A novel and facile carbodiimide-mediated synthesis of 2,3-dihydro-6H-pyrimido[2,1-b]quinazolin-4(1H)-ones via a tandem intramolecular nucleophilic addition/intramolecular hetero conjugate addition annulation strategy

Tetrahedron Letters

Volumn 37, Issue 50, 1996, Pages 9071-9072

  Saito, Takao ^a   Tsuda, Kensaku ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYANAMIDE; QUINAZOLINONE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; CONJUGATION; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0030577451     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02131-4     Document Type: Article

References (22)

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17. 6. To the best of our knowledge, only a few pyrimido[2,1-b]quinazoline derivatives are known and they have been reported to display interesting biological and pharmacological properties such as depressive action on the central nervous system, and neuroleptic and diuretic activity: Korzycka, L.; Szadowska, A.; Pakulska, W. Pharmazie, 1994, 49, 815; Chem. Abstr. 1995, 122, 105798g. Yamamoto, M.; Koshiba, M.; Aono, S. German Patent 2,838,846; Chem. Abstr. 1979, 90, 204132n.
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