The first total synthesis of (-)-benzomalvin A and benzomalvin B via the intramolecular aza-Wittig reactions

Tetrahedron

Volumn 54, Issue 28, 1998, Pages 7997-8008

  Sugimori, Toshiyuki ^a   Okawa, Tomohiro ^a   Eguchi, Shoji ^a   Kakehi, Akikazu ^b   Yashima, Eiji ^a   Okamoto, Yoshio ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b SHINSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOMALVIN A; BENZOMALVIN B; MALVIN; PHENYLALANINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 0032499996     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(98)00437-2     Document Type: Article

References (27)

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24. 18 Our previous total synthesis of benzomalvin B from sarcosine methyl ester via addition of benzaldehyde to the corresponding quinazolino[3,2-α][1,4]benzodiazepine derivative was accomplished (overall yield 0.9%).
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27. 21 The authors have deposited atomic coordinates for benzomalvin A with the Cambridge Crystallographic Data Centre. The coordinates can be obtained, on request, from the Director, Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge, CB2 1EZ, UK.