Pharmacological reduction of electrophysiological diaschisis after photothrombotic ischemia in rat neocortex

European Journal of Pharmacology

Volumn 320, Issue 2-3, 1997, Pages 103-109

  Buchkremer Ratzmann, Irmgard ^a   Witte, Otto W ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Ischemia, focal; Nitric oxide (NO); NMDA receptor antagonist; Photochemical infarction, treatment

Indexed keywords

CYCLIC GMP; DIZOCILPINE; GLIAL FIBRILLARY ACIDIC PROTEIN; LUBELUZOLE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX LESION; BRAIN INFARCTION; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN SLICE; IMMEDIATE EARLY GENE; INTRAVENOUS DRUG ADMINISTRATION; LIGHT DAMAGE; MALE; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CEREBRAL CORTEX; DERMATITIS, PHOTOTOXIC; DISEASE MODELS, ANIMAL; DIZOCILPINE MALEATE; ELECTROPHYSIOLOGY; EVOKED POTENTIALS; EXCITATORY AMINO ACID ANTAGONISTS; INTRACRANIAL EMBOLISM AND THROMBOSIS; ISCHEMIC ATTACK, TRANSIENT; MALE; NEUROPROTECTIVE AGENTS; PIPERIDINES; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; THIAZOLES;

EID: 0031565266     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00891-6     Document Type: Article

References (56)

1. Andrews, R.J., 1991, Transhemispheric diaschisis, Stroke 22, 943.
2. Barth, T.M., M.L. Grant and T. Schallert, 1994, Effects of MK-801 on recovery from sensorimotor cortex lesions, Stroke 21 (Suppl. 3), 153.
3. Buchan, A.M., A. Slivka and D. Xue, 1992, The effect of the NMDA receptor antagonist MK-801 on cerebral blood flow and infarct volume in experimental focal stroke, Brain Res. 574, 171.
4. Buchkremer-Ratzmann, I., M. August, G. Hagemann and O.W. Witte, 1996, Electrophyiological transcortical diaschisis after cortical thrombosis in the rat brain, Stroke 27, 1105.
5. Choi, D.W. and S.M. Rothmann, 1990, The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death, Annu. Rev. Neurosci. 13, 171.
6. Clineschmidt, B.V., 1982, Effect of the benzodiazepine receptor antagonist Ro 15-1788 on the anticonvulsant and anticonflict actions of MK-801, Eur. J. Pharmacol. 84, 119.
7. Corbett, D., S. Evans, C. Thomas, D. Wang and A.D. Jonas, 1990, MK-801 reduced cerebral ischemic injury by inducing hypothermia, Brain Res. 514, 300.
8. Dawson, D.A., 1994, Nitric oxide and focal cerebral ischemia: multiplicity of actions and diverse outcome, Cerebrovasc. Brain Metab. Rev. 6, 299.
9. De Ryck, M., J. De Keyser, A.S. Lesage, L. Hantson and W. Swijzen, 1995, Lubeluzole reduces mortality and improves functional oucome in the treatment of acute ischemic stroke: early preclinical and clinical findings, in: Ischemic Stroke. Recent Advances in Understanding Therapy, eds. J. Grotta, L.P. Miller and A.M. Buchan (International Business Communications, Southborough, MA) p. 271.
10. De Ryck, M., R. Keersmaekers, H. Duytschaever, C. Claes, G. Clincke, M. Janssen and G. Van Reet, 1996, Lubeluzole protects sensorimotor function and reduces infarct size in a photochemical stroke model in rats, J. Pharmacol. Exp. Ther. (in press).
11. Dietrich, W.D., M.D. Ginsberg, R. Busto and B.D. Watson, 1986, Photochemical induced cortical infarction in the rat. 2. Acute and subacute alterations in local glucose utilisation, J. Cereb. Blood Flow Metab. 6, 195.
12. Dietrich, W.D., Z.-C. Feng, H. Leistra, B.D. Watson and M. Rosenthal, 1994, Photothrombotic infarction triggers multiple episodes of cortical spreading depression in distant brain regions, J. Cereb. Blood Flow Metab. 14, 20.
13. Dirnagl, U., J. Tanabe and W. Pulsinelli, 1990, Pre- and post-treatment with MK-801 but not pretreatment alone reduces neocortical damage after focal cerebral ischemia in the rat, Brain Res. 527, 62.
14. Domann, R., G. Hagemann, M. Kraemer, H.-J. Freund and O.W. Witte, 1993, Electrophysiological changes in the surrounding brain tissue of photochemically induced corical infarcts in the rat, Neurosci. Lett. 155, 69.
15. Foster, A.C. and E.H.F. Wong, 1987, The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain, Br. J. Pharmacol. 91, 403.
16. Foster, A.C., R. Gill and G.N. Woodruff, 1988, Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation, J. Neurosci. 8, 4745.
17. Garthwaite, J., 1991, Glutamate, nitric oxide and cell-cell signaling in the nervous system, Trends Neurosci. 14, 60.
18. Gass, P., M. Spranger, T. Herdegen, R. Bravo, P. Köck, W. Hacke and M. Kiessling, 1992, Induction of FOS and JUN proteins after focal ischemia in the rat: differential effect of the N-methyl-D-aspartate receptor antagonist MK-801, Acta Neuropathol. (Berlin) 84, 545.
19. Gill, R., P. Andine, L. Hillered, L. Persson and H. Hagberg, 1992, The effect of MK-801 on cortical spreading depression in the penumbral zone following focal ischaemia in the rat, J. Cereb. Blood Flow Metab. 12, 371.
20. Ginsberg, M.D. and R. Busto, 1989, Rodent models of cerebral ischemia, Stroke 20, 1627.
21. Grome, J.J., G. Gojowczky, W. Hofmann and D.I. Graham, 1988, Quantitation of photochemically induced focal cerebral ischemia in the rat, J. Cereb. Blood Flow Metab. 8, 89.
22. 2+: toxicity is blocked by the N-methyl-D-aspartate antagonist MK-801, Proc. Natl. Acad. Sci. USA 85, 6556.
23. Hansen, A.J. and T. Zeuthen, 1981, Extracellular ion concentrations during spreading depression and ischemia in the rat brain cortex, Acta Physiol. Scand. 113, 437.
24. Hatfield, R.H., R. Gill and C. Brazell, 1992, The dose-response relationship and therapeutic window for dizocilpine (MK-801) in a rat focal ischemia model, Eur. J. Pharmacol. 216, 1.
25. Heiss, W.D., H.G. Emunds and K. Herholz, 1993, Cerebral glucose metabolism as a predictor of rehabilitation after ischemic stroke, Stroke 24, 1784.
26. Heiss, W.D. and K. Herholz, 1994, Assessment of pathophysiology of stroke by positron emission tomography, Eur. J. Nucl. Med. 21, 455.
27. Huang, Z., P.L. Huang, N. Panahian, T. Dalkara, M.C. Fishman and M.A. Moskowitz, 1994, Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase, Science 265, 1883.
28. Hunter, A.J., A.R. Green and A.J. Cross, 1995, Animals models of acute ischaemic stroke: can they predict clinically successful neuroprotective drugs?, Trends Pharmacol. Sci. 16, 123.
29. Iijima, T., G. Mies and K.-A. Hossmann, 1992, Repeated negative DC deflections in rat cortex following middle cerebral artery occlusion are abolished by MK-801: effect on volume of ischemic injury, J. Cereb. Blood Flow Metab. 12, 727.
30. Iversen, L.L., G.N. Woodruff, J.A. Kemp, A.C. Foster, R. Gill and E.H.F. Wong, 1992, Neuroprotective properties of the glutamate anatagonist dizocilpine maleate (MK-801) in animal models of focal and global ischamia, in: Ischaemia, ed. W. Kriegelsteiner (Wiss. Verlag Ges.) p. 165.
31. Lauritzen, M. and A.J. Hansen, 1992, The effect of glutamate receptor blockade on anoxic depolarization and cortical spreading depression, J. Cereb. Blood Flow Metab. 12, 223.
32. Lesage, A.S., L. Peeters and J.E. Leysen, 1996, Lubeluzole, a novel long-term neuroprotectant, inhibits the glutamate-activated nitric oxide synthase pathway, J. Pharmacol. Exp. Ther. (in press).
33. 2 consumption in rat, Brain Res. 669, 35.
34. McLachlan, R.S. and J.P. Girvin, 1994, Spreading depression of Leao in rodent and human brain, Brain Res. 666, 133.
35. Mies, G., S. Ishimaru, Y. Xie, K. Seo and K.-A. Hossmann, 1991, Ischemic thresholds of cerebral protein synthesis and energy state following middle cerebral artery occlusion in rat, J. Cereb. Blood Flow Metab. 11, 753.
36. Monteau, R., P. Gauthier, P. Rega and G. Hilaire, 1990, Effects of N-methyl-D-aspartate (NMDA) antagonist MK-801 on breathing pattern in rats, Neurosci. Lett. 109, 134.
37. Morin, C.L., S. Dolina, R.T. Robertson and C.E. Ribak, 1994, An inbred epilepsy-prone substrain of BALB/c mice shows absence of the corpus callosum, and abnormal projection to the basal forebrain, and bilateral projections to the thalamus, Cereb. Cortex 4, 119.
38. Murad, F., 1994, The role of nitric oxide in modulating guanylyl cyclase, Neurotransmissions 10, 1.
39. Nedergaard, M., 1994, Neuronal injury in the infarct border: a neuropathological study in the rat, Acta Neuropathol. (Berlin) 73, 267.
40. Neumann-Haefelin, T., G. Hagemann and O.W. Witte, 1995, Cellular correlates of neuronal hyperexcitability in the vicinity of photochemically induced cortical infarcts in rats in vitro, Neurosci. Lett. 193, 101.
41. Nowicki, J.P., D. Duval, H. Poignet and B. Scatton, 1991, Nitric oxide mediates neuronal death after focal cerebral ischemia in the mouse, Eur. J. Pharmacol. 204, 339.
42. Park, C.K., D.G. Nehls, D.I. Graham, G.M. Teasdale and J. McCulloch, 1988, The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat, Ann. Neurol. 24, 543.
43. Paxinos, G. and C. Watson, 1986, The Rat Brain in Stereotaxic Coordinates (Academic Press, London).
44. Sae Monn Oh and A.L. Betz, 1991, Interaction between free radicals and exitatory amino acids in the formation of ischemic brain edema in rats, Stroke 22, 915.
45. Scheller, D., J. Kolb, S. Szathmary, E. Zacharias, M. De Ryck, J. Van Reempts, G. Clincke and F. Tegtmeier, 1995, Extracellular changes of glutamate in the peri-infarct zone. Effect of lubeluzole, J. Cereb. Blood Flow Metab. 15, 379 (Abstract).
46. Schiene, K., C. Bruehl, K. Zilles, M. Qü, R. Domann, M. Kraemer and O.W. Witte, 1996, Neuronal hyperexcitability and reduction of GABA receptor expression in the surround of cerebral thrombosis, J. Cereb. Blood Flow Metab. 16, 906.
47. Schroeter, M., K. Schiene, M. Kraemer, G. Hagemann, H. Weigel, U.T. Eysel, O.W. Witte and G. Stoll, 1995, Astroglial responses in photochemically induced focal ischemia of the rat cortex, Exp. Brain Res. 106, 1.
48. Schurr, A., R.S. Payne and B.M. Rigor, 1995, Protection by MK-801 against hypoxia-, excitotoxin-, and depolarization-induced neuronal damage in vitro, Neurochem. Int. 26, 519.
49. Siesjö, B.K., 1992, Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment, J. Neurosurg. 77, 337.
50. Snyder, S.H. and D.M. Sabatini, 1995, Immunophilines and the nervous system, Nature Med. 1, 32.
51. Szatkowski, M. and D. Attwell, 1994, Triggering and execution of neuronal death in brain ischaemia: two phases of glutamate release by different mechanisms, Trends Neurosci. 17, 359.
52. Vincent, S.R., 1994, Nitric oxide: a radical neurotransmitter in the central nervous system, Prog. Neurobiol. 42, 129.
53. Von Monakow, C., 1914, Die Lokalisation im Großhirn und der Abbau der Funktion durch kortikale Herde (J.F. Bergman, Wiesbaden) p. 26.
54. Watson, B.D., W.D. Dietrich, R. Busto, M.S. Wachtel and M.D. Ginsberg, 1985, Induction of reproducible brain infarctions by photochemically initiated thrombosis, Ann. Neurol. 17, 497.
55. Yao, H., M.D. Ginsberg, B.D. Watson, R. Prado, W.D. Dietrich, S. Kraydieh and R. Busto, 1993, Failure of MK-801 to reduce infarct volume in thrombotic middle cerebral artery occlusion in rats, Stroke 24, 864.
56. Zhang, E.T., A.J. Hansen, T. Wieloch and M. Lauritzen, 1990, Influence of MK-801 on brain extracellular calcium and potassium activities in severe hypoglycemia, J. Cereb. Blood Flow Metab. 10, 136.