Binding interaction of the heregulinβ egf domain with ErbB3 and ErbB4 receptors assessed by alanine scanning mutagenesis

Journal of Biological Chemistry

Volumn 273, Issue 19, 1998, Pages 11667-11674

  Jones, Jennifer T ^a   Ballinger, Marcus D ^a,b   Pisacane, Paul I ^a   Lofgren, Julie A ^a   Fitzpatrick, V Danial ^a,c   Fairbrother, Wayne J ^a   Wells, James A ^a   Sliwkowski, Mark X ^a,b,c  

^a GENENTECH INC   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c PHARMACOPEIA INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NEU DIFFERENTIATION FACTOR; PROTEIN TYROSINE KINASE; TRANSFORMING GROWTH FACTOR; ALANINE; CARRIER PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; GLYCOPROTEIN; HEREGULIN BETA1; LIGAND; ONCOPROTEIN; PROTEIN KINASE (CALCIUM,CALMODULIN);

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; HUMAN; LIGAND BINDING; MUTAGENESIS; PHAGEMID; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; ULTRASTRUCTURE;

ALANINE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CARRIER PROTEINS; ENZYME ACTIVATION; GLYCOPROTEINS; HUMANS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NEUREGULIN-1; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTO-ONCOGENE PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-3; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0032495872     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.19.11667     Document Type: Article

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