-
1
-
-
0020072221
-
-
P. J. Whitehouse et al., Science 215, 1237 (1982); K. L. Davis et al., N. Engl. J. Med. 237, 1253 (1992); S. L. Rogers, R. S. Doody, R. C. Mohs, L. T. Friedhoff, Arch. Int. Med. 158, 1021 (1998).
-
(1982)
Science
, vol.215
, pp. 1237
-
-
Whitehouse, P.J.1
-
2
-
-
0020072221
-
-
P. J. Whitehouse et al., Science 215, 1237 (1982); K. L. Davis et al., N. Engl. J. Med. 237, 1253 (1992); S. L. Rogers, R. S. Doody, R. C. Mohs, L. T. Friedhoff, Arch. Int. Med. 158, 1021 (1998).
-
(1992)
N. Engl. J. Med.
, vol.237
, pp. 1253
-
-
Davis, K.L.1
-
3
-
-
0032507788
-
-
P. J. Whitehouse et al., Science 215, 1237 (1982); K. L. Davis et al., N. Engl. J. Med. 237, 1253 (1992); S. L. Rogers, R. S. Doody, R. C. Mohs, L. T. Friedhoff, Arch. Int. Med. 158, 1021 (1998).
-
(1998)
Arch. Int. Med.
, vol.158
, pp. 1021
-
-
Rogers, S.L.1
Doody, R.S.2
Mohs, R.C.3
Friedhoff, L.T.4
-
4
-
-
0001815909
-
-
D. B. Calne, Ed. Saunders, Philadelphia
-
H. Braak and E. Braak, in Neurodegenerative Diseases, D. B. Calne, Ed. (Saunders, Philadelphia, 1994), pp. 585-613.
-
(1994)
Neurodegenerative Diseases
, pp. 585-613
-
-
Braak, H.1
Braak, E.2
-
5
-
-
0014208039
-
-
G. C. Cotzias, M. H. VanWoert, L. M. Schiffer, N. Engl. J. Med. 276, 374 (1967); K. G. Lloyd, L. Davidson, O. Hornykiewicz, J. Pharmacol. Exp. Ther. 195, 453 (1975); D. B. Calne, N. Engl. J. Med. 329, 1021 (1993); R. J. Uitti, J. E. Ahlskog, CNS Drugs 5, 369 (1996)
-
(1967)
N. Engl. J. Med.
, vol.276
, pp. 374
-
-
Cotzias, G.C.1
Vanwoert, M.H.2
Schiffer, L.M.3
-
6
-
-
0016836377
-
-
G. C. Cotzias, M. H. VanWoert, L. M. Schiffer, N. Engl. J. Med. 276, 374 (1967); K. G. Lloyd, L. Davidson, O. Hornykiewicz, J. Pharmacol. Exp. Ther. 195, 453 (1975); D. B. Calne, N. Engl. J. Med. 329, 1021 (1993); R. J. Uitti, J. E. Ahlskog, CNS Drugs 5, 369 (1996)
-
(1975)
J. Pharmacol. Exp. Ther.
, vol.195
, pp. 453
-
-
Lloyd, K.G.1
Davidson, L.2
Hornykiewicz, O.3
-
7
-
-
0027500750
-
-
G. C. Cotzias, M. H. VanWoert, L. M. Schiffer, N. Engl. J. Med. 276, 374 (1967); K. G. Lloyd, L. Davidson, O. Hornykiewicz, J. Pharmacol. Exp. Ther. 195, 453 (1975); D. B. Calne, N. Engl. J. Med. 329, 1021 (1993); R. J. Uitti, J. E. Ahlskog, CNS Drugs 5, 369 (1996)
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 1021
-
-
Calne, D.B.1
-
8
-
-
0029895570
-
-
G. C. Cotzias, M. H. VanWoert, L. M. Schiffer, N. Engl. J. Med. 276, 374 (1967); K. G. Lloyd, L. Davidson, O. Hornykiewicz, J. Pharmacol. Exp. Ther. 195, 453 (1975); D. B. Calne, N. Engl. J. Med. 329, 1021 (1993); R. J. Uitti, J. E. Ahlskog, CNS Drugs 5, 369 (1996)
-
(1996)
CNS Drugs
, vol.5
, pp. 369
-
-
Uitti, R.J.1
Ahlskog, J.E.2
-
9
-
-
0030700891
-
-
S. E. Andrew, Y. P. Goldberg, M. R. Hayden, Hum. Mol. Genet. 6, 2005 (1997); J. F. Gusella, F. Persichetti, M. E. MacDonald, Mol. Med. 3, 238 (1997).
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 2005
-
-
Andrew, S.E.1
Goldberg, Y.P.2
Hayden, M.R.3
-
10
-
-
0030948716
-
-
S. E. Andrew, Y. P. Goldberg, M. R. Hayden, Hum. Mol. Genet. 6, 2005 (1997); J. F. Gusella, F. Persichetti, M. E. MacDonald, Mol. Med. 3, 238 (1997).
-
(1997)
Mol. Med.
, vol.3
, pp. 238
-
-
Gusella, J.F.1
Persichetti, F.2
MacDonald, M.E.3
-
11
-
-
0025276132
-
-
R. L. Albin, A. Reiner, K. D. Anderson, J. B. Penney, A. B. Young, Ann. Neurol. 27, 357 (1990); J. T. Greenamyre and I. Shoulson, in (2), pp. 685-704.
-
(1990)
Ann. Neurol.
, vol.27
, pp. 357
-
-
Albin, R.L.1
Reiner, A.2
Anderson, K.D.3
Penney, J.B.4
Young, A.B.5
-
12
-
-
0025276132
-
-
R. L. Albin, A. Reiner, K. D. Anderson, J. B. Penney, A. B. Young, Ann. Neurol. 27, 357 (1990); J. T. Greenamyre and I. Shoulson, in (2), pp. 685-704.
-
Ann. Neurol.
, Issue.2
, pp. 685-704
-
-
Greenamyre, J.T.1
Shoulson, I.2
-
13
-
-
0031711714
-
-
I. Shoulson and the Parkinson Study Group, Ann. Neurol. 44 (suppl. 1), S160 (1998).
-
(1998)
Ann. Neurol.
, vol.44
, Issue.1 SUPPL.
-
-
Shoulson, I.1
-
14
-
-
0003599422
-
-
Academic Press, New York
-
C. W. Olanow, P. Jenner, M. Youdim, Eds., Neurodegeneration and Neuroprotection in PD (Academic Press, New York, 1996);
-
(1996)
Neurodegeneration and Neuroprotection in PD
-
-
Olanow, C.W.1
Jenner, P.2
Youdim, M.3
-
16
-
-
0028113719
-
-
L. J. Martin et al., Am. J. Pathol. 145, 1358 (1994); D. L. Price, S. S. Sisodia, S. E. Gandy, Curr. Opin. Neurol. 8, 268 (1995); M. H. Polymeropoulos et al., Science 276, 2045 (1997); M. G. Spillantini et al., Nature 388, 839 (1997); C. A. Ross, Neuron 19, 1147 (1997); M. DiFiglia et al., Science 277, 1990 (1997).
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 1358
-
-
Martin, L.J.1
-
17
-
-
0029091572
-
-
L. J. Martin et al., Am. J. Pathol. 145, 1358 (1994); D. L. Price, S. S. Sisodia, S. E. Gandy, Curr. Opin. Neurol. 8, 268 (1995); M. H. Polymeropoulos et al., Science 276, 2045 (1997); M. G. Spillantini et al., Nature 388, 839 (1997); C. A. Ross, Neuron 19, 1147 (1997); M. DiFiglia et al., Science 277, 1990 (1997).
-
(1995)
Curr. Opin. Neurol.
, vol.8
, pp. 268
-
-
Price, D.L.1
Sisodia, S.S.2
Gandy, S.E.3
-
18
-
-
0030744876
-
-
L. J. Martin et al., Am. J. Pathol. 145, 1358 (1994); D. L. Price, S. S. Sisodia, S. E. Gandy, Curr. Opin. Neurol. 8, 268 (1995); M. H. Polymeropoulos et al., Science 276, 2045 (1997); M. G. Spillantini et al., Nature 388, 839 (1997); C. A. Ross, Neuron 19, 1147 (1997); M. DiFiglia et al., Science 277, 1990 (1997).
-
(1997)
Science
, vol.276
, pp. 2045
-
-
Polymeropoulos, M.H.1
-
19
-
-
0030882856
-
-
L. J. Martin et al., Am. J. Pathol. 145, 1358 (1994); D. L. Price, S. S. Sisodia, S. E. Gandy, Curr. Opin. Neurol. 8, 268 (1995); M. H. Polymeropoulos et al., Science 276, 2045 (1997); M. G. Spillantini et al., Nature 388, 839 (1997); C. A. Ross, Neuron 19, 1147 (1997); M. DiFiglia et al., Science 277, 1990 (1997).
-
(1997)
Nature
, vol.388
, pp. 839
-
-
Spillantini, M.G.1
-
20
-
-
0031446233
-
-
L. J. Martin et al., Am. J. Pathol. 145, 1358 (1994); D. L. Price, S. S. Sisodia, S. E. Gandy, Curr. Opin. Neurol. 8, 268 (1995); M. H. Polymeropoulos et al., Science 276, 2045 (1997); M. G. Spillantini et al., Nature 388, 839 (1997); C. A. Ross, Neuron 19, 1147 (1997); M. DiFiglia et al., Science 277, 1990 (1997).
-
(1997)
Neuron
, vol.19
, pp. 1147
-
-
Ross, C.A.1
-
21
-
-
0030752709
-
-
L. J. Martin et al., Am. J. Pathol. 145, 1358 (1994); D. L. Price, S. S. Sisodia, S. E. Gandy, Curr. Opin. Neurol. 8, 268 (1995); M. H. Polymeropoulos et al., Science 276, 2045 (1997); M. G. Spillantini et al., Nature 388, 839 (1997); C. A. Ross, Neuron 19, 1147 (1997); M. DiFiglia et al., Science 277, 1990 (1997).
-
(1997)
Science
, vol.277
, pp. 1990
-
-
DiFiglia, M.1
-
22
-
-
3643124128
-
-
R. N. Rosenberg, S. B. Pruisner, S. DiMauro, R. L. Barchi, Eds. Butterworth-Heineman, Newton, MA
-
J. H. Menkes, in The Molecular and Genetic Basis of Neurological Disease, R. N. Rosenberg, S. B. Pruisner, S. DiMauro, R. L. Barchi, Eds. (Butterworth-Heineman, Newton, MA, 1997), pp. 1273-1290; R. F. Pfeiffer, in Movement Disorders: Neurologic Principles and Practice, R. L. Watts and W. C. Koller, Eds. (McGraw-Hill, New York, 1997), pp. 623-637.
-
The Molecular and Genetic Basis of Neurological Disease
, vol.1997
, pp. 1273-1290
-
-
Menkes, J.H.1
-
23
-
-
0001796275
-
-
R. L. Watts and W. C. Koller, Eds. McGraw-Hill, New York
-
J. H. Menkes, in The Molecular and Genetic Basis of Neurological Disease, R. N. Rosenberg, S. B. Pruisner, S. DiMauro, R. L. Barchi, Eds. (Butterworth-Heineman, Newton, MA, 1997), pp. 1273-1290; R. F. Pfeiffer, in Movement Disorders: Neurologic Principles and Practice, R. L. Watts and W. C. Koller, Eds. (McGraw-Hill, New York, 1997), pp. 623-637.
-
(1997)
Movement Disorders: Neurologic Principles and Practice
, pp. 623-637
-
-
Pfeiffer, R.F.1
-
24
-
-
0027530638
-
-
Parkinson Study Group, N. Engl. J. Med. 328, 176 (1993); Ann. Neurol. 39, 29 (1996); ibid., p. 37; ibid. 43, 318 (1998).
-
(1993)
N. Engl. J. Med.
, vol.328
, pp. 176
-
-
-
25
-
-
0027530638
-
-
Parkinson Study Group, N. Engl. J. Med. 328, 176 (1993); Ann. Neurol. 39, 29 (1996); ibid., p. 37; ibid. 43, 318 (1998).
-
(1996)
Ann. Neurol.
, vol.39
, pp. 29
-
-
-
26
-
-
0027530638
-
-
Parkinson Study Group, N. Engl. J. Med. 328, 176 (1993); Ann. Neurol. 39, 29 (1996); ibid., p. 37; ibid. 43, 318 (1998).
-
Ann. Neurol.
, pp. 37
-
-
-
27
-
-
0031893241
-
-
Parkinson Study Group, N. Engl. J. Med. 328, 176 (1993); Ann. Neurol. 39, 29 (1996); ibid., p. 37; ibid. 43, 318 (1998).
-
(1998)
Ann. Neurol.
, vol.43
, pp. 318
-
-
-
29
-
-
3643076267
-
-
29 August PA no.: PAR-97-1020
-
NINDS Clinical Trial Planning Grant, NIH Guide, vol. 26 (no. 29), 29 August 1997 (PA no.: PAR-97-1020).
-
(1997)
NIH Guide
, vol.26
, Issue.29
-
-
-
31
-
-
0029094141
-
-
J. P. Seibyl et al, Ann. Neurol. 38, 589 (1995); P. K. Morrish, G. V. Sawle, D. J. Brooks, Brain 119, 585 (1996).
-
(1995)
Ann. Neurol.
, vol.38
, pp. 589
-
-
Seibyl, J.P.1
-
32
-
-
0029981856
-
-
J. P. Seibyl et al, Ann. Neurol. 38, 589 (1995); P. K. Morrish, G. V. Sawle, D. J. Brooks, Brain 119, 585 (1996).
-
(1996)
Brain
, vol.119
, pp. 585
-
-
Morrish, P.K.1
Sawle, G.V.2
Brooks, D.J.3
-
33
-
-
0012373116
-
-
P. R. Bär and M. F. Beal, Eds. Dekker, New York
-
I. Shoulson and K. Kieburtz, in Neuroprotection: Fundamental and Clinical Aspects, P. R. Bär and M. F. Beal, Eds. (Dekker, New York, 1997), pp. 457-464.
-
(1997)
Neuroprotection: Fundamental and Clinical Aspects
, pp. 457-464
-
-
Shoulson, I.1
Kieburtz, K.2
-
34
-
-
18544410106
-
-
S. W. Davies et al., Cell 90, 537 (1997); D. L. Price et al., NeuroScience News 1, 21 (1998); D. L. Price and S. S. Sisodia, Annu. Rev. Neurosci. 21, 479 (1998).
-
(1997)
Cell
, vol.90
, pp. 537
-
-
Davies, S.W.1
-
35
-
-
18544410106
-
-
S. W. Davies et al., Cell 90, 537 (1997); D. L. Price et al., NeuroScience News 1, 21 (1998); D. L. Price and S. S. Sisodia, Annu. Rev. Neurosci. 21, 479 (1998).
-
(1998)
NeuroScience News
, vol.1
, pp. 21
-
-
Price, D.L.1
-
36
-
-
0031921466
-
-
S. W. Davies et al., Cell 90, 537 (1997); D. L. Price et al., NeuroScience News 1, 21 (1998); D. L. Price and S. S. Sisodia, Annu. Rev. Neurosci. 21, 479 (1998).
-
(1998)
Annu. Rev. Neurosci.
, vol.21
, pp. 479
-
-
Price, D.L.1
Sisodia, S.S.2
-
38
-
-
18544392423
-
-
J. M. Warrick et al., Cell 93, 939 (1998).
-
(1998)
Cell
, vol.93
, pp. 939
-
-
Warrick, J.M.1
-
40
-
-
0032580354
-
-
W. M. Pardridge, J. Cereb. Blood Flow Metab. 17, 713 (1997); R. Langer, Nature 392, 5 (1998).
-
(1998)
Nature
, vol.392
, pp. 5
-
-
Langer, R.1
-
42
-
-
3643087742
-
-
note
-
Supported by grants from the Huntington's Disease Society of America (NY), the Hereditary Disease Foundation (CA), the National Parkinson Foundation (FL), the Parkinson's Disease Foundation (NY), and the Lucille P. Markey Charitable Trust. The thoughtful suggestions of K. Kieburtz, P. Leber, and D. Oakes are appreciated.
-
-
-
|