Human IL-1 receptor antagonist from Escherichia coli: Large-scale microbial growth and protein purification

Journal of Biotechnology

Volumn 64, Issue 2-3, 1998, Pages 187-196

  Zanette, Dino ^a   Dundon, William ^a   Soffientini, Adolfo ^a   Sottani, Cristina ^a   Marinelli, Flavia ^a   Akeson, Ann ^b   Sarubbi, Edoardo ^a  

^a Gruppo Lepetit SpA   (Italy)

^b SANOFI   (France)

Author keywords

Downstream processing; Expanded bed adsorption; Fermentation; Recombinant protein

Indexed keywords

ADSORPTION; BIOASSAY; BIOREACTORS; DIALYSIS; ENZYME INHIBITION; ESCHERICHIA COLI; FERMENTATION; MICROORGANISMS; PROTEINS; PURIFICATION; SOLUBILITY;

CELLULAR ASSAYS; CYTOKINE; EXPANDED BED ADSORPTION; INTERLEUKIN RECEPTOR ANTAGONIST; PRO-INFLAMMATORY ACTIVITIES; RECOMBINANT PROTEIN;

GROWTH KINETICS;

INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ARTICLE; BIOREACTOR; BIOSYNTHESIS; ESCHERICHIA COLI; FERMENTATION; MASS SPECTROMETRY; MICROBIAL GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION;

ANIMALS; BIOREACTORS; CHO CELLS; CHROMATOGRAPHY, ION EXCHANGE; CRICETINAE; ESCHERICHIA COLI; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; MACACA FASCICULARIS; RECOMBINANT PROTEINS; SIALOGLYCOPROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

ESCHERICHIA COLI; MACACA FASCICULARIS;

EID: 0032497728     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1656(98)00111-4     Document Type: Article

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