Spectinomycin kinase from Legionella pneumophila: Characterization of substrate specificity and identification of catalytically important residues

Journal of Biological Chemistry

Volumn 273, Issue 24, 1998, Pages 14788-14795

  Thompson, Paul R ^a   Hughes, Donald W ^b   Cianciotto, Nicholas P ^c   Wright, Gerard D ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE DERIVATIVE; AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; APRAMYCIN; BUTIROSIN; KANAMYCIN; NEOMYCIN; PROTEIN KINASE; SPECTINOMYCIN; SPECTINOMYCIN KINASE; STREPTOMYCIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; ENZYME SPECIFICITY; LEGIONELLA PNEUMOPHILA; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; PROTON NUCLEAR MAGNETIC RESONANCE; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

ADENOSINE; ADENOSINE TRIPHOSPHATE; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DRUG RESISTANCE; KINETICS; LEGIONELLA PNEUMOPHILA; LEGIONNAIRES' DISEASE; MAGNETIC RESONANCE SPECTROSCOPY; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; FELIS CATUS; LEGIONELLA PNEUMOPHILA;

EID: 0032510981     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.24.14788     Document Type: Article

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