메뉴 건너뛰기




Volumn 249, Issue 1, 1998, Pages 17-20

Linomide-mediated protection of oligodendrocytes is associated with inhibition of nitric oxide production and IL-1β expression in Lewis rat glial cells

Author keywords

Experimental allergic encephalomyelitis; Glia; Linomide; Multiple sclerosis; Nitric oxide

Indexed keywords

INTERLEUKIN 1BETA; NITRIC OXIDE; ROQUINIMEX;

EID: 0032511119     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00371-1     Document Type: Article
Times cited : (12)

References (21)
  • 1
    • 0030952824 scopus 로고    scopus 로고
    • Linomide induced suppression of experimental autoimmune neuritis is associated witi downregulated macrophage functions
    • Bai X.F., Shi F.D., Zhu J., Xiao B.G., Hedlund G., Link H. Linomide induced suppression of experimental autoimmune neuritis is associated witi downregulated macrophage functions. J. Neuroimmunol. 76:1997;177-184.
    • (1997) J. Neuroimmunol. , vol.76 , pp. 177-184
    • Bai, X.F.1    Shi, F.D.2    Zhu, J.3    Xiao, B.G.4    Hedlund, G.5    Link, H.6
  • 2
    • 0026057489 scopus 로고
    • Simultaneous preparation of four type enriched glial cultures from rat cerebral cortex
    • Da Cunha A., Vitkovie L. Simultaneous preparation of four type enriched glial cultures from rat cerebral cortex. J. Tiss. Cult. Meth. 13:1991;31-38.
    • (1991) J. Tiss. Cult. Meth. , vol.13 , pp. 31-38
    • Da Cunha, A.1    Vitkovie, L.2
  • 4
    • 0031066657 scopus 로고    scopus 로고
    • Linomide administration to mice attenuates the induction of nitric oxide synthase elicited by lipopolysacchride-activated macrophage and prevents nephritis in MRL/MD-Ipr/Ipr mice
    • Hortelano S., Diaz-Guerra M.J.M., Gonzalez-Garcia A., Leonardo E., Gamallo C., Bosca L., Martinez-A C. Linomide administration to mice attenuates the induction of nitric oxide synthase elicited by lipopolysacchride-activated macrophage and prevents nephritis in MRL/MD-Ipr/Ipr mice. J. Immunol. 158:1997;1402-1408.
    • (1997) J. Immunol. , vol.158 , pp. 1402-1408
    • Hortelano, S.1    Diaz-Guerra, M.J.M.2    Gonzalez-Garcia, A.3    Leonardo, E.4    Gamallo, C.5    Bosca, L.6    Martinez-A, C.7
  • 5
    • 0021885421 scopus 로고
    • Augmentation of mouse natural killer cell activity by LS 2616, a new immunomodulator
    • Kalland T., Alm G., Stalhandske T. Augmentation of mouse natural killer cell activity by LS 2616, a new immunomodulator. J. Immunol. 134:1985;3956-3961.
    • (1985) J. Immunol. , vol.134 , pp. 3956-3961
    • Kalland, T.1    Alm, G.2    Stalhandske, T.3
  • 9
    • 0029832923 scopus 로고    scopus 로고
    • Treatment of secondary progressive multiple sclerosis with the immunomodulator Linomide: A double-blind, placebo-controlled pilot study witi monthly magnetic resonance imaging evaluation
    • Karussis D.M., Meiner Z., Lehmann D., Gomori J., Schwarz A., Linde A., Abramsk O. Treatment of secondary progressive multiple sclerosis with the immunomodulator Linomide: a double-blind, placebo-controlled pilot study witi monthly magnetic resonance imaging evaluation. Neurology. 47:1996;341-346.
    • (1996) Neurology , vol.47 , pp. 341-346
    • Karussis, D.M.1    Meiner, Z.2    Lehmann, D.3    Gomori, J.4    Schwarz, A.5    Linde, A.6    Abramsk, O.7
  • 10
    • 0025820404 scopus 로고
    • Oligodendroglial cell death induced by oxygen radical; and its Drotection bv catalase
    • Kim Y.S., Kim S.U. Oligodendroglial cell death induced by oxygen radical; and its Drotection bv catalase. J. Neurosci. Res. 29:1991;100-106.
    • (1991) J. Neurosci. Res. , vol.29 , pp. 100-106
    • Kim, Y.S.1    Kim, S.U.2
  • 11
    • 0024396936 scopus 로고
    • Linomide, a new immunomodulatory drug, shows different effects on homologous versus heterologous collagen-induced arthritis in rats
    • Kleinau S., Larsson P., Bjork J., Holmdahl R., Klareskog L. Linomide, a new immunomodulatory drug, shows different effects on homologous versus heterologous collagen-induced arthritis in rats. Clin. Exp. Immunol. 78:1989;138-142.
    • (1989) Clin. Exp. Immunol. , vol.78 , pp. 138-142
    • Kleinau, S.1    Larsson, P.2    Bjork, J.3    Holmdahl, R.4    Klareskog, L.5
  • 12
    • 0030890184 scopus 로고    scopus 로고
    • Immunomodulation of autoimmunity by Linomide inhibition of antigen presentation through down regulation of macrophage activity in the model of experimental autoimmune encephalomyelitis
    • Lehmann D., Karussis D.M., Fluresco D., Mizrachi-Koll R., Ovadia H., Shezen E., Kalland T., Abramsky O. Immunomodulation of autoimmunity by Linomide inhibition of antigen presentation through down regulation of macrophage activity in the model of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 74:1997;102-110.
    • (1997) J. Neuroimmunol. , vol.74 , pp. 102-110
    • Lehmann, D.1    Karussis, D.M.2    Fluresco, D.3    Mizrachi-Koll, R.4    Ovadia, H.5    Shezen, E.6    Kalland, T.7    Abramsky, O.8
  • 13
    • 0027220214 scopus 로고
    • Nitric oxide localized to spinal cords of mice with experimental allergic encephalomyelitis: An electron paramagnetic resonance study
    • Lin R.F., Lin T.S., Tilton R.G., Cross A.H. Nitric oxide localized to spinal cords of mice with experimental allergic encephalomyelitis: an electron paramagnetic resonance study. J. Exp. Med. 178:1993;643-648.
    • (1993) J. Exp. Med. , vol.178 , pp. 643-648
    • Lin, R.F.1    Lin, T.S.2    Tilton, R.G.3    Cross, A.H.4
  • 14
    • 0028641607 scopus 로고
    • Interferon-y, interleukin-4 and transforming growth factor-(mRNA expression in multiple sclerosis and myasthenia gravis
    • Link, J. Interferon-y, interleukin-4 and transforming growth factor-(mRNA expression in multiple sclerosis and myasthenia gravis. Acta. Neurol. Scand., 90 (1994) Suppl 158 1-58.
    • (1994) Acta. Neurol. Scand. , vol.90 , Issue.SUPPL. 158 , pp. 1-58
    • Link, J.1
  • 15
    • 0027161216 scopus 로고
    • Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide
    • Merril J.E., Ignarro L.J., Sherman M.P., Melinek J., Lane T.E. Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J. Immunol. 151:1993;2132-2141.
    • (1993) J. Immunol. , vol.151 , pp. 2132-2141
    • Merril, J.E.1    Ignarro, L.J.2    Sherman, M.P.3    Melinek, J.4    Lane, T.E.5
  • 16
    • 0020004747 scopus 로고
    • Decreased NK killing in patients with MS: An analysis of the level of the single effector cell in periphera blood and cerebrospinal fluid in relation to the activity of the disease
    • Merrill J., Jondal M., Seeley J., Ullberg M., Siden A. Decreased NK killing in patients with MS: an analysis of the level of the single effector cell in periphera blood and cerebrospinal fluid in relation to the activity of the disease. Clin. Exp. Immunol. 47:1982;419-430.
    • (1982) Clin. Exp. Immunol. , vol.47 , pp. 419-430
    • Merrill, J.1    Jondal, M.2    Seeley, J.3    Ullberg, M.4    Siden, A.5
  • 19
    • 0023252003 scopus 로고
    • MHC antiger expression on bulk isolated macrophage-microglia from newborn mouse brain induction of Ia antigen expression by y-interferon
    • Suzumura A., Mezitis S.G.E., Gonatas N.K., Siberberg D.H. MHC antiger expression on bulk isolated macrophage-microglia from newborn mouse brain induction of Ia antigen expression by y-interferon. J. Neuroimmunol. 15:1987;263-278.
    • (1987) J. Neuroimmunol. , vol.15 , pp. 263-278
    • Suzumura, A.1    Mezitis, S.G.E.2    Gonatas, N.K.3    Siberberg, D.H.4
  • 21
    • 0031044539 scopus 로고    scopus 로고
    • Linomide supresses both Th1 and Th2 cytokines in experimental auto immune myasthenia gravis
    • Zhang G.X., Yu L.Y., Shi F.D., Xiao B.G., Björk J., Hedlund G., Link H. Linomide supresses both Th1 and Th2 cytokines in experimental auto immune myasthenia gravis. J. Neuroimmunol. 73:1997;175-182.
    • (1997) J. Neuroimmunol. , vol.73 , pp. 175-182
    • Zhang, G.X.1    Yu, L.Y.2    Shi, F.D.3    Xiao, B.G.4    Björk, J.5    Hedlund, G.6    Link, H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.