Proline at position 14 of alamethicin is essential for hemolytic activity, catecholamine secretion from chromaffin cells and enhanced metabolic activity in endothelial cells

Biochimica et Biophysica Acta - Biomembranes

Volumn 1370, Issue 1, 1998, Pages 175-183

  Dathe, Margitta ^a   Kaduk, Christine ^a   Tachikawa, Eiichi ^b   Melzig, Matthias F ^c   Wenschuh, Holger ^d   Bienert, Michael ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b IWATE MEDICAL UNIVERSITY   (Japan)

^c HUMBOLDT UNIVERSITY   (Germany)

^d MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

Author keywords

Alamethicin; Catecholamine secretion; Conformation; Dye release; Hemolytic activity; Metabolic activity

Indexed keywords

ALAMETHICIN; CALCIUM ION; CATECHOLAMINE; PROLINE;

ANIMAL CELL; AORTA; ARTICLE; CATECHOLAMINE RELEASE; CATTLE; CHROMAFFIN CELL; CONTROLLED STUDY; ERYTHROCYTE; HEMOLYSIS; HUMAN; HUMAN CELL; LIPID BILAYER; MEMBRANE BINDING; METABOLIC RATE; NONHUMAN; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

ALAMETHICIN; AMINO ACID SEQUENCE; ANIMALS; CATECHOLAMINES; CATTLE; CHROMAFFIN CELLS; ENDOTHELIUM, VASCULAR; HEMOLYSIS; HUMANS; MOLECULAR SEQUENCE DATA; PROLINE; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0032489594     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2736(97)00260-5     Document Type: Article

References (38)

1. Meyer C.E., Reusser F. Experentia. 23:1967;85-86.
2. Jen W.-C., Jones G.A., Brewer D., Parkinson V.O., Taylor A. J. Appl. Bacteriol. 63:1987;293-298.
3. Rebuffat S., Contraux L., Massias M., Auvin-Guette C., Bodo B. Int. J. Pept. Prot. Res. 41:1993;74-84.
4. El Hajji M., Rebuffat S., Le Doan T., Klein G., Sartre M., Bodo B. Biochim. Biophys. Acta. 978:1989;97-104.
5. Jung G., Dubischar N., Irmscher G., Mayr W., Oekonomopolus R. Chemiker Zeitung. 101:1977;196-201.
6. Brückner H., Graf H., Bokel M. Experentia. 40:1984;1189-1197.
7. Bessler W.G., Ottenbreit B., Irmscher G., Jung G. Biochim. Biophys. Res. Commun. 87:1979;99-105.
8. Irmscher G., Jung G. Eur. J. Biochem. 80:1977;165-174.
9. Nagaoka Y., Iida A., Kambara T., Tachikawa E., Asami K., Fujita T. Biol. Pharm. Bull. 18:1995;640-642.
10. Tachikawa E., Nogimori K., Takahashi S., Mizuma K., Itoh K., Kashimoto T., Nagaoka Y., Iida A., Fujita T. Biochim. Biophys. Acta. 1282:1996;140-148.
11. Wada S.-I., Iida A., Asami K., Tachikawa E., Fujita T. Biochim. Biophys. Acta. 1325:1997;209-214.
12. Takaishi Y., Terada H., Fujita T. Experentia. 36:1980;550-552.
13. Okuda M., Iida A., Uesato S., Nagaoka Y., Fujita T., Takaoshi Y., Terada H. Biol. Pharm. Bull. 17:1994;482-485.
14. Mueller P., Rudin O.D. Nature. 217:1968;713-719.
15. Menestrina G., Voges K.P., Jung G., Boheim G. J. Membr. Biol. 93:1986;111-132.
16. Molle G., Duclohier H., Spach G. FEBS Lett. 224:1987;208-212.
17. Rebuffat S., Hlimi S., Prigent Y., Goulard C., Bodo B. J. Chem. Soc. Perkin Trans. 1:1996;2021-2027.
18. Duclohier H., Molle G., Spach G. Biochim. Biophys. Acta. 987:1989;133-136.
19. Iida A., Uesato S., Shingu T., Nagaoka Y., Kuroda Y., Fujita T. J. Chem. Soc. Perkin Trans. 1:1993;375-379.
20. Nagaoka Y., Iida A., Kambara T., Asami K., Tachikawa E., Fujita T. Biochim. Biophys. Acta. 1283:1996;31-36.
21. Duclohier H., Molle G., Dugast J.-Y., Spach G. Biophys. J. 63:1992;868-873.
22. Kaduk C., Duclohier H., Dathe M., Wenschuh H., Beyermann M., Molle G., Bienert M. Biophys. J. 72:1997;2151-2159.
23. Wenschuh H., Beyermann M., Haber H., Seydel J.K., Krause E., Bienert M., Carpino L.A., El Faham A., Albericio F. J. Org. Chem. 60:1995;405-410.
24. Kaduk C., Wenschuh H., Beyermann M., Forner K., Carpino L.A., Bienert M. Lett. Pept. Sci. 2:1996;285-288.
25. Dathe M., Wieprecht T., Nikolenko H., Handel L., Maloy W.L., Mac Conald D.L., Beyermann M., Bienert M. FEBS Lett. 403:1997;208-212.
26. Tachikawa E., Takahashi S., Furumachi K., Kashimoto T., Iida A., Nagaoka A., Fujita T., Takaishi Y. Mol. Pharmacol. 40:1991;790-797.
27. Weil-Malherbe H., Bone A.D. Biochem. J. 51:1952;311-318.
28. Parce J.W., Owicki J.C., Kersco K.M., Sigal G.N., Wada H.G., Mair V.C., Bousse L.J., Ross K.L., Sikic B.L., Mc Connell H.N. Science. 246:1989;243-247.
29. Dathe M., Schümann M., Wieprecht T., Winkler A., Beyermann M., Krause E., Matsuzaki K., Murase O., Bienert M. Biochemistry. 35:1986;12612-12622.
30. Chen Y.J., Yang J.T., Martinez H.M. Biochemistry. 11:1972;4120-4131.
31. Schwarz G., Beschiaschvili G. Biochim. Biophys. Acta. 979:1989;82-90.
32. Eisenberg D. Ann. Rev. Biochem. 53:1994;595-623.
33. Wieprecht T., Dathe M., Beyermann M., Krause E., Maloy W.L., Mac Donald D., Bienert M. Biochemistry. 36:1997;6124-6132.
34. Nagaoka Y., Iida A., Kambara T., Tachikawa E., Fujita T. Chem. Pharm. Bull. 43:1995;1119-1124.
35. Fonteriz R.I., Lopez M.G., Garcia-Sancho J., Garcia A.G. FEBS Lett. 283:1991;89-92.
36. T.J. Rink, S.B. Hladky in: J.C. Ellory and J.D. Young (Eds.), Red Cell Membranes- A Methodological Approach, Academic Press, London, 1982, pp. 321-334.
37. Mendes S., Windeck I., Lichtnow K.-H., Teuscher E. Pharmazie. 47:1992;930-933.
38. Lopez M.G., Artalejo A.R., Garcia A.G., Neher E., Garcia-Sancho E.J. J. Physiol. 482:1995;15-27.