The synthesis and biological activity of a novel series of diazepine MMP inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 19, 1998, Pages 2657-2662

  Levin, Jeremy I ^a   DiJoseph, John F ^a   Killar, Loran M ^a   Sung, Amy ^a   Walter, Thomas ^a   Sharr, Michele A ^a   Roth, Catherine E ^a   Skotnicki, Jerauld S ^a   Albright, J Donald ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CGS 27023A; COLLAGENASE; COLLAGENASE 3; DIAZEPINE DERIVATIVE; GELATINASE B; HYDROXAMIC ACID DERIVATIVE; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION;

ANIMALS; ANTINEOPLASTIC AGENTS; AZEPINES; COLLAGENASES; ENZYME INHIBITORS; HYDROXAMIC ACIDS; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 9; MICE; ORGANIC CHEMICALS; PROTEASE INHIBITORS; PYRAZINES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 0032491249     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00473-9     Document Type: Article

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