Identification and sar for a selective, nonpeptidyl thrombin inhibitor

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 13, 1998, Pages 1697-1702

  Naylor Olsen, Adel M ^a   Ponticello, Gerald S ^a   Lewis, S Dale ^a   Mulichak, Anne M ^a   Chen, Zhonguo ^a   Habecker, Charles N ^a   Phillips, Brian T ^a   Sanders, William M ^a   Tucker, Thomas J ^a   Shafer, Jules A ^a   Vacca, Joseph P ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

L 636619; THROMBIN; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; DRUG IDENTIFICATION; DRUG POTENCY; ENZYME BINDING; LIGAND BINDING; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

ANTITHROMBINS; BINDING SITES; CRYSTALLOGRAPHY; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032493422     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00296-0     Document Type: Article

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