A convenient synthesis of 5'-amino-5'-deoxythymidine and preparation of peptide-DNA hybrids

Tetrahedron Letters

Volumn 39, Issue 24, 1998, Pages 4215-4218

  Tetzlaff, Charles N ^a   Schwope, Ina ^a   Bleczinski, Colleen F ^a   Steinberg, Joshua A ^a   Richert, Clemens ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

Mitsunobu reactions; Nucleic acid analogues; Nucleosides

Indexed keywords

5' AMINOTHYMIDINE; DNA HYBRID; THYMIDINE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; CHROMATOGRAPHY; DNA LIBRARY; DRUG SYNTHESIS; NONHUMAN; PEPTIDE SYNTHESIS; PROTEIN ASSEMBLY; SOLID PHASE EXTRACTION;

EID: 0032508016     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00788-6     Document Type: Article

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18. 2O, 300MHz, low field region only): δ 7.96, 7.91, 7.65, 7.58, 7.53, 7.39 (6s, 6×1H) and 7.80 (s, 2H) (H8, H2 purines); 7.17, 6.72 (2d, 2×1H, H-6 C); 6.79 (m, 2H), 6.59 (m, 1H), 6.50 (s, 1H) and 6.22 (m 2H) (Trp ring H, H-6 T); 5.92, 5.79, 5.70 (3t, 3×1H), 5.60 (m, 2H) and 5.48 (m, 3H) (H-1′); 5.19, 5.06 (2d, 2×1H, H-5 C).
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