L.M., WOOD, G.S., HU, C., BOUKERCHE, H. and WARNKE, R.A., Presence of cytoadhesins (IIb-IIIa-like glycoproteins) on human metastatic melanomas but not on benign melanocytes. Amer. J. clin. Pathol., 92, 495-499 (1989).
11. OLEKSOWICZ, L., MROWIEC, Z., SCHWARTZ, E., KHORSHIDI, M., DUTCHER, J.P. and PUZKIN, E., Characterization of tumor induced platelet aggregation: the role of immunorelated GPIb and GPIIb/IIIa expression by MCF-7 breast cancer cells. Thrombosis Res., 79, 261-274 (1995).
12. PONCZ, M., EISMAN, R., HEIDENREICH, R.A., SILVER, S.M., VILLAIRE, G., SURREY, S., SCHWARTZ, E. and BENNETT, J.S., Structure of the platelet membrane glycoprotein IIb: homology to the alpha subunit of the vitronectin and ribronectin membrane receptors. J. biol. Chem., 262, 8476-8482 (1987).
13. PONCZ, M. and NEWMAN, P., Analysis of rodent platelet glycoprotein IIb: evidence for evolutionarily conserved domains and alternative proteolytic processing. Blood, 75, 1282-1289 (1990).
14. ROSA, J.P., BRAY, P.F., GAYET, O., JOHNSTON, G.I., COOK, R.G., JACKSON, K.W., SCHUMAN, M.A. and MCEVER, R.P., Cloning of glycoprotein IIIa cDNA from human erythroleukemia cells and localization of the gene to chromosome 17. Blood. 72, 593-600 (1988).
15. SHATTIL, S.J., GINSBERG, M.H. and BRUGGE, J.S., Adhesive signaling in platelets. Current Opin. Cell Biol., 6, 695-704 (1994).
16. SUZUKI, S., ARGRAVES, S.W., ARAI, H., LANGUINO, L.R., PIERSBACHER, M.D. and RUOSLAHTI, E., Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs. J. biol. Chem., 262, 14080-14085 (1987).
17. TANG, D.G. and HONN, K.V., Adhesion molecules and tumor metastasis: an update. Invasion Metastasis, 95, 109-122 (1994).
18. TIMAR, J., BAZAZ, R., KIMLER, V.A., HADDAD, M.M., TANG, D.G., ROBERTSON, D., TAYLOR, J.D. and HONN, K.V., Immunomorphological characterization and effects of 12(S)-HETE on a dynamic intracellular pool of the αIIbβ3-integrin in melanoma cells. J. Cell Sci., 108, 2175-2186 (1995).
19. TIMAR, J., TRIKHA, M., SZEKERES, K., BAZAZ, R., TOVARI, J., SILLETTI, S., RAZ, A. and HONN, K.V., Autocrine motility factor signals integrin-mediated metastatic melanoma cell adhesion and invasion. Cancer Res., 56, 1902-1908 (1996).
20. TRIKHA, M., TIMAR, J., LUNDY, S.K., SZEKERES, K., TANG, K., GRIGNON, D., PORTER, A.T. and HONN, K.V., Human prostate carcinoma cells express functional αIIbβ3 integrin. Cancer Res., 56, 5071-5078 (1996).
21. TLISZYNSKI, G.P., KARCZEWSKI, J., SMITH, L., MURPHY, A., ROTHMAN, V.L. and KNUDSEN, K.A., The GP IIb-IIIa-like complex may function as a human melanoma cell adhesion receptor for thrombospondin. Exp. Cell Res., 182, 473-481 (1989).
22. VARNER, J.A. and CHERESH, D.A., Integrins and cancer. Current Opin. Cell Biol., 8, 724-730 (1996).