Infrared MALDI mass spectrometry of large nucleic acids

Science

Volumn 281, Issue 5374, 1998, Pages 260-262

  Berkenkamp, Stefan ^a   Kirpekar, Finn ^b   Hillenkamp, Franz ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ARTICLE; DNA DETERMINATION; INFRARED SPECTROMETRY; MASS SPECTROMETRY; NUCLEIC ACID ANALYSIS; PRIORITY JOURNAL; RNA ANALYSIS; STRUCTURE ANALYSIS;

CALIBRATION; DNA; GLYCEROL; MOLECULAR WEIGHT; PLASMIDS; POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0032503987     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.281.5374.260     Document Type: Article

References (20)

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13. -2 Pa, before sample introduction into the spectrometer.
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20. This work was done in partial fulfillment of the requirements for the degree of Ph.D. of S.B. at the University of Münster. Financial support from grant Hi 285/8-2 of the German National Research Council and grant IVA1-800 985 96 of the Department of Education and Research of the State of Northrhine Westfalia is greatly appreciated. We thank J. P. Siebrasse for help with the PCR, T. Becker for assistance with the nanoliter dispensing, and K. Dreisewerd for helpful discussions.