Transdermal alniditan delivery by skin electroporation

Journal of Controlled Release

Volumn 54, Issue 3, 1998, Pages 265-272

  Jadoul, A ^a   Lecouturier, N ^a   Mesens, J ^b   Caers, W ^b   Preat V ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

Alniditan; Comparison; Electroporation; Iontophoresis; Mechanism

Indexed keywords

ALNIDITAN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DIFFUSION; ELECTRIC POTENTIAL; ELECTROPORATION; IONTOPHORESIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN PENETRATION; SKIN PERMEABILITY;

ADMINISTRATION, CUTANEOUS; ANIMALS; BENZOPYRANS; DIFFUSION; ELECTROPORATION; HYDROGEN-ION CONCENTRATION; IONTOPHORESIS; LINEAR MODELS; MALE; PROPYLAMINES; PYRIMIDINES; RATS; TRANSCUTANEOUS ELECTRIC NERVE STIMULATION; VASOCONSTRICTOR AGENTS;

EID: 0032516699     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(97)00195-8     Document Type: Article

References (20)

1. E.W. Smith, H.I. Maibach, Percutaneous penetration enhancers, CRC Press, Boca Raton, 1995.
2. Banga A.K., Chien Y.W. Iontophoretic delivery of drug: fundamentals, developments and biomedical applications. J. Control. Rel. 7:1988;1-24.
3. B.H. Sage, Iontophoresis, in: Encyclopaedia of Pharmaceutical Technology, J. Swarbrick, J.C. Boylan (Eds), vol. 8, 1993, pp. 247-217.
4. Jadoul A., Mesens J., Caers W., de Beukelaar F., Crabbé R., Préat V. Transdermal permeation of alniditan by iontophoresis: in vitro optimization and human pharmacokinetic data. Pharm. Res. 13:1996;1347-1352.
5. Prausnitz M.R., Bose V.G., Langer R., Weaver J.C. Electroporation of mammalian skin: a mechanism to enhance transdermal drug delivery. Proc. Natl. Acad. Sci. 90:1993;10504-10508.
6. Vanbever R., Lecouturier N., Préat V. Transdermal delivery of metoprolol by electroporation. Pharm. Res. 11:1994;1657-1662.
7. Chizmadzhev A., Zarnytsin V.G., Weaver J.C., Potts R.O. Mechanism of electroinduced ionic species transport through a multilamellar lipid system. Biophys. J. 68:1995;749-765.
8. Edwards D.A., Prausnitz M.R., Langer R., Weaver J.C. Analysis of enhanced transdermal transport by skin electroporation. J. Control. Rel. 34:1995;211-221.
9. R. Vanbever, Skin electroporation for transdermal drug delivery, PhD thesis, Université catholique de Louvain, Brussels, Belgium, 1997.
10. Pliquett U., Weaver J.C. Electroporation of human skin: simultaneous measurements of changes in the transport of two fluorescent molecules and in the passive electrical properties. Bioelectrochem. Bioenerget. 39:1996;1-12.
11. Vanbever R., Le Boulenge E., Préat V. Transdermal delivery of fentanyl by electroporation. I. Influence of electrical factors. Pharm. Res. 13:1996;559-565.
12. Bommannan D., Tamada J., Leung L., Potts R.O. Effect of electroporation on transdermal iontophoretic delivery of luteinizing releasing hormone (LHRH) in vitro. Pharm. Res. 11:1994;1809-1814.
13. Zewert T.E., Pliquett U.F., Langer R., Weaver J.C. Transdermal transport of DNA antisense oligonucleotides by electroporation. Biochem. Biophys. Res. Commun. 212:1995;286-292.
14. V. Regnier, T. Le Doan, V. Préat, Parameters controlling topical delivery of oligonucleotides by electroporation, J. Drug Targeting, in press.
15. Prausnitz M.R., Edelman E.R., Gimm J.A., Langer R., Weaver J.C. Transdermal delivery of heparin by skin electroporation. Biotechnology. 13:1995;1205-1209.
16. Pliquett U., Langer R., Weaver J.C. Changes in the passive electrical properties of human stratum corneum due to electroporation. Biochim. Biophys. Acta. 1239:1995;111-121.
17. R. Vanbever, D. Skrypczack, A. Jadoul, V. Préat, Comparison of skin electroperturbations induced by iontophoresis and electroporation, in: K.R. Brain, K.A. Walters (Eds.), Prediction of Percutaneous Penetration, vol 4b, STS Publishing, Cardiff, 1996, pp. 243-246.
18. Vanbever R., De Morre N., Préat V. Transdermal delivery of fentanyl by electroporation II. Mechanisms involved in drug transport, Pharm. Res. 13:1996;1360-1366.
19. Prausnitz M.R. Do high voltage pulses cause changes in skin structure? J. Control. Rel. 40:1996;321-326.
20. Vanbever R., Préat V. Factors affecting transdermal delivery of metoprolol by electroporation. Bioelectrochem. Bioenerg. 38:1995;223-228.