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Volumn 12, Issue 13, 1998, Pages 1625-1630

Treatment response and durability of a double protease inhibitor therapy with saquinavir and ritonavir in an observational cohort of HIV-1-infected individuals

Author keywords

Antiviral therapy; HIV; Protease inhibitor; Ritonavir; Saquinavir

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; LAMIVUDINE; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; STAVUDINE; VIRUS RNA; ZIDOVUDINE;

EID: 0032505088     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199813000-00009     Document Type: Article
Times cited : (49)

References (21)
  • 1
    • 2442723342 scopus 로고    scopus 로고
    • Treatment of human immunodeficiency virus infection with saquinavir, zidovudine and zalcitabine
    • Collier AC, Coombs RW, Schoenfeld DA, et al.: Treatment of human immunodeficiency virus infection with saquinavir, zidovudine and zalcitabine. N Engl J Med 1996, 334:1011-1017.
    • (1996) N Engl J Med , vol.334 , pp. 1011-1017
    • Collier, A.C.1    Coombs, R.W.2    Schoenfeld, D.A.3
  • 2
    • 0030869269 scopus 로고    scopus 로고
    • Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy
    • Gulick R, Mellors J, Havlir D, et al.: Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy. N Engl J Med 1997, 337:734-739.
    • (1997) N Engl J Med , vol.337 , pp. 734-739
    • Gulick, R.1    Mellors, J.2    Havlir, D.3
  • 3
    • 0442268112 scopus 로고    scopus 로고
    • A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less
    • Hammer SM, Squirres KL, Hughes MD, et al.: A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. N Engl J Med 1997, 337:725-733.
    • (1997) N Engl J Med , vol.337 , pp. 725-733
    • Hammer, S.M.1    Squirres, K.L.2    Hughes, M.D.3
  • 4
    • 0029824426 scopus 로고    scopus 로고
    • In vivo resistance to a human immunodeficiency virus type 1 proteinase inhibitor: Mutations, kinetics and frequencies
    • Jacobsen H, Haenggi M, Ott M, et al.: In vivo resistance to a human immunodeficiency virus type 1 proteinase inhibitor: mutations, kinetics and frequencies. J Infect Dis 1996, 173:1379-1387.
    • (1996) J Infect Dis , vol.173 , pp. 1379-1387
    • Jacobsen, H.1    Haenggi, M.2    Ott, M.3
  • 5
    • 0030792728 scopus 로고    scopus 로고
    • Toxicity, efficacy, plasma drug concentrations and protease mutations in patients with advanced HIV infection treated with ritonavir plus saquinavir
    • Lorenzi P, Yerli S, Abderrakim K, et al.: Toxicity, efficacy, plasma drug concentrations and protease mutations in patients with advanced HIV infection treated with ritonavir plus saquinavir. AIDS 1997, 11:F95-F99.
    • (1997) AIDS , vol.11
    • Lorenzi, P.1    Yerli, S.2    Abderrakim, K.3
  • 6
    • 15444377672 scopus 로고    scopus 로고
    • Ordered accumulation of mutations in HIV protease confers resistance to ritonavir
    • Molla A, Korneyeva M, Gao Q, et al.: Ordered accumulation of mutations in HIV protease confers resistance to ritonavir Nature Med 1996, 2:760-766.
    • (1996) Nature Med , vol.2 , pp. 760-766
    • Molla, A.1    Korneyeva, M.2    Gao, Q.3
  • 7
    • 0030012398 scopus 로고    scopus 로고
    • Resistance-related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538)
    • Schmidt JC, Ruiz L, Clotel B, et al.: Resistance-related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538). AIDS 1996, 10:993-999.
    • (1996) AIDS , vol.10 , pp. 993-999
    • Schmidt, J.C.1    Ruiz, L.2    Clotel, B.3
  • 8
    • 0029614884 scopus 로고
    • Drug-resistance patterns of saquinavir and other HIV protease inhibitors
    • Roberts NA: Drug-resistance patterns of saquinavir and other HIV protease inhibitors. AIDS 1995, 9 (Suppl 2):S27-S32.
    • (1995) AIDS , vol.9 , Issue.2 SUPPL.
    • Roberts, N.A.1
  • 9
    • 0029070347 scopus 로고
    • Resistance of HIV type 1 to protease inhibitor Ro 31-8959
    • Eberle J, Bechowsky B, Rose D, et al.: Resistance of HIV type 1 to protease inhibitor Ro 31-8959. AIDS Hum Retrovir 1995, 11:671-676.
    • (1995) AIDS Hum Retrovir , vol.11 , pp. 671-676
    • Eberle, J.1    Bechowsky, B.2    Rose, D.3
  • 10
    • 0029806127 scopus 로고    scopus 로고
    • Rational approaches to resistance: Using saquinavir
    • Boucher C: Rational approaches to resistance: using saquinavir. AIDS 1996, 10 (Suppl 1):S13-S19.
    • (1996) AIDS , vol.10 , Issue.1 SUPPL.
    • Boucher, C.1
  • 11
    • 10344263394 scopus 로고    scopus 로고
    • Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor
    • Condra JH, Holder DJ, Schleif WA, et al.: Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol 1996, 70:8270-8276.
    • (1996) J Virol , vol.70 , pp. 8270-8276
    • Condra, J.H.1    Holder, D.J.2    Schleif, W.A.3
  • 12
    • 0028943992 scopus 로고
    • In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors
    • Condra JH, Schleif WA, Blahy OM, et al.: In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors. Nature 1995, 374:569-571.
    • (1995) Nature , vol.374 , pp. 569-571
    • Condra, J.H.1    Schleif, W.A.2    Blahy, O.M.3
  • 13
    • 0029133978 scopus 로고
    • Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitors
    • Tisdale M, Myers RE, Maschera B, et al.: Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitors. Antimicrob Agent Chemother 1995, 39:1704-1710.
    • (1995) Antimicrob Agent Chemother , vol.39 , pp. 1704-1710
    • Tisdale, M.1    Myers, R.E.2    Maschera, B.3
  • 14
    • 0031054507 scopus 로고    scopus 로고
    • Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients
    • Merry C, Barry MG, Mulcahy F, et al.: Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients. AIDS 1997, 11:F29-F33.
    • (1997) AIDS , vol.11
    • Merry, C.1    Barry, M.G.2    Mulcahy, F.3
  • 15
    • 0027115003 scopus 로고
    • Guidelines for the performance of CD4+ T-cell determinations in persons with human immunodeficiency infection
    • Center for Disease Control (CDC), Atlanta (USA): Guidelines for the performance of CD4+ T-cell determinations in persons with human immunodeficiency infection. MMWR 1992, 1 (No. RR-8):1-17.
    • (1992) MMWR , vol.1 , Issue.RR-8 , pp. 1-17
  • 16
    • 0028806725 scopus 로고
    • A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection
    • Markowitz M, Saag M, Powderly WG, et al.: A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection. N Engl J Med 1995, 333:1534-1539.
    • (1995) N Engl J Med , vol.333 , pp. 1534-1539
    • Markowitz, M.1    Saag, M.2    Powderly, W.G.3
  • 17
    • 0028846165 scopus 로고
    • A short-term study of safety, pharmacokinetics and efficacy of ritonavir, an inhibitor of HIV-1 protease
    • Danner SDA, Carr A, Leonard JM, et al.: A short-term study of safety, pharmacokinetics and efficacy of ritonavir, an inhibitor of HIV-1 protease. N Engl J Med 1995, 333;1528-1533.
    • (1995) N Engl J Med , vol.333 , pp. 1528-1533
    • Danner, S.D.A.1    Carr, A.2    Leonard, J.M.3
  • 18
    • 0029902401 scopus 로고    scopus 로고
    • Improved tolerability of ritonavir derived from pharmacokinetic principles
    • Merry C, Barry M, Gibbons S, Mulcahy F, Back D: Improved tolerability of ritonavir derived from pharmacokinetic principles. Br J Clin Pharmacol 1996, 42:787.
    • (1996) Br J Clin Pharmacol , vol.42 , pp. 787
    • Merry, C.1    Barry, M.2    Gibbons, S.3    Mulcahy, F.4    Back, D.5
  • 19
    • 0032537042 scopus 로고    scopus 로고
    • Indinavir-associated lipodystrophy
    • Viraben R, Aquilina C: Indinavir-associated lipodystrophy. AIDS 1998, 12:137-139.
    • (1998) AIDS , vol.12 , pp. 137-139
    • Viraben, R.1    Aquilina, C.2
  • 20
    • 0032554528 scopus 로고    scopus 로고
    • Abnormal fat accumulation in patients with HIV-1 infection
    • Lipsky JJ: Abnormal fat accumulation in patients with HIV-1 infection. Lancet 1998, 351:847-848.
    • (1998) Lancet , vol.351 , pp. 847-848
    • Lipsky, J.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.