Enzymatic synthesis of sialyl-Lewisa-libraries with two non-natural monosaccharide units

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 7, 1998, Pages 755-758

  Baisch, Gabi ^a   Öhrlein, Reinhold ^a   Streiff, Markus ^a   Kolbinger, Frank ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MONOSACCHARIDE; OLIGOSACCHARIDE;

ARTICLE; CARBOHYDRATE SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS;

AMIDES; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; DATABASES; FUCOSYLTRANSFERASES; GANGLIOSIDES; GLUCOSAMINE; GUANOSINE DIPHOSPHATE SUGARS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MONOSACCHARIDES; OLIGOSACCHARIDES; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0032492695     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00092-4     Document Type: Article

References (20)

1. 1) J. Hodgson, Biotechnol. 1990, 8, 108, 421.
2. 2) R. A. Dwek, Chem. Rev. 1996, 96, 683.
3. 3) R. P. McEver, K. L. Moore, R.-D. Cummings, J. Biol. Chem. 1995, 270, 11025.
4. 4) A. Giannis, Angew. Chem. Int. Ed. Engl. 1994, 33, 178.
5. 5) N. E. Robinson, T. de Vries, R. E. Davis, C. L. M. Stults, S. R. Watson, D. H. van den Eijnden, B. A. Macher, Glycobiology 1994, 4, 317.
6. 6) E. Staudacher, TIGG 1996, 8, 391.
7. 7) J. C. McAuliffe, O. Hindsgaul, Chem. & Ind. 1997, 3, 170.
8. 8) S. C. Crawley, M. M. Palcic in: Modern Methods in Carbohydrate Synthesis 1996, 492.
9. 9) C. Hällgren, O. Hindsgaul, J. Carbohydr. Chem. 1995, 14, 453.
10. 10) G. Baisch, R. Öhrlein, A. Katopodis, Bioorg. Med. Chem. Lett. 1996, 24, 2953.
11. 11) G. Baisch, R. Öhrlein, A. Katopodis, M. Streiff, F. Kolbinger, Bioorg. Med. Chem. Lett. 1997, 7, 2447.
12. 12) G. Baisch, R. Öhrlein, A. Katopodis, B. Ernst, Bioorg. Med. Chem. Lett. 1996, 6, 759.
13. 13) G. Baisch, R. Öhrlein, M. Streiff, Bioorg. Med. Chem. Lett. 1998 in print.
14. 14) G. Baisch, R. Öhrlein, A. Katopodis, Bioorg. Med. Chem. Lett. 1997, 7, 2431.
15. 15) K. Sasaki, K. Kurata, K. Funayama, M. Nagata, E. Watanabe, S. Ohta, N. Hanai, T. Nishi, J. Biol. Chem. 1994, 269, 14730.
16. 16) G. Baisch, R. Öhrlein, Bioorg. Med. Chem. 1997, 5, 383.
17. 13C NMR-analysis.
18. 18) P. V. Nikrad, M. A. Kashem, K. B. Wlasichuk, G. Alton, A. P. Venot, Carbohydr. Res. 1993, 250, 145.
19. 19) G. Baisch, R. Öhrlein, M. Streiff, B. Ernst, Bioorg. Med. Chem. Lett. 1996, 6, 755.
20. 20) H. J. M. Gijsen, L. Qiao, W. Fitz, C.-H. Wong, Chem. Rev. 1996, 6, 755.