Effects of liposome-encapsulated drugs on macrophages: Comparative activity of the diamidine 4',6-diamidino-2-phenylindole and the phenanthridinium salts ethidium bromide and propidium iodide

Biochimica et Biophysica Acta - Biomembranes

Volumn 1373, Issue 1, 1998, Pages 93-100

  Bakker, Jeroen ^a   Sanders, Annemarie ^a   Van Rooijen, Nico ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

4',6 Diamidino 2 phenylindole; Ethidium; Kupffer cell; Liposome; Propamidine; Propidium

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; DIAMIDINE DERIVATIVE; ETHIDIUM BROMIDE; LIPOSOME; PROPIDIUM IODIDE;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG EFFECT; KUPFFER CELL; MACROPHAGE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; DRUG CARRIERS; ETHIDIUM; IMMUNOHISTOCHEMISTRY; INDOLES; LIPOSOMES; MACROPHAGES; PROPIDIUM; RATS;

EID: 0032516741     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2736(98)00089-3     Document Type: Article

References (22)

1. N. van Rooijen, The liposome-mediated macrophage 'suicide' technique, J. Immunol. Methods 124 (1989) 1-6.
2. N. van Rooijen, A. Sanders, Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications, J. Immunol. Methods 174 (1994) 83-93.
3. T. Tschaikowsky, J.D. Brain, Effects of liposome-encapsulated dichloromethylene diphosphonate on macrophage functioning and endotoxin-induced mortality, Biochim. Biophys. Acta 1222 (1994) 323-330.
4. I. Huitinga, N. van Rooijen, C.J.A. de Groot, B.M.J. Uitdehaag, C.D. Dijkstra, Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages, J. Exp. Med. 172 (1990) 1025-1033.
5. N. van Rooijen, N. Kors, Effects of intracellular diphosphonates on cells of the mononuclear phagocyte system: in vivo effects of liposome-encapsulated diphosphonates on different macrophage subpopulations in the spleen, Calcif. Tissue Int. 45 (1989) 153-156.
6. N. van Rooijen, A. Sanders, Kupffer cell depletion by liposome-delivered drugs : comparative activity of intracellular clodronate, propamidine, and ethylenediaminetetraacetic acid, Hepatology 23 (1996) 1239-1243.
7. N. van Rooijen, A. Sanders, T.K. Van den Berg, Apoptosis of macrophages induced by liposome-mediated intracellular delivery of clodronate and propamidine, J. Immunol. Methods 193 (1996) 93-99.
8. M. Naito, H. Nagai, S. Kawano, H. Umezu, H. Zhu, H. Moriyama, T. Yamamoto, H. Takatsuka, Y. Takei, Liposome-encapsulated dichloromethylene diphosphonate induces macrophage apoptosis in vivo and in vitro, J. Leukocyte Biol. 60 (1996) 337-344.
9. M.R. Conte, T.C. Jenkins, A.N. Lane, Interactions of minor-groove-binding diamidine ligands with an asymmetric DNA duplex. NMR and molecular modelling studies, Eur. J. Biochem. 229 (1995) 433-444.
10. R. Gambari, C. Nastruzzi, DNA-binding activity and biological effects of aromatic polyamidines, Biochem. Pharmacol. 47 (1994) 599-610.
11. 2, Biochim. Biophys. Acta 1350 (1997) 189-204.
12. C.M. Nunn, T.C. Jenkins, S. Neidle, Crystal structure of d(CGCGAATTCGCG) complexed with propamidine, a short-chain homologue of the drug pentamidine, Biochemistry 32 (1993) 13838-13843.
13. W.D. Wilson, F.A. Tanious, H.J. Barton, R.L. Jones, K. Fox, R.L. Wydra, L. Strekowski, DNA sequence dependent binding modes of 4′,6-diamidino-2-phenylindole (DAPI), Biochemistry 29 (1990) 8452-8461.
14. 31P-NMR analysis of the interaction of propidium and ethidium with DNA, Biopolymers 24 (1985) 1963-1979.
15. N. van Rooijen, N. Kors, M. Van den Ende, C.D. Dijkstra, Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome encapsulated dichloromethylene diphosphonate, Cell Tissue Res. 260 (1990) 215-222.
16. C.D. Dijkstra, E.A. Döpp, P. Joling, G. Kraal, The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies, Immunology 54 (1985) 589-599.
17. W.C. Raschke, S. Baird, P. Ralph, I. Nakoinz, Functional macrophage cell lines transformed by Abelson leukemia virus, Cell 15 (1978) 261-267.
18. I. Nicoletti, G. Migliorati, M.C. Pagliacci, F. Grignani, C. Riccardi, A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flowcytometry, J. Immunol. Methods 139 (1991) 271-279.
19. J.C. Frith, J. Mönkkönen, G.M. Blackburn, R.G.G. Russell, M.J. Rogers, Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5′-(β,γ-dichloromethylene) triphosphate, by mammalian cells in vitro, J. Bone Miner. Res. 12 (1997) 1358-1367.
20. 2 and its interaction with minor groove binding 4′,6-diamidino-2-phenylindole, J. Biol. Chem. 268 (1993) 3944-3951.
21. M. Silvander, K. Edwards, A method to detect leakage of DNA intercalators through liposome membranes, Anal. Biochem. 242 (1996) 40-44.
22. T.G. Cotter, M. Al-Rubeai, Cell death (apoptosis) in cell culture systems, Trends Biotechnol. 13 (1995) 150-155.